An evaluation of a clinical pharmacy-directed intervention on blood pressure control

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Main Author: Caroline E. Kicklighter
Format: Artículo científico
Language:en
Published: Centro de investigaciones y Publicaciones Farmacéuticas 2006
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author Caroline E. Kicklighter
author_facet Caroline E. Kicklighter
contents An evaluation of a clinical pharmacy-directed intervention on blood pressure control Caroline E. Kicklighter Kent M. Nelson Tammy L. Humphries Thomas Delate Medicina Hypertension Blood pressure Professional Role Pharmaceutical Services Objective: To compare short and long term bloodpressure control with clinical pharmacy specialistinvolvement to traditional physician management.Setting: A non-profit health maintenanceorganization in the United States coveringapproximately 385,000 lives.Methods: This analysis utilized a prospectiveparallel design. Adult patients with a baseline Bloodpressure&#8805;140/90 mmHg and receiving at least oneantihypertensive medication were eligible for thestudy. Eligible hypertension management patientsat one medical office were referred to the office´sclinical pharmacy specialist (intervention cohort)while at another comparable medical office theyreceived usual physician-directed care (controlcohort). The primary outcome measure wasachievement of a goal BP (<140/90 mmHg) during asix month follow-up. Medical records were alsoreviewed approximately 1.5 years post enrollment toassess long-term BP control after clinical pharmacymanagedpatients returned to usual care.Multivariate analyses were performed to adjust forbaseline cohort differences.Results: One hundred-thirteen and 111 subjects inthe intervention and control cohorts completed thestudy, respectively. At the end of the follow-upperiod, clinical pharmacy-managed subjects weremore likely to have achieved goal BP (64.6%) andreceived a thiazide diuretic (68.1%) compared tocontrol subjects (40.7% and 33.3%, respectively)(adjusted p=0.002 and p<0.001, respectively). Theproportion of clinical pharmacy-managed subjectswith controlled BP decreased to 22.2% afterreturning to usual care (p<0.001).Conclusion: Clinical pharmacy involvement inhypertension management resulted in increased BPcontrol. Loss of long-term control afterdiscontinuation of clinical pharmacy managementsupports a change in care processes that preventpatients from being lost to follow-up. 2006 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69040302 en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.3 Vol.4
format Artículo científico
id redalyc_69040302
institution Redalyc
language en
publishDate 2006
publisher Centro de investigaciones y Publicaciones Farmacéuticas
spellingShingle An evaluation of a clinical pharmacy-directed intervention on blood pressure control
Caroline E. Kicklighter
Medicina
Hypertension
Blood pressure
Professional Role
Pharmaceutical Services
An evaluation of a clinical pharmacy-directed intervention on blood pressure control Caroline E. Kicklighter Kent M. Nelson Tammy L. Humphries Thomas Delate Medicina Hypertension Blood pressure Professional Role Pharmaceutical Services Objective: To compare short and long term bloodpressure control with clinical pharmacy specialistinvolvement to traditional physician management.Setting: A non-profit health maintenanceorganization in the United States coveringapproximately 385,000 lives.Methods: This analysis utilized a prospectiveparallel design. Adult patients with a baseline Bloodpressure&#8805;140/90 mmHg and receiving at least oneantihypertensive medication were eligible for thestudy. Eligible hypertension management patientsat one medical office were referred to the office´sclinical pharmacy specialist (intervention cohort)while at another comparable medical office theyreceived usual physician-directed care (controlcohort). The primary outcome measure wasachievement of a goal BP (<140/90 mmHg) during asix month follow-up. Medical records were alsoreviewed approximately 1.5 years post enrollment toassess long-term BP control after clinical pharmacymanagedpatients returned to usual care.Multivariate analyses were performed to adjust forbaseline cohort differences.Results: One hundred-thirteen and 111 subjects inthe intervention and control cohorts completed thestudy, respectively. At the end of the follow-upperiod, clinical pharmacy-managed subjects weremore likely to have achieved goal BP (64.6%) andreceived a thiazide diuretic (68.1%) compared tocontrol subjects (40.7% and 33.3%, respectively)(adjusted p=0.002 and p<0.001, respectively). Theproportion of clinical pharmacy-managed subjectswith controlled BP decreased to 22.2% afterreturning to usual care (p<0.001).Conclusion: Clinical pharmacy involvement inhypertension management resulted in increased BPcontrol. Loss of long-term control afterdiscontinuation of clinical pharmacy managementsupports a change in care processes that preventpatients from being lost to follow-up. 2006 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69040302 en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.3 Vol.4
title An evaluation of a clinical pharmacy-directed intervention on blood pressure control
topic Medicina
Hypertension
Blood pressure
Professional Role
Pharmaceutical Services
url https://www.redalyc.org/articulo.oa?id=69040302