Factors affecting medication adherence in Lebanese patients with chronic diseases
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Centro de investigaciones y Publicaciones Farmacéuticas
2015
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| _version_ | 1876464715118411776 |
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| author | Amal AL-HAJJE |
| author_facet | Amal AL-HAJJE |
| contents | Factors affecting medication adherence in Lebanese patients with chronic diseases Amal AL-HAJJE Sanaa AWADA Samar RACHIDI Salam ZEIN Wafa BAWAB Zeinab EL-HAJJ Mayssam BOU ZEID Mohammad YASSINE Pascale SALAMEH Medicina Lebanon Causality Prevalence Medication Adherence Multivariate Analysis Background: Non-adherence to prescribed medications represents an obstacle toward achieving treatment goals. This problem is more pronounced in patients with chronic illness. Objective: To identify the extent of adherence in Lebanese outpatients with chronic diseases, and to suggest possible predictors of non-adherence in this population. The secondary objective was to assess if medication adherence affects patients' quality of life. Methods: A questionnaire was administered face-to-face to a sample of Lebanese adults visiting the external clinics at two Tertiary Care Hospitals in Beirut. The level of adherence was assessed using the 8-item Morisky Medication Adherence Scale which was first validated. The health-related quality of life (HRQoL) of patients was measured using the EQ-5D. Linear regression and logistic regression analyses examined possible predictors of adherence. Results: Out of the 148 patients included in this study, 42.6% were classified as adherent. In the univariate analyses, statistically significant predictors of high adherence included good physician-patient relationship (p=0.029) and counseling (p=0.037), a high level of HRQoL (p<0.001), and a high level of perceived health (p<0.001). Predictors of low adherence included a declining memory (p<0.001), anxiety/depression (p=0.002), little drug knowledge (p<0.001), and postponing physician appointments (p<0.001). The multivariate analyses revealed similar results. In the linear regression, the most powerful predictor of non-adherence was the disbelief that the drug is ameliorating the disease (beta=0.279), however, in logistic regression, patient who were willing to skip or double doses in case of amelioration/deterioration were found to be 7.35 times more likely to be non-adherent than those who were not (aOR=0.136, 95%CI: 0.037-0.503). Conclusion: The findings of this study reassure the view that patients should be regarded as active decision makers. Patient education should be regarded as a cornerstone for treatment success. Additional studies as well are needed to test the practicability and effectiveness of interventions suggested to enhance adherence. 2015 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69041179006 https://www.redalyc.org/journal/690/69041179006/ https://www.redalyc.org/journal/690/69041179006/html/ https://www.redalyc.org/journal/690/69041179006/69041179006.epub https://www.redalyc.org/journal/690/69041179006/movil en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.3 Vol.13 |
| format | Artículo científico |
| id | redalyc_69041179006 |
| institution | Redalyc |
| language | en |
| publishDate | 2015 |
| publisher | Centro de investigaciones y Publicaciones Farmacéuticas |
| spellingShingle | Factors affecting medication adherence in Lebanese patients with chronic diseases Amal AL-HAJJE Medicina Lebanon Causality Prevalence Medication Adherence Multivariate Analysis Factors affecting medication adherence in Lebanese patients with chronic diseases Amal AL-HAJJE Sanaa AWADA Samar RACHIDI Salam ZEIN Wafa BAWAB Zeinab EL-HAJJ Mayssam BOU ZEID Mohammad YASSINE Pascale SALAMEH Medicina Lebanon Causality Prevalence Medication Adherence Multivariate Analysis Background: Non-adherence to prescribed medications represents an obstacle toward achieving treatment goals. This problem is more pronounced in patients with chronic illness. Objective: To identify the extent of adherence in Lebanese outpatients with chronic diseases, and to suggest possible predictors of non-adherence in this population. The secondary objective was to assess if medication adherence affects patients' quality of life. Methods: A questionnaire was administered face-to-face to a sample of Lebanese adults visiting the external clinics at two Tertiary Care Hospitals in Beirut. The level of adherence was assessed using the 8-item Morisky Medication Adherence Scale which was first validated. The health-related quality of life (HRQoL) of patients was measured using the EQ-5D. Linear regression and logistic regression analyses examined possible predictors of adherence. Results: Out of the 148 patients included in this study, 42.6% were classified as adherent. In the univariate analyses, statistically significant predictors of high adherence included good physician-patient relationship (p=0.029) and counseling (p=0.037), a high level of HRQoL (p<0.001), and a high level of perceived health (p<0.001). Predictors of low adherence included a declining memory (p<0.001), anxiety/depression (p=0.002), little drug knowledge (p<0.001), and postponing physician appointments (p<0.001). The multivariate analyses revealed similar results. In the linear regression, the most powerful predictor of non-adherence was the disbelief that the drug is ameliorating the disease (beta=0.279), however, in logistic regression, patient who were willing to skip or double doses in case of amelioration/deterioration were found to be 7.35 times more likely to be non-adherent than those who were not (aOR=0.136, 95%CI: 0.037-0.503). Conclusion: The findings of this study reassure the view that patients should be regarded as active decision makers. Patient education should be regarded as a cornerstone for treatment success. Additional studies as well are needed to test the practicability and effectiveness of interventions suggested to enhance adherence. 2015 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69041179006 https://www.redalyc.org/journal/690/69041179006/ https://www.redalyc.org/journal/690/69041179006/html/ https://www.redalyc.org/journal/690/69041179006/69041179006.epub https://www.redalyc.org/journal/690/69041179006/movil en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.3 Vol.13 |
| title | Factors affecting medication adherence in Lebanese patients with chronic diseases |
| topic | Medicina Lebanon Causality Prevalence Medication Adherence Multivariate Analysis |
| url | https://www.redalyc.org/articulo.oa?id=69041179006 https://www.redalyc.org/journal/690/69041179006/ https://www.redalyc.org/journal/690/69041179006/html/ https://www.redalyc.org/journal/690/69041179006/69041179006.epub https://www.redalyc.org/journal/690/69041179006/movil |