Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Centro de investigaciones y Publicaciones Farmacéuticas
2007
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| _version_ | 1876445913706135552 |
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| author | Yan Chen |
| author_facet | Yan Chen |
| contents | Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis Yan Chen Jeff J. Guo Daniel P. Healy Siyan Zhan Medicina Meta Medicine Analysis Chinese Traditional Severe Acute Respiratory Syndrome Background: Data regarding the treatment efficacyof integrative treatment of Traditional ChineseMedicine (TCM) and Western Medicine (WM) intreating patients with (SARS) are conflicting. Theeffects of integrative TCM/WM treatment have notbeen fully quantified.Objectives: To systematically asses the treatmenteffects of integrated TCM with WM versus WMalone in patients with SARS, incorporating datafrom recently published studies.Methods: A meta-analysis was conducted, usingpublished randomized and nonrandomizedcontrolled clinical studies that compared thetreatment effects of integrative TCM/WM with WMalone from 2002 to 2006.The outcomemeasurements included mortality rate, cure rate,resolution of pulmonary infiltrate, use ofcorticosteroid, and time to defervescence. Theeffect sizes were presented as risk ratio (RR), ratedifference (RD), and weighted mean difference(WMD).The pooled effect sizes were calculated byboth fixed-effects and random-effects models.Results: A total of 1,678 patients with a diagnosis ofSARS were identified, including 866 patients from16 randomized controlled studies and 812 patientsfrom 8 nonrandomized controlled studies. Therewere no differences detected in mortality rate orcure rate between treatments. Compared withpatients receiving WM treatment alone, patientsreceiving integrative treatment were more likely tohave complete or partial resolution of pulmonaryinfiltrate (RD=0.18, 95%CI; 0.07 to 0.30), loweraverage daily dosage (mg) of corticosteroid(WMD=-60.27, 95% CI; -70.58 to -49.96), higherCD4+ counts (cells/uL) (WMD=167.96, 95% CI;109.68 to 226.24), and shorter time to defervescence (days) (WMD= -1.06, 95%CI;-1.60 to-0.53).Conclusions: The experience of integrativeTCM/WM in the treatment of SARS is encouraging.The use of TCM as an adjunctive therapy in thetreatment of SARS should be further investigated. 2007 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69050101 https://www.redalyc.org/journal/690/69050101/ https://www.redalyc.org/journal/690/69050101/html/ https://www.redalyc.org/journal/690/69050101/69050101.epub https://www.redalyc.org/journal/690/69050101/movil en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.1 Vol.5 |
| format | Artículo científico |
| id | redalyc_69050101 |
| institution | Redalyc |
| language | en |
| publishDate | 2007 |
| publisher | Centro de investigaciones y Publicaciones Farmacéuticas |
| spellingShingle | Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis Yan Chen Medicina Meta Medicine Analysis Chinese Traditional Severe Acute Respiratory Syndrome Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis Yan Chen Jeff J. Guo Daniel P. Healy Siyan Zhan Medicina Meta Medicine Analysis Chinese Traditional Severe Acute Respiratory Syndrome Background: Data regarding the treatment efficacyof integrative treatment of Traditional ChineseMedicine (TCM) and Western Medicine (WM) intreating patients with (SARS) are conflicting. Theeffects of integrative TCM/WM treatment have notbeen fully quantified.Objectives: To systematically asses the treatmenteffects of integrated TCM with WM versus WMalone in patients with SARS, incorporating datafrom recently published studies.Methods: A meta-analysis was conducted, usingpublished randomized and nonrandomizedcontrolled clinical studies that compared thetreatment effects of integrative TCM/WM with WMalone from 2002 to 2006.The outcomemeasurements included mortality rate, cure rate,resolution of pulmonary infiltrate, use ofcorticosteroid, and time to defervescence. Theeffect sizes were presented as risk ratio (RR), ratedifference (RD), and weighted mean difference(WMD).The pooled effect sizes were calculated byboth fixed-effects and random-effects models.Results: A total of 1,678 patients with a diagnosis ofSARS were identified, including 866 patients from16 randomized controlled studies and 812 patientsfrom 8 nonrandomized controlled studies. Therewere no differences detected in mortality rate orcure rate between treatments. Compared withpatients receiving WM treatment alone, patientsreceiving integrative treatment were more likely tohave complete or partial resolution of pulmonaryinfiltrate (RD=0.18, 95%CI; 0.07 to 0.30), loweraverage daily dosage (mg) of corticosteroid(WMD=-60.27, 95% CI; -70.58 to -49.96), higherCD4+ counts (cells/uL) (WMD=167.96, 95% CI;109.68 to 226.24), and shorter time to defervescence (days) (WMD= -1.06, 95%CI;-1.60 to-0.53).Conclusions: The experience of integrativeTCM/WM in the treatment of SARS is encouraging.The use of TCM as an adjunctive therapy in thetreatment of SARS should be further investigated. 2007 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69050101 https://www.redalyc.org/journal/690/69050101/ https://www.redalyc.org/journal/690/69050101/html/ https://www.redalyc.org/journal/690/69050101/69050101.epub https://www.redalyc.org/journal/690/69050101/movil en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.1 Vol.5 |
| title | Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: A meta-analysis |
| topic | Medicina Meta Medicine Analysis Chinese Traditional Severe Acute Respiratory Syndrome |
| url | https://www.redalyc.org/articulo.oa?id=69050101 https://www.redalyc.org/journal/690/69050101/ https://www.redalyc.org/journal/690/69050101/html/ https://www.redalyc.org/journal/690/69050101/69050101.epub https://www.redalyc.org/journal/690/69050101/movil |