Outcomes of a percutaneous coronary intervention versus coronary artery bypass grafting in octogenarians

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Autor principal: Rokas Šerpytis
Formato: Artículo científico
Lenguaje:en
Publicado: Vilniaus Universitetas 2018
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author Rokas Šerpytis
author_facet Rokas Šerpytis
contents Outcomes of a percutaneous coronary intervention versus coronary artery bypass grafting in octogenarians Rokas Šerpytis Lina Puodžiukaitė Saulius Petrauskas Nerijus Misonis Mantas Kurminas Aleksandras Laucevičius Pranas Šerpytis Medicina octogenarians coronary artery disease coronary artery bypass grafting Percutaneous coronary intervention Background. The data on long-term outcomes for elderly patients with coronary artery disease who undergo invasive treatment is limited. This study aimed to assess long-term outcomes and risk factors for patients over 80 years of age who underwent revascularisation. Methods. This single-centre retrospective study included ≥80-year-old patients who underwent coronary angiography between 2012 and 2014. Among 590 study patients, 411 patients had significant angiographic changes and had either a percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) performed. Baseline patient characteristics, including demographics, comorbidities, survival to hospital discharge, and long term mortality were analysed. Three-year mortality was assessed. Results. Three hundred sixty-nine (89.8%) patients underwent PCI and in 42 (10.2%) CABG was performed. Significant differences between groups were detected in heart failure (PCI – 51.2% vs. CABG – 78.6%; p = 0.001), previous CABG (11.4% vs. 0%; p = 0.014), cardiogenic shock (12.2% vs. 0%; p = 0.008). Hospital mortality rate in the PCI group – 10.6%, CABG – 7.1%; p = 0.787. A median 3-year survival rate in the PCI group – 66.1%, CABG – 66.7%; p = 1.000. Chronic heart failure (OR 2.442; 95% CI: 1.530–3.898, p < 0.001), atrial fibrillation (OR 0.425; 95% CI: 0.261–0.692, p < 0.001), cardiogenic shock (OR 0.120; 95% CI: 0.054–0.270, p = 0.001), and LMCA stenosis (OR 2.104; 95% CI: 1.281–3.456, p = 0.003) were identified as independent 3-year all-cause mortality predictors in multivariate regression analysis. Conclusions. There was no significant difference in hospital mortality and survival rates between elderly patients who underwent PCI or CAGB. The majority of elderly patients underwent a PCI and these patients appeared to experience cardiogenic shock more frequently. 2018 artículo científico 2029-4174 https://www.redalyc.org/articulo.oa?id=694073965002 en http://www.redalyc.org/revista.oa?id=6940 Acta medica Lituanica application/pdf Vilniaus Universitetas Acta medica Lituanica (Lituania) Num.3 Vol.25
format Artículo científico
id redalyc_694073965002
institution Redalyc
language en
publishDate 2018
publisher Vilniaus Universitetas
spellingShingle Outcomes of a percutaneous coronary intervention versus coronary artery bypass grafting in octogenarians
Rokas Šerpytis
Medicina
octogenarians
coronary artery disease
coronary artery bypass grafting
Percutaneous coronary intervention
Outcomes of a percutaneous coronary intervention versus coronary artery bypass grafting in octogenarians Rokas Šerpytis Lina Puodžiukaitė Saulius Petrauskas Nerijus Misonis Mantas Kurminas Aleksandras Laucevičius Pranas Šerpytis Medicina octogenarians coronary artery disease coronary artery bypass grafting Percutaneous coronary intervention Background. The data on long-term outcomes for elderly patients with coronary artery disease who undergo invasive treatment is limited. This study aimed to assess long-term outcomes and risk factors for patients over 80 years of age who underwent revascularisation. Methods. This single-centre retrospective study included ≥80-year-old patients who underwent coronary angiography between 2012 and 2014. Among 590 study patients, 411 patients had significant angiographic changes and had either a percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) performed. Baseline patient characteristics, including demographics, comorbidities, survival to hospital discharge, and long term mortality were analysed. Three-year mortality was assessed. Results. Three hundred sixty-nine (89.8%) patients underwent PCI and in 42 (10.2%) CABG was performed. Significant differences between groups were detected in heart failure (PCI – 51.2% vs. CABG – 78.6%; p = 0.001), previous CABG (11.4% vs. 0%; p = 0.014), cardiogenic shock (12.2% vs. 0%; p = 0.008). Hospital mortality rate in the PCI group – 10.6%, CABG – 7.1%; p = 0.787. A median 3-year survival rate in the PCI group – 66.1%, CABG – 66.7%; p = 1.000. Chronic heart failure (OR 2.442; 95% CI: 1.530–3.898, p < 0.001), atrial fibrillation (OR 0.425; 95% CI: 0.261–0.692, p < 0.001), cardiogenic shock (OR 0.120; 95% CI: 0.054–0.270, p = 0.001), and LMCA stenosis (OR 2.104; 95% CI: 1.281–3.456, p = 0.003) were identified as independent 3-year all-cause mortality predictors in multivariate regression analysis. Conclusions. There was no significant difference in hospital mortality and survival rates between elderly patients who underwent PCI or CAGB. The majority of elderly patients underwent a PCI and these patients appeared to experience cardiogenic shock more frequently. 2018 artículo científico 2029-4174 https://www.redalyc.org/articulo.oa?id=694073965002 en http://www.redalyc.org/revista.oa?id=6940 Acta medica Lituanica application/pdf Vilniaus Universitetas Acta medica Lituanica (Lituania) Num.3 Vol.25
title Outcomes of a percutaneous coronary intervention versus coronary artery bypass grafting in octogenarians
topic Medicina
octogenarians
coronary artery disease
coronary artery bypass grafting
Percutaneous coronary intervention
url https://www.redalyc.org/articulo.oa?id=694073965002