Coagulation tests and their association with postoperative blood loss after cardiac surgery with cardiopulmonary bypass
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| Natura: | Artículo científico |
| Lingua: | en |
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Vilniaus Universitetas
2012
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| _version_ | 1876424135741014016 |
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| author | Agnese Ozolina |
| author_facet | Agnese Ozolina |
| contents | Coagulation tests and their association with postoperative blood loss after cardiac surgery with cardiopulmonary bypass Agnese Ozolina Eva Strike Antonina Sondore Indulis Vanags Medicina PT PLT APTT fibrinogen cardiac surgery Background. Platelet count (PLT), activated partial thromboplastin time (APTT), prothrombin time (PT) and fibrinogen are standard coagulation tests used for patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Materials and methods. 83 adult cardiac surgery patients were enrolled into a prospective study. Blood samples for APTT, PT, PLT, fibrinogen were collected preoperatively (T0), on admission to the intensive care unit (T1), 6 and 24 hours postoperatively (T6, T24). 24-hour postoperative blood loss (24h-PBL) was registered. Results. The highest APTT mean value was 47 ± 13 sec at T6, increasing from the baseline by 37%. The lowest mean value of PLT was 140 ± 47 × 109 /L at T24, decreasing from the baseline by 32.5%. PT and fibrinogen mean values at all time points were within the normal range. Correlation with 24h-PBL was shown by T0 and T6 fibrinogen (r = –0.5, r = –0.4, P < 0.0001) and T6 and T24 PLT count (r = –0.25; P = 0.02, r = –0.3; P = 0.01). Conclusions. Marked changes of coagulation tests from standard values after CPB were shown by APTT and PLT. PLT and fibrinogen may have the possible predictive value for greater 24h-PBL. 2012 artículo científico 2029-4174 https://www.redalyc.org/articulo.oa?id=694074047013 en http://www.redalyc.org/revista.oa?id=6940 Acta medica Lituanica application/pdf Vilniaus Universitetas Acta medica Lituanica (Lituania) Num.3 Vol.19 |
| format | Artículo científico |
| id | redalyc_694074047013 |
| institution | Redalyc |
| language | en |
| publishDate | 2012 |
| publisher | Vilniaus Universitetas |
| spellingShingle | Coagulation tests and their association with postoperative blood loss after cardiac surgery with cardiopulmonary bypass Agnese Ozolina Medicina PT PLT APTT fibrinogen cardiac surgery Coagulation tests and their association with postoperative blood loss after cardiac surgery with cardiopulmonary bypass Agnese Ozolina Eva Strike Antonina Sondore Indulis Vanags Medicina PT PLT APTT fibrinogen cardiac surgery Background. Platelet count (PLT), activated partial thromboplastin time (APTT), prothrombin time (PT) and fibrinogen are standard coagulation tests used for patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Materials and methods. 83 adult cardiac surgery patients were enrolled into a prospective study. Blood samples for APTT, PT, PLT, fibrinogen were collected preoperatively (T0), on admission to the intensive care unit (T1), 6 and 24 hours postoperatively (T6, T24). 24-hour postoperative blood loss (24h-PBL) was registered. Results. The highest APTT mean value was 47 ± 13 sec at T6, increasing from the baseline by 37%. The lowest mean value of PLT was 140 ± 47 × 109 /L at T24, decreasing from the baseline by 32.5%. PT and fibrinogen mean values at all time points were within the normal range. Correlation with 24h-PBL was shown by T0 and T6 fibrinogen (r = –0.5, r = –0.4, P < 0.0001) and T6 and T24 PLT count (r = –0.25; P = 0.02, r = –0.3; P = 0.01). Conclusions. Marked changes of coagulation tests from standard values after CPB were shown by APTT and PLT. PLT and fibrinogen may have the possible predictive value for greater 24h-PBL. 2012 artículo científico 2029-4174 https://www.redalyc.org/articulo.oa?id=694074047013 en http://www.redalyc.org/revista.oa?id=6940 Acta medica Lituanica application/pdf Vilniaus Universitetas Acta medica Lituanica (Lituania) Num.3 Vol.19 |
| title | Coagulation tests and their association with postoperative blood loss after cardiac surgery with cardiopulmonary bypass |
| topic | Medicina PT PLT APTT fibrinogen cardiac surgery |
| url | https://www.redalyc.org/articulo.oa?id=694074047013 |