The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG

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Autore principale: Jaqueline Jamara Souza Soares
Natura: Artículo científico
Lingua:en
Pubblicazione: Sociedade Brasileira de Proteção Radiológica - SBPR 2019
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author Jaqueline Jamara Souza Soares
author_facet Jaqueline Jamara Souza Soares
contents The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG Jaqueline Jamara Souza Soares Raynara Maria Silva Jacovone Márcio Henrique Zaim Dalva Lucia Araújo Faria Solange Kazumi Sakata Paulo Souza Santos Biología nanocomposite graphene oxide Functionalization Covalent functionalization of graphene oxide (GO) with polyethylene glycol (PEG) has been widely used in drug delivery systems. This nanocomposite exhibits excellent stability in the presence of high concentrations of salts and proteins and shows low toxicity compared to its raw form. However, it must be sterilized prior to use in medical devices, and for this purpose, the gamma irradiation shows a promising option. Sterilization by ionizing energy through gamma rays, generated by Cobalt-60 self-disintegration, consists in exposing the materials to short electromagnetic waves. The irradiation process provides substantial advantages when compared to thermal and chemical processes, such as, more precise control of the process, lower energy consumption, and less environmental pollution. In this work the effects of gamma radiation on GO and GO functionalized with aminoPEG (GO-PEG-NH2) irradiated with doses (15, 25, 35 and 50 kGy) at rate dose of 7.3 kGy.h1 were evaluated. The analyses were performed by Fourier-transform infrared spectroscopy (FT-IR) and Raman spectroscopy. The results showed that gamma radiation up to 50 kGy did not cause any defects on the nanomaterials. 2019 artículo científico 2319-0612 https://www.redalyc.org/articulo.oa?id=722280899009 en http://www.redalyc.org/revista.oa?id=7222 Brazilian Journal of Radiation Sciences application/pdf Sociedade Brasileira de Proteção Radiológica - SBPR Brazilian Journal of Radiation Sciences (Brasil) Num.3 Vol.7
format Artículo científico
id redalyc_722280899009
institution Redalyc
language en
publishDate 2019
publisher Sociedade Brasileira de Proteção Radiológica - SBPR
spellingShingle The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG
Jaqueline Jamara Souza Soares
Biología
nanocomposite
graphene oxide
Functionalization
The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG Jaqueline Jamara Souza Soares Raynara Maria Silva Jacovone Márcio Henrique Zaim Dalva Lucia Araújo Faria Solange Kazumi Sakata Paulo Souza Santos Biología nanocomposite graphene oxide Functionalization Covalent functionalization of graphene oxide (GO) with polyethylene glycol (PEG) has been widely used in drug delivery systems. This nanocomposite exhibits excellent stability in the presence of high concentrations of salts and proteins and shows low toxicity compared to its raw form. However, it must be sterilized prior to use in medical devices, and for this purpose, the gamma irradiation shows a promising option. Sterilization by ionizing energy through gamma rays, generated by Cobalt-60 self-disintegration, consists in exposing the materials to short electromagnetic waves. The irradiation process provides substantial advantages when compared to thermal and chemical processes, such as, more precise control of the process, lower energy consumption, and less environmental pollution. In this work the effects of gamma radiation on GO and GO functionalized with aminoPEG (GO-PEG-NH2) irradiated with doses (15, 25, 35 and 50 kGy) at rate dose of 7.3 kGy.h1 were evaluated. The analyses were performed by Fourier-transform infrared spectroscopy (FT-IR) and Raman spectroscopy. The results showed that gamma radiation up to 50 kGy did not cause any defects on the nanomaterials. 2019 artículo científico 2319-0612 https://www.redalyc.org/articulo.oa?id=722280899009 en http://www.redalyc.org/revista.oa?id=7222 Brazilian Journal of Radiation Sciences application/pdf Sociedade Brasileira de Proteção Radiológica - SBPR Brazilian Journal of Radiation Sciences (Brasil) Num.3 Vol.7
title The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG
topic Biología
nanocomposite
graphene oxide
Functionalization
url https://www.redalyc.org/articulo.oa?id=722280899009