POTENTIAL HIGH-RISK DRUG-DRUG INTERACTIONS AMONG ELDERLY OUTPATIENTS WITH DEMENTIA: A CROSS-SECTIONAL STUDY
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Sociedade Brasileira de Geriatria e Gerontologia
2015
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| _version_ | 1876426352400269312 |
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| author | Felipe Ferreira |
| author_facet | Felipe Ferreira |
| contents | POTENTIAL HIGH-RISK DRUG-DRUG INTERACTIONS AMONG ELDERLY OUTPATIENTS WITH DEMENTIA: A CROSS-SECTIONAL STUDY Felipe Ferreira Julia Silva Valério Diniz Patrícia Medeiros-Souza Marco Polo Dias Freitas Einstein Francisco Camargos Liana Tieko Evangelista Kusano Leopoldo Luiz dos Santos-Neto Multidisciplinaria (Ciencias Naturales y Exactas) Aged dementia geriatrics drug interactions OBJECTIVE: To analyse the occurrence of potential high-risk drug-drug interactions in elderly individuals with dementia. METHODS: The sample was chosen from a geriatric outpatient clinic of the Multidisciplinary Center for the Elderly in the University Hospital of Brasília. This cross-sectional study included patients aged 60 or older with a diagnosis of dementia. The prescriptions were analyzed using the Lexi-Interact® database to identify possible potential drug-drug interactions. RESULTS: The study included 97 participants. Sixty-one patients (62.9%) had at least one clinically important potential drug-drug interactions (risks C and D). Of the 264 interactions identified, 23 (8.7%) were classified as risk D, 14 were pharmacodynamics and nine pharmacokinetic. CONCLUSION: The results of this study suggest an increased frequency in the occurrence of clinically significant potential drug-drug interactions in dementia patients. This reinforces the need for drug-drug interaction studies in specific populations. 2015 artículo científico 2447-2115 https://www.redalyc.org/articulo.oa?id=739780690005 en http://www.redalyc.org/revista.oa?id=7397 Geriatrics, Gerontology and Aging application/pdf Sociedade Brasileira de Geriatria e Gerontologia Geriatrics, Gerontology and Aging (Brasil) Num.1 Vol.9 |
| format | Artículo científico |
| id | redalyc_739780690005 |
| institution | Redalyc |
| language | en |
| publishDate | 2015 |
| publisher | Sociedade Brasileira de Geriatria e Gerontologia |
| spellingShingle | POTENTIAL HIGH-RISK DRUG-DRUG INTERACTIONS AMONG ELDERLY OUTPATIENTS WITH DEMENTIA: A CROSS-SECTIONAL STUDY Felipe Ferreira Multidisciplinaria (Ciencias Naturales y Exactas) Aged dementia geriatrics drug interactions POTENTIAL HIGH-RISK DRUG-DRUG INTERACTIONS AMONG ELDERLY OUTPATIENTS WITH DEMENTIA: A CROSS-SECTIONAL STUDY Felipe Ferreira Julia Silva Valério Diniz Patrícia Medeiros-Souza Marco Polo Dias Freitas Einstein Francisco Camargos Liana Tieko Evangelista Kusano Leopoldo Luiz dos Santos-Neto Multidisciplinaria (Ciencias Naturales y Exactas) Aged dementia geriatrics drug interactions OBJECTIVE: To analyse the occurrence of potential high-risk drug-drug interactions in elderly individuals with dementia. METHODS: The sample was chosen from a geriatric outpatient clinic of the Multidisciplinary Center for the Elderly in the University Hospital of Brasília. This cross-sectional study included patients aged 60 or older with a diagnosis of dementia. The prescriptions were analyzed using the Lexi-Interact® database to identify possible potential drug-drug interactions. RESULTS: The study included 97 participants. Sixty-one patients (62.9%) had at least one clinically important potential drug-drug interactions (risks C and D). Of the 264 interactions identified, 23 (8.7%) were classified as risk D, 14 were pharmacodynamics and nine pharmacokinetic. CONCLUSION: The results of this study suggest an increased frequency in the occurrence of clinically significant potential drug-drug interactions in dementia patients. This reinforces the need for drug-drug interaction studies in specific populations. 2015 artículo científico 2447-2115 https://www.redalyc.org/articulo.oa?id=739780690005 en http://www.redalyc.org/revista.oa?id=7397 Geriatrics, Gerontology and Aging application/pdf Sociedade Brasileira de Geriatria e Gerontologia Geriatrics, Gerontology and Aging (Brasil) Num.1 Vol.9 |
| title | POTENTIAL HIGH-RISK DRUG-DRUG INTERACTIONS AMONG ELDERLY OUTPATIENTS WITH DEMENTIA: A CROSS-SECTIONAL STUDY |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) Aged dementia geriatrics drug interactions |
| url | https://www.redalyc.org/articulo.oa?id=739780690005 |