CLINICAL AND PATHOLOGICAL MELANOMA DIFFERENCES IN YOUNG AND OLD PEOPLE
Fuente:
Redalyc
Enregistré dans:
| Auteur principal: | |
|---|---|
| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Sociedade Brasileira de Geriatria e Gerontologia
2017
|
| Sujets: | |
| Accès en ligne: | |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
| _version_ | 1876488909410533376 |
|---|---|
| author | Patrick Alexander Wachholz |
| author_facet | Patrick Alexander Wachholz |
| contents | CLINICAL AND PATHOLOGICAL MELANOMA DIFFERENCES IN YOUNG AND OLD PEOPLE Patrick Alexander Wachholz Paula Yoshiko Masuda Ana Cecília Versani Duarte Pinto Multidisciplinaria (Ciencias Naturales y Exactas) aged Melanoma epidemiology BACKGROUND: Melanoma is often misdiagnosed in older people. Some clinical and histopathological features seem to differ according to age. OBJECTIVES: This case series aimed to identify clinicopathological differences of melanoma between older and younger patients. METHODS: We identified all incident melanomas diagnosed in a dermatology outpatients unit from January/2007 to December/2014. Data were collected from medical records and pathology registries. RESULTS: We included 62 patients (mean age of 62.1 ± 4.2 years), with a median Breslow thickness of 4 mm (1.2 − 6.5). While men were majority in the older group, women prevailed between younger counterparts (p = 0.02). Multivariate analysis identified history of chronic sun exposure, multiple naevi, skin phototypes 1 and 2, in situ melanoma and the presence of another skin tumour to be correlated with age. In a logistic regression model, the presence of chronic sun exposure and nodular subtype were found to influence age. Major limitations include those inherent to cross -sectional design, including selection and information biases, the lack of confounding factors analysis (including survival and prognosis), and the sample size. CONCLUSIONS: On this case series, melanoma seems to be more frequent in older men and in elders with chronic sun exposure; age was found to be significantly related to nodular subtype and chronic sun exposure. 2017 otro 2447-2115 https://www.redalyc.org/articulo.oa?id=739780701007 en http://www.redalyc.org/revista.oa?id=7397 Geriatrics, Gerontology and Aging application/pdf Sociedade Brasileira de Geriatria e Gerontologia Geriatrics, Gerontology and Aging (Brasil) Num.2 Vol.11 |
| format | Artículo científico |
| id | redalyc_739780701007 |
| institution | Redalyc |
| language | en |
| publishDate | 2017 |
| publisher | Sociedade Brasileira de Geriatria e Gerontologia |
| spellingShingle | CLINICAL AND PATHOLOGICAL MELANOMA DIFFERENCES IN YOUNG AND OLD PEOPLE Patrick Alexander Wachholz Multidisciplinaria (Ciencias Naturales y Exactas) aged Melanoma epidemiology CLINICAL AND PATHOLOGICAL MELANOMA DIFFERENCES IN YOUNG AND OLD PEOPLE Patrick Alexander Wachholz Paula Yoshiko Masuda Ana Cecília Versani Duarte Pinto Multidisciplinaria (Ciencias Naturales y Exactas) aged Melanoma epidemiology BACKGROUND: Melanoma is often misdiagnosed in older people. Some clinical and histopathological features seem to differ according to age. OBJECTIVES: This case series aimed to identify clinicopathological differences of melanoma between older and younger patients. METHODS: We identified all incident melanomas diagnosed in a dermatology outpatients unit from January/2007 to December/2014. Data were collected from medical records and pathology registries. RESULTS: We included 62 patients (mean age of 62.1 ± 4.2 years), with a median Breslow thickness of 4 mm (1.2 − 6.5). While men were majority in the older group, women prevailed between younger counterparts (p = 0.02). Multivariate analysis identified history of chronic sun exposure, multiple naevi, skin phototypes 1 and 2, in situ melanoma and the presence of another skin tumour to be correlated with age. In a logistic regression model, the presence of chronic sun exposure and nodular subtype were found to influence age. Major limitations include those inherent to cross -sectional design, including selection and information biases, the lack of confounding factors analysis (including survival and prognosis), and the sample size. CONCLUSIONS: On this case series, melanoma seems to be more frequent in older men and in elders with chronic sun exposure; age was found to be significantly related to nodular subtype and chronic sun exposure. 2017 otro 2447-2115 https://www.redalyc.org/articulo.oa?id=739780701007 en http://www.redalyc.org/revista.oa?id=7397 Geriatrics, Gerontology and Aging application/pdf Sociedade Brasileira de Geriatria e Gerontologia Geriatrics, Gerontology and Aging (Brasil) Num.2 Vol.11 |
| title | CLINICAL AND PATHOLOGICAL MELANOMA DIFFERENCES IN YOUNG AND OLD PEOPLE |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) aged Melanoma epidemiology |
| url | https://www.redalyc.org/articulo.oa?id=739780701007 |