Reclassification of the Framingham Risk Score and its Agreement with Other Three Calculations

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Autor principal: Alessandra Santos-Sales
Formato: Artículo científico
Lenguaje:en
Publicado: Universidad de La Sabana 2019
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author Alessandra Santos-Sales
author_facet Alessandra Santos-Sales
contents Reclassification of the Framingham Risk Score and its Agreement with Other Three Calculations Alessandra Santos-Sales Cezar Augusto Casotti Medicina mortality morbidity epidemiology Cardiovascular diseases epidemiological studies Objective: To investigate the concordance between the modified Framingham score using the ankle-brachial index and the high-sensitivity C-reactive protein with the other scores. Materials and method: Cross-sectional study nested with a cohort, with elderly population, from January to March, 2018. The population characterization was presented as mean, median, absolute and relative frequencies according to degree of normality. The Kappa concordance of the modified Framingham score was calculated with the Framingham score itself, with the Systematic Coronary Risk Evaluation (Score) and with the Prospective Cardiovascular Munster (Procam). Results: The modified Framingham score shows moderate Kappa concordance with the Framingham score and the Score (p < 0.001), but weak with Procam. The ultra-sensitive C-reactive protein presented more reclassification of individuals among risk strata than the ankle-brachial index. Conclusions: The Framingham score modified with the Framingham score itself, and then with the Score obtained a higher proportion of concordant cases in the high-risk stratum. High-sensitivity C-reactive protein and the ankle-brachial index modify cardiovascular risk as emerging factors to provide an accurate risk stratification and to infer better management of the therapy. Thus, the Framingham score with its reclassification is the best screening tool for cardiovascular risk. 2019 artículo científico 1657-5997 https://www.redalyc.org/articulo.oa?id=74160595009 https://www.redalyc.org/journal/741/74160595009/ https://www.redalyc.org/journal/741/74160595009/html/ https://www.redalyc.org/journal/741/74160595009/74160595009.epub https://www.redalyc.org/journal/741/74160595009/movil 10.5294/aqui.2019.19.2.9 en http://www.redalyc.org/revista.oa?id=741 Aquichan application/pdf Universidad de La Sabana Aquichan (Colombia) Num.2 Vol.19
format Artículo científico
id redalyc_74160595009
institution Redalyc
language en
publishDate 2019
publisher Universidad de La Sabana
spellingShingle Reclassification of the Framingham Risk Score and its Agreement with Other Three Calculations
Alessandra Santos-Sales
Medicina
mortality
morbidity
epidemiology
Cardiovascular diseases
epidemiological studies
Reclassification of the Framingham Risk Score and its Agreement with Other Three Calculations Alessandra Santos-Sales Cezar Augusto Casotti Medicina mortality morbidity epidemiology Cardiovascular diseases epidemiological studies Objective: To investigate the concordance between the modified Framingham score using the ankle-brachial index and the high-sensitivity C-reactive protein with the other scores. Materials and method: Cross-sectional study nested with a cohort, with elderly population, from January to March, 2018. The population characterization was presented as mean, median, absolute and relative frequencies according to degree of normality. The Kappa concordance of the modified Framingham score was calculated with the Framingham score itself, with the Systematic Coronary Risk Evaluation (Score) and with the Prospective Cardiovascular Munster (Procam). Results: The modified Framingham score shows moderate Kappa concordance with the Framingham score and the Score (p < 0.001), but weak with Procam. The ultra-sensitive C-reactive protein presented more reclassification of individuals among risk strata than the ankle-brachial index. Conclusions: The Framingham score modified with the Framingham score itself, and then with the Score obtained a higher proportion of concordant cases in the high-risk stratum. High-sensitivity C-reactive protein and the ankle-brachial index modify cardiovascular risk as emerging factors to provide an accurate risk stratification and to infer better management of the therapy. Thus, the Framingham score with its reclassification is the best screening tool for cardiovascular risk. 2019 artículo científico 1657-5997 https://www.redalyc.org/articulo.oa?id=74160595009 https://www.redalyc.org/journal/741/74160595009/ https://www.redalyc.org/journal/741/74160595009/html/ https://www.redalyc.org/journal/741/74160595009/74160595009.epub https://www.redalyc.org/journal/741/74160595009/movil 10.5294/aqui.2019.19.2.9 en http://www.redalyc.org/revista.oa?id=741 Aquichan application/pdf Universidad de La Sabana Aquichan (Colombia) Num.2 Vol.19
title Reclassification of the Framingham Risk Score and its Agreement with Other Three Calculations
topic Medicina
mortality
morbidity
epidemiology
Cardiovascular diseases
epidemiological studies
url https://www.redalyc.org/articulo.oa?id=74160595009
https://www.redalyc.org/journal/741/74160595009/
https://www.redalyc.org/journal/741/74160595009/html/
https://www.redalyc.org/journal/741/74160595009/74160595009.epub
https://www.redalyc.org/journal/741/74160595009/movil