Animal Model of Cognitive Decline and Neural Transplantation of Stem Cells as a Prospective Therapy
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| Format: | Artículo científico |
| Langue: | en |
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Universidad del Rosario
2017
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| _version_ | 1876466691246915584 |
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| author | Leticia Domingues Bertuzzi |
| author_facet | Leticia Domingues Bertuzzi |
| contents | Animal Model of Cognitive Decline and Neural Transplantation of Stem Cells as a Prospective Therapy Leticia Domingues Bertuzzi Patricia Santos da Silva Élida Fluck Pereira Neto Rafael Nicolaidis Alcyr Alves de Oliveira Jr Psicología Alzheimer’s disease stem cell based therapy Animal models of cognitive decline There are few animal models of cognitive decline that could be considered as prominent as the cholinergic lesion model of Alzheimer’s disease. Alzheimer’s disease is a neurodegenerative disorder associated with aging with accentuated progressive cognitive impairment. Its multiple complex sequential and interactive neural pathways may lead to the understanding that a single agent intervention might be insufficient to impact the course of this disease. The current pharmacological treatment is palliative and, although it may slow down the disease’s progression, it still cannot offer cure. The combination of drugs and antioxidant substances has been investigated, nevertheless there are few studies demonstrating optimal and consistent results based on this combination. Thus, the purpose of this paper is to highlight cell-based therapies as prospective treatment of peripheral and central nervous system disorders. 2017 artículo científico 1794-4724 https://www.redalyc.org/articulo.oa?id=79949625013 en http://www.redalyc.org/revista.oa?id=799 Avances en Psicología Latinoamericana application/pdf Universidad del Rosario Avances en Psicología Latinoamericana (Colombia) Num.1 Vol.35 |
| format | Artículo científico |
| id | redalyc_79949625013 |
| institution | Redalyc |
| language | en |
| publishDate | 2017 |
| publisher | Universidad del Rosario |
| spellingShingle | Animal Model of Cognitive Decline and Neural Transplantation of Stem Cells as a Prospective Therapy Leticia Domingues Bertuzzi Psicología Alzheimer’s disease stem cell based therapy Animal models of cognitive decline Animal Model of Cognitive Decline and Neural Transplantation of Stem Cells as a Prospective Therapy Leticia Domingues Bertuzzi Patricia Santos da Silva Élida Fluck Pereira Neto Rafael Nicolaidis Alcyr Alves de Oliveira Jr Psicología Alzheimer’s disease stem cell based therapy Animal models of cognitive decline There are few animal models of cognitive decline that could be considered as prominent as the cholinergic lesion model of Alzheimer’s disease. Alzheimer’s disease is a neurodegenerative disorder associated with aging with accentuated progressive cognitive impairment. Its multiple complex sequential and interactive neural pathways may lead to the understanding that a single agent intervention might be insufficient to impact the course of this disease. The current pharmacological treatment is palliative and, although it may slow down the disease’s progression, it still cannot offer cure. The combination of drugs and antioxidant substances has been investigated, nevertheless there are few studies demonstrating optimal and consistent results based on this combination. Thus, the purpose of this paper is to highlight cell-based therapies as prospective treatment of peripheral and central nervous system disorders. 2017 artículo científico 1794-4724 https://www.redalyc.org/articulo.oa?id=79949625013 en http://www.redalyc.org/revista.oa?id=799 Avances en Psicología Latinoamericana application/pdf Universidad del Rosario Avances en Psicología Latinoamericana (Colombia) Num.1 Vol.35 |
| title | Animal Model of Cognitive Decline and Neural Transplantation of Stem Cells as a Prospective Therapy |
| topic | Psicología Alzheimer’s disease stem cell based therapy Animal models of cognitive decline |
| url | https://www.redalyc.org/articulo.oa?id=79949625013 |