Characterization of Retinoblastoma Patients in a Referral Center on the Colombian North Coast

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Main Author: ANA MARÍA ÁLVAREZ CASTILLO
Format: Artículo científico
Language:en
Published: Universidad del Norte 2024
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author ANA MARÍA ÁLVAREZ CASTILLO
author_facet ANA MARÍA ÁLVAREZ CASTILLO
contents Characterization of Retinoblastoma Patients in a Referral Center on the Colombian North Coast ANA MARÍA ÁLVAREZ CASTILLO CESAR ATENCIA NIÑO DIANA CIFUENTES ZAPATA KATIA GUTIÉRREZ BRUN JAIME MORENO CHAPARRO JAVIER ANTONIO AMAYA NIETO JAVIER VÁSQUEZ RAMÍREZ Salud Colombia Treatment Ophthalmology Retinoblastoma Intraarterial Chemotherapy Purpose: The purpose of the following study was to describe the sociodemographic, clinical, and therapeutic characteristics of patients with retinoblastoma (RB), the most common intraocular tumor in children, receiving medical care in an eyecare institution in the Caribbean region of Colombia.Methods: A case series between 2016 and 2021 was carried out. Eyes of patients with RB, receiving medical care in a single health care institution, and in compliance with the established follow-up protocol, were included. Descriptive analyzes of relevant variables were performed.Results: In this study, a total of 21 eyes of 16 patients were examined. The average age at the time of diagnosis was 17.7 months, and 50% of children were male. Using the International Classification for Intraocular Retinoblastoma, 42.9% of the total cases were classified as group D. Out of the 21 cases, 71.4% went into total remission without the necessity for enucleation, and the most common treatment was chemotherapy, using Melphalan® via intraarterial or intravitreal administration.Conclusion: Specific findings of patients with RB in the Caribbean Coast of Colombia were identified. These findings imply that, despite the obstacles to healthcare access, an early diagnosis and a treatment plan using intraarterial chemotherapy may provide a satisfactory clinical outcome (remission). 2024 artículo científico 0120-5552 https://www.redalyc.org/articulo.oa?id=81782332007 https://www.redalyc.org/journal/817/81782332007/ https://www.redalyc.org/journal/817/81782332007/html/ https://www.redalyc.org/journal/817/81782332007/81782332007.epub https://www.redalyc.org/journal/817/81782332007/movil 10.14482/sun.40.01.345.916 en http://www.redalyc.org/revista.oa?id=817 Salud Uninorte application/pdf Universidad del Norte Salud Uninorte (Colombia) Num.1 Vol.40
format Artículo científico
id redalyc_81782332007
institution Redalyc
language en
publishDate 2024
publisher Universidad del Norte
spellingShingle Characterization of Retinoblastoma Patients in a Referral Center on the Colombian North Coast
ANA MARÍA ÁLVAREZ CASTILLO
Salud
Colombia
Treatment
Ophthalmology
Retinoblastoma
Intraarterial Chemotherapy
Characterization of Retinoblastoma Patients in a Referral Center on the Colombian North Coast ANA MARÍA ÁLVAREZ CASTILLO CESAR ATENCIA NIÑO DIANA CIFUENTES ZAPATA KATIA GUTIÉRREZ BRUN JAIME MORENO CHAPARRO JAVIER ANTONIO AMAYA NIETO JAVIER VÁSQUEZ RAMÍREZ Salud Colombia Treatment Ophthalmology Retinoblastoma Intraarterial Chemotherapy Purpose: The purpose of the following study was to describe the sociodemographic, clinical, and therapeutic characteristics of patients with retinoblastoma (RB), the most common intraocular tumor in children, receiving medical care in an eyecare institution in the Caribbean region of Colombia.Methods: A case series between 2016 and 2021 was carried out. Eyes of patients with RB, receiving medical care in a single health care institution, and in compliance with the established follow-up protocol, were included. Descriptive analyzes of relevant variables were performed.Results: In this study, a total of 21 eyes of 16 patients were examined. The average age at the time of diagnosis was 17.7 months, and 50% of children were male. Using the International Classification for Intraocular Retinoblastoma, 42.9% of the total cases were classified as group D. Out of the 21 cases, 71.4% went into total remission without the necessity for enucleation, and the most common treatment was chemotherapy, using Melphalan® via intraarterial or intravitreal administration.Conclusion: Specific findings of patients with RB in the Caribbean Coast of Colombia were identified. These findings imply that, despite the obstacles to healthcare access, an early diagnosis and a treatment plan using intraarterial chemotherapy may provide a satisfactory clinical outcome (remission). 2024 artículo científico 0120-5552 https://www.redalyc.org/articulo.oa?id=81782332007 https://www.redalyc.org/journal/817/81782332007/ https://www.redalyc.org/journal/817/81782332007/html/ https://www.redalyc.org/journal/817/81782332007/81782332007.epub https://www.redalyc.org/journal/817/81782332007/movil 10.14482/sun.40.01.345.916 en http://www.redalyc.org/revista.oa?id=817 Salud Uninorte application/pdf Universidad del Norte Salud Uninorte (Colombia) Num.1 Vol.40
title Characterization of Retinoblastoma Patients in a Referral Center on the Colombian North Coast
topic Salud
Colombia
Treatment
Ophthalmology
Retinoblastoma
Intraarterial Chemotherapy
url https://www.redalyc.org/articulo.oa?id=81782332007
https://www.redalyc.org/journal/817/81782332007/
https://www.redalyc.org/journal/817/81782332007/html/
https://www.redalyc.org/journal/817/81782332007/81782332007.epub
https://www.redalyc.org/journal/817/81782332007/movil