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| Format: | Artículo científico |
| Language: | en |
| Published: |
Instituto Nacional de Salud
2004
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| Online Access: | https://www.redalyc.org/articulo.oa?id=84309823 |
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| _version_ | 1866568524712902656 |
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| author | Wellman Ribón |
| author_facet | Wellman Ribón |
| contents | Molecular epidemiology of tuberculosis: methodology and applications Wellman Ribón Marcos V. Burgos Juan Camilo Méndez Medicina methods genotype tuberculosis drug effects pathogenicity The resurgence of tuberculosis around the world has renewed interest in understanding theepidemiology and pathogenesis of this disease. A revolutionary advance in the field oftuberculosis research has been the development of molecular techniques that permitidentification and tracking of individual strains of Mycobacterium tuberculosis. With thesetechniques, molecular epidemiology has been established as a new discipline that adds anotherdimension to the classical epidemiology of tuberculosis and has increased our understandingof the transmission dynamics of M. tuberculosis. The increased epidemiological knowledge hasled to discovery of inadequacies in tuberculosis control programs; this information has helpedgarner resources for program improvement and has highlighted the need for the continuoussurveillance of tuberculosis. Additional genetic methods are being developed based on theknowledge of the genome sequence of M. tuberculosis. These simpler and less costly genotypingtechniques promise to expand the application of molecular epidemiology to developing nations(where 90% of the disease burden occurs) in support of national tuberculosis programs.Furthermore, these tools permit ever more effective probes into the dynamics of transmission,the population structure, evolution and pathogenesis of M. tuberculosis 2004 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84309823 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.Su1 Vol.24 |
| format | Artículo científico |
| id | redalyc_84309823 |
| language | en |
| publishDate | 2004 |
| publisher | Instituto Nacional de Salud |
| spellingShingle | Molecular epidemiology of tuberculosis: methodology and applications Wellman Ribón Medicina methods genotype tuberculosis drug effects pathogenicity Molecular epidemiology of tuberculosis: methodology and applications Wellman Ribón Marcos V. Burgos Juan Camilo Méndez Medicina methods genotype tuberculosis drug effects pathogenicity The resurgence of tuberculosis around the world has renewed interest in understanding theepidemiology and pathogenesis of this disease. A revolutionary advance in the field oftuberculosis research has been the development of molecular techniques that permitidentification and tracking of individual strains of Mycobacterium tuberculosis. With thesetechniques, molecular epidemiology has been established as a new discipline that adds anotherdimension to the classical epidemiology of tuberculosis and has increased our understandingof the transmission dynamics of M. tuberculosis. The increased epidemiological knowledge hasled to discovery of inadequacies in tuberculosis control programs; this information has helpedgarner resources for program improvement and has highlighted the need for the continuoussurveillance of tuberculosis. Additional genetic methods are being developed based on theknowledge of the genome sequence of M. tuberculosis. These simpler and less costly genotypingtechniques promise to expand the application of molecular epidemiology to developing nations(where 90% of the disease burden occurs) in support of national tuberculosis programs.Furthermore, these tools permit ever more effective probes into the dynamics of transmission,the population structure, evolution and pathogenesis of M. tuberculosis 2004 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84309823 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.Su1 Vol.24 |
| title | Molecular epidemiology of tuberculosis: methodology and applications |
| topic | Medicina methods genotype tuberculosis drug effects pathogenicity |
| url | https://www.redalyc.org/articulo.oa?id=84309823 |