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| Format: | Artículo científico |
| Language: | en |
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Instituto Nacional de Salud
2000
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| Online Access: | https://www.redalyc.org/articulo.oa?id=84320105 |
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| _version_ | 1866587536274489344 |
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| author | Henry Ostos |
| author_facet | Henry Ostos |
| contents | Disminución de la incidencia de defectos de cierre del tubo neural en el Hospital Universitario de Neiva: posible efecto de la promoción del consumo de ácido fólico Henry Ostos Gilberto Astaiza Miller Bautista Favio Rojas Antonio Bermúdez Francisco García Medicina folate neural genetic congenital prevention Neural tube defects (NTD) are brain or spinal cord congenital defects, causing death orsevere disability Causes of NTDs are unknown. It seems that NTDs occur due to environmentaland genetic interactions. ln 1997, a significant increase in the rate of NTDs (p=0.035)related to 1996 was obse~ed in the maternity wing at the University Hospital in Neiva,Colombia. Health authorities initiated a program according to the universal recommendationabout folic acid supplementation and fortification to prevent NTDs (CDC Folic AcidResource Guide). The aim of this study was to measure the incidence of NTDs in 1998,related to previous years, as a possible way to measure the impact of the actions adoptedby the community and health authorities. The incidence of NTDs, Down syndrome, cleft or palate lip, stillbirth and fetal losses, was measured for 1998. The rate of NTDs wassimilar compared to that of Latin America (p=0.526), but significantly less than that for1997 (p=0.024), and reached similar values than those of 1996 (p=0.807). The explanationfor this reduction of NTDs is not clear now, but we conclude that there is an apparentimpact of advice on preconceptional folic acid supplementation together with improvementin dietary intake through grain and flour fortification. We recommend to evaluate theattitudes and practices of childbearing women regarding the benefits of folic acid beforeconception and during pregnancy. It is also important to continue the surveillance programfor NTDs 2000 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84320105 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.1 Vol.20 |
| format | Artículo científico |
| id | redalyc_84320105 |
| language | en |
| publishDate | 2000 |
| publisher | Instituto Nacional de Salud |
| spellingShingle | Disminución de la incidencia de defectos de cierre del tubo neural en el Hospital Universitario de Neiva: posible efecto de la promoción del consumo de ácido fólico Henry Ostos Medicina folate neural genetic congenital prevention Disminución de la incidencia de defectos de cierre del tubo neural en el Hospital Universitario de Neiva: posible efecto de la promoción del consumo de ácido fólico Henry Ostos Gilberto Astaiza Miller Bautista Favio Rojas Antonio Bermúdez Francisco García Medicina folate neural genetic congenital prevention Neural tube defects (NTD) are brain or spinal cord congenital defects, causing death orsevere disability Causes of NTDs are unknown. It seems that NTDs occur due to environmentaland genetic interactions. ln 1997, a significant increase in the rate of NTDs (p=0.035)related to 1996 was obse~ed in the maternity wing at the University Hospital in Neiva,Colombia. Health authorities initiated a program according to the universal recommendationabout folic acid supplementation and fortification to prevent NTDs (CDC Folic AcidResource Guide). The aim of this study was to measure the incidence of NTDs in 1998,related to previous years, as a possible way to measure the impact of the actions adoptedby the community and health authorities. The incidence of NTDs, Down syndrome, cleft or palate lip, stillbirth and fetal losses, was measured for 1998. The rate of NTDs wassimilar compared to that of Latin America (p=0.526), but significantly less than that for1997 (p=0.024), and reached similar values than those of 1996 (p=0.807). The explanationfor this reduction of NTDs is not clear now, but we conclude that there is an apparentimpact of advice on preconceptional folic acid supplementation together with improvementin dietary intake through grain and flour fortification. We recommend to evaluate theattitudes and practices of childbearing women regarding the benefits of folic acid beforeconception and during pregnancy. It is also important to continue the surveillance programfor NTDs 2000 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84320105 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.1 Vol.20 |
| title | Disminución de la incidencia de defectos de cierre del tubo neural en el Hospital Universitario de Neiva: posible efecto de la promoción del consumo de ácido fólico |
| topic | Medicina folate neural genetic congenital prevention |
| url | https://www.redalyc.org/articulo.oa?id=84320105 |