Acción de algunos biocidas sobre las micobacterias no tuberculosas
Fuente:
Redalyc
Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
Instituto Nacional de Salud
2002
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1876468004563189760 |
|---|---|
| author | Yenny Patricia Pardo |
| author_facet | Yenny Patricia Pardo |
| contents | Acción de algunos biocidas sobre las micobacterias no tuberculosas Yenny Patricia Pardo Claudia Ximena Ramírez Clara Inés León Medicina NTM biosafety desinfection mycobacteria The incidence of disease and nosocomial infections produced by non tuberculosis mycobacteria(NTM) has increased in immunocompetent patients, but also and more frequently, inimmunosupressed patients. Several studies have disclosed that mycobacteria are more resistantto biocides than non-sporulating bacteria; in addition, some species are particularly resistant.The biocide action of sodium hypochloride and glutaraldehyde on Mycobacterium aviumintracellulare,Mycobacterium gordonae, Mycobacterium fortuitum and Mycobacterium chelonaewas studied, using a modified Kelsey Maurer test. For the different species, both the minimalinhibitory concentration (MIC) and the minimal action time were determined. Effectiveness ofsodium hypochloride and glutaraldehyde against the different mycobacterial species varied.The same was true for different isolates of the same species. Sodium hypochloride effectiveMIC and exposure time (killing of 99.99% of all NTM) were 0.2% and 5 minutes, respectively. Inorder to achieve 100% killing, 0.5% MIC and 15 minute exposure were needed. In the case ofglutaraldehyde, 99.99% of the bacteria were killed with 1% MIC and a 15 minute exposure. Aneffectiveness of 100% was achieved with a 2% MIC of glutaraldehyde and a 15 minute exposure.Sodium hypochloride and glutaraldehyde are effective biocides for mycobacteria. The first biocideis cheap and effective at low concentrations, but its corrosive and oxidant nature makes itimpossible for use in hospitals or with laboratory equipment. Glutaraldehyde (neither corrosive nor oxidant) is a safe alternative for disinfection of this type of equipment. However, it is importantto bear in mind that these pathogens may develop resistance to biocides. 2002 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84322208 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.2 Vol.22 |
| format | Artículo científico |
| id | redalyc_84322208 |
| institution | Redalyc |
| language | en |
| publishDate | 2002 |
| publisher | Instituto Nacional de Salud |
| spellingShingle | Acción de algunos biocidas sobre las micobacterias no tuberculosas Yenny Patricia Pardo Medicina NTM biosafety desinfection mycobacteria Acción de algunos biocidas sobre las micobacterias no tuberculosas Yenny Patricia Pardo Claudia Ximena Ramírez Clara Inés León Medicina NTM biosafety desinfection mycobacteria The incidence of disease and nosocomial infections produced by non tuberculosis mycobacteria(NTM) has increased in immunocompetent patients, but also and more frequently, inimmunosupressed patients. Several studies have disclosed that mycobacteria are more resistantto biocides than non-sporulating bacteria; in addition, some species are particularly resistant.The biocide action of sodium hypochloride and glutaraldehyde on Mycobacterium aviumintracellulare,Mycobacterium gordonae, Mycobacterium fortuitum and Mycobacterium chelonaewas studied, using a modified Kelsey Maurer test. For the different species, both the minimalinhibitory concentration (MIC) and the minimal action time were determined. Effectiveness ofsodium hypochloride and glutaraldehyde against the different mycobacterial species varied.The same was true for different isolates of the same species. Sodium hypochloride effectiveMIC and exposure time (killing of 99.99% of all NTM) were 0.2% and 5 minutes, respectively. Inorder to achieve 100% killing, 0.5% MIC and 15 minute exposure were needed. In the case ofglutaraldehyde, 99.99% of the bacteria were killed with 1% MIC and a 15 minute exposure. Aneffectiveness of 100% was achieved with a 2% MIC of glutaraldehyde and a 15 minute exposure.Sodium hypochloride and glutaraldehyde are effective biocides for mycobacteria. The first biocideis cheap and effective at low concentrations, but its corrosive and oxidant nature makes itimpossible for use in hospitals or with laboratory equipment. Glutaraldehyde (neither corrosive nor oxidant) is a safe alternative for disinfection of this type of equipment. However, it is importantto bear in mind that these pathogens may develop resistance to biocides. 2002 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84322208 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.2 Vol.22 |
| title | Acción de algunos biocidas sobre las micobacterias no tuberculosas |
| topic | Medicina NTM biosafety desinfection mycobacteria |
| url | https://www.redalyc.org/articulo.oa?id=84322208 |