Síndrome hemofagocítico asociado con dengue hemorrágico
Fuente:
Redalyc
Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
Instituto Nacional de Salud
2002
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1876454586340868096 |
|---|---|
| author | Ernesto Rueda |
| author_facet | Ernesto Rueda |
| contents | Síndrome hemofagocítico asociado con dengue hemorrágico Ernesto Rueda Ángela Méndez Gerardo González Medicina dengue haemophagocytosis dengue haemorrhagic fever The haemophagocytic syndrome is characterised by systemic proliferation of non-neoplastichistiocytes showing haemophagocytosis resulting in blood cytopaenia. It has been described inrelation to several viruses earlier. We present three patients with haemophagocytic syndrome (HFS)secondary to dengue haemorrhagic fever (DHF) confirmed by standard laboratory tests. The patientswere hospitalized at the University Hospital (Hospital Universitario Ramon Gonzalez Valencia-HURGV)in Bucaramanga, Colombia, during the past two years. They were all school-aged patients whopresented DHF with intense abdominal pain, prolonged fever, hypotension and painful hepatomegaly.Laboratory tests showed thrombocitopenia, anaemia and leucopenia. A calculous cholecystitis wasobserved in the abdominal ultrasonography, and all bone marrow aspirations showed that platelets,red and white blood cells were phagocyted by histiocites. According to the International Society ofHistiocytosis, SHF is defined and classified in three major categories; the reported cases correspondedto histiocytosis class II, specifically to secondary SHF. Diverse associations of this syndromecorrespond to viral infections and some other non-infectious diseases. A difference has beenestablished between primary SHF and secondary SHF. Finally, we emphasize that these threepatients had an atypical evolution of FHD, being prolonged fever and persistent abdominal pain themost important symptoms.The authors recommend that a bone marrow aspiration should be carriedout as part of the differential diagnosis study in prolonged fever associated with dengue, as there isa possibility that this complication could be secondary SHF 2002 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84322211 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.2 Vol.22 |
| format | Artículo científico |
| id | redalyc_84322211 |
| institution | Redalyc |
| language | en |
| publishDate | 2002 |
| publisher | Instituto Nacional de Salud |
| spellingShingle | Síndrome hemofagocítico asociado con dengue hemorrágico Ernesto Rueda Medicina dengue haemophagocytosis dengue haemorrhagic fever Síndrome hemofagocítico asociado con dengue hemorrágico Ernesto Rueda Ángela Méndez Gerardo González Medicina dengue haemophagocytosis dengue haemorrhagic fever The haemophagocytic syndrome is characterised by systemic proliferation of non-neoplastichistiocytes showing haemophagocytosis resulting in blood cytopaenia. It has been described inrelation to several viruses earlier. We present three patients with haemophagocytic syndrome (HFS)secondary to dengue haemorrhagic fever (DHF) confirmed by standard laboratory tests. The patientswere hospitalized at the University Hospital (Hospital Universitario Ramon Gonzalez Valencia-HURGV)in Bucaramanga, Colombia, during the past two years. They were all school-aged patients whopresented DHF with intense abdominal pain, prolonged fever, hypotension and painful hepatomegaly.Laboratory tests showed thrombocitopenia, anaemia and leucopenia. A calculous cholecystitis wasobserved in the abdominal ultrasonography, and all bone marrow aspirations showed that platelets,red and white blood cells were phagocyted by histiocites. According to the International Society ofHistiocytosis, SHF is defined and classified in three major categories; the reported cases correspondedto histiocytosis class II, specifically to secondary SHF. Diverse associations of this syndromecorrespond to viral infections and some other non-infectious diseases. A difference has beenestablished between primary SHF and secondary SHF. Finally, we emphasize that these threepatients had an atypical evolution of FHD, being prolonged fever and persistent abdominal pain themost important symptoms.The authors recommend that a bone marrow aspiration should be carriedout as part of the differential diagnosis study in prolonged fever associated with dengue, as there isa possibility that this complication could be secondary SHF 2002 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84322211 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.2 Vol.22 |
| title | Síndrome hemofagocítico asociado con dengue hemorrágico |
| topic | Medicina dengue haemophagocytosis dengue haemorrhagic fever |
| url | https://www.redalyc.org/articulo.oa?id=84322211 |