Phenotypic and genotypic characterization of Neisseria meningitidis serogroup B isolates from Cartagena, Colombia, 2012-2014
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| Format: | Artículo científico |
| Sprache: | en |
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Instituto Nacional de Salud
2015
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| _version_ | 1876485544109670400 |
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| author | Jaime Moreno |
| author_facet | Jaime Moreno |
| contents | Phenotypic and genotypic characterization of Neisseria meningitidis serogroup B isolates from Cartagena, Colombia, 2012-2014 Jaime Moreno Olga Sanabria Sandra Yamile Saavedra Karina Rodríguez Carolina Duarte Medicina phenotype meningitis serogroup B Neisseria meningitidis Introduction: Neisseria meningitidis is one of the leading causes of bacterial meningitis. In 2013, an increase in invasive disease caused by N. meningitidis serogroup B occurred in Cartagena, Colombia. Objective: The aim of this study was to characterize serogroup B isolates recovered from patients with meningococcal meningitis in Cartagena during 2012 and 2014. Materials and methods: Twenty-five isolates were collected through a national, laboratory-based surveillance, and phenotypic and genotypic characteristics were determined by serosubtyping, serotyping, antimicrobial susceptibility testing, repetitive sequence-based PCR (rep-PCR). MLST data available were also used. Results: The B:10,15:nt phenotype, associated with clonal complex ST-41/44, was responsible for 68.0% of all cases. Conclusion: The clinical, epidemiological and molecular characterization of meningococcal disease is necessary for understanding the spread of virulent meningococcal clones and for facilitating the early detection of cases to reduce epidemic risks. 2015 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84338617017 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.1 Vol.35 |
| format | Artículo científico |
| id | redalyc_84338617017 |
| institution | Redalyc |
| language | en |
| publishDate | 2015 |
| publisher | Instituto Nacional de Salud |
| spellingShingle | Phenotypic and genotypic characterization of Neisseria meningitidis serogroup B isolates from Cartagena, Colombia, 2012-2014 Jaime Moreno Medicina phenotype meningitis serogroup B Neisseria meningitidis Phenotypic and genotypic characterization of Neisseria meningitidis serogroup B isolates from Cartagena, Colombia, 2012-2014 Jaime Moreno Olga Sanabria Sandra Yamile Saavedra Karina Rodríguez Carolina Duarte Medicina phenotype meningitis serogroup B Neisseria meningitidis Introduction: Neisseria meningitidis is one of the leading causes of bacterial meningitis. In 2013, an increase in invasive disease caused by N. meningitidis serogroup B occurred in Cartagena, Colombia. Objective: The aim of this study was to characterize serogroup B isolates recovered from patients with meningococcal meningitis in Cartagena during 2012 and 2014. Materials and methods: Twenty-five isolates were collected through a national, laboratory-based surveillance, and phenotypic and genotypic characteristics were determined by serosubtyping, serotyping, antimicrobial susceptibility testing, repetitive sequence-based PCR (rep-PCR). MLST data available were also used. Results: The B:10,15:nt phenotype, associated with clonal complex ST-41/44, was responsible for 68.0% of all cases. Conclusion: The clinical, epidemiological and molecular characterization of meningococcal disease is necessary for understanding the spread of virulent meningococcal clones and for facilitating the early detection of cases to reduce epidemic risks. 2015 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84338617017 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.1 Vol.35 |
| title | Phenotypic and genotypic characterization of Neisseria meningitidis serogroup B isolates from Cartagena, Colombia, 2012-2014 |
| topic | Medicina phenotype meningitis serogroup B Neisseria meningitidis |
| url | https://www.redalyc.org/articulo.oa?id=84338617017 |