Inmunohistochemical detection of pandemic SARS-CoV-2 antigens in lung tissue

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Autore principale: Jorge Rivera
Natura: Artículo científico
Lingua:en
Pubblicazione: Instituto Nacional de Salud 2022
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author Jorge Rivera
author_facet Jorge Rivera
contents Inmunohistochemical detection of pandemic SARS-CoV-2 antigens in lung tissue Jorge Rivera Sheryll Corchuelo Edgar Parra Eugenio Aladino Meek Marcela Mercado Orlando Torres-Fernández Medicina 19 lung COVID viral antigens The COVID-19 pandemic caused by the SARS-CoV-2 virus has generated globally more than 110.7 million infections and 2.4 million deaths. The severity of this infection can range from asymptomatic, mild to severe.To know the possible associations between the presence of the virus and histopathological alterations found in tissues of fatal cases of COVID-19, the presence of the virus in the lung tissue of a patient with a clinical history of SARS-CoV-2 infection was evaluated.Lung tissue was histologically processed for immunohistochemical detection of SARS- CoV-2. In the histopathological study, morphological changes associated with pneumonitis of viral origin were observed. Likewise, the location of the SARS-CoV-2 virus was observed mainly in the cytoplasm of the cells of the inflammatory infiltrate. 2022 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84373566002 https://www.redalyc.org/journal/843/84373566002/ https://www.redalyc.org/journal/843/84373566002/html/ https://www.redalyc.org/journal/843/84373566002/84373566002.epub https://www.redalyc.org/journal/843/84373566002/movil 10.7705/biomedica.6132 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.Sp. 2 Vol.42
format Artículo científico
id redalyc_84373566002
institution Redalyc
language en
publishDate 2022
publisher Instituto Nacional de Salud
spellingShingle Inmunohistochemical detection of pandemic SARS-CoV-2 antigens in lung tissue
Jorge Rivera
Medicina
19
lung
COVID
viral
antigens
Inmunohistochemical detection of pandemic SARS-CoV-2 antigens in lung tissue Jorge Rivera Sheryll Corchuelo Edgar Parra Eugenio Aladino Meek Marcela Mercado Orlando Torres-Fernández Medicina 19 lung COVID viral antigens The COVID-19 pandemic caused by the SARS-CoV-2 virus has generated globally more than 110.7 million infections and 2.4 million deaths. The severity of this infection can range from asymptomatic, mild to severe.To know the possible associations between the presence of the virus and histopathological alterations found in tissues of fatal cases of COVID-19, the presence of the virus in the lung tissue of a patient with a clinical history of SARS-CoV-2 infection was evaluated.Lung tissue was histologically processed for immunohistochemical detection of SARS- CoV-2. In the histopathological study, morphological changes associated with pneumonitis of viral origin were observed. Likewise, the location of the SARS-CoV-2 virus was observed mainly in the cytoplasm of the cells of the inflammatory infiltrate. 2022 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84373566002 https://www.redalyc.org/journal/843/84373566002/ https://www.redalyc.org/journal/843/84373566002/html/ https://www.redalyc.org/journal/843/84373566002/84373566002.epub https://www.redalyc.org/journal/843/84373566002/movil 10.7705/biomedica.6132 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.Sp. 2 Vol.42
title Inmunohistochemical detection of pandemic SARS-CoV-2 antigens in lung tissue
topic Medicina
19
lung
COVID
viral
antigens
url https://www.redalyc.org/articulo.oa?id=84373566002
https://www.redalyc.org/journal/843/84373566002/
https://www.redalyc.org/journal/843/84373566002/html/
https://www.redalyc.org/journal/843/84373566002/84373566002.epub
https://www.redalyc.org/journal/843/84373566002/movil