Potentially inappropriate medication on communitydwelling older adults: Longitudinal analysis using the International Mobility in Aging Study
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| Natura: | Artículo científico |
| Lingua: | en |
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Instituto Nacional de Salud
2024
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| author | Édison Pineda |
| author_facet | Édison Pineda |
| contents | Potentially inappropriate medication on communitydwelling older adults: Longitudinal analysis using the International Mobility in Aging Study Édison Pineda Alejandra Fernández Carmen Lucía Curcio Juliana Fernandes de Souza Afshin Vafaei José Fernando Gómez Medicina aged prevalence polypharmacy independent living longitudinal studies Introduction. Medications are a fundamental part of the treatment of multiple pathologies. However, despite their benefits, some are considered potentially inappropriate medications for older people given their safety profile. Epidemiological data differences related to potentially inappropriate medications make it difficult to determine their effects on elderly people.Objective. To estimate the prevalence and types of potentially inappropriate medications using the 2019 Beers Criteria® in a cohort of adults older than 65 years.Materials and methods. We performed an observational, multicenter, retrospective, longitudinal study of a four-year follow-up of potentially inappropriate medications in community-dwelling older adults.Results. We followed 820 participants from five cities for four years (2012-2016) and evaluated them in three different moments (m1 = 2012, m2 = 2014, and m3= 2016). The average age was 69.07 years, and 50.9% were women. The potentially inappropriate medication prevalence in the participants was 40.24%. The potentially inappropriate medications’ mean among the studied subjects in the first moment was 1.65 (SD = 0.963), in the second was 1.73 (SD = 1.032), and in the third was 1.62 (SD = 0.915). There were no statistical differences between measurements (Friedman test, value = 0.204). The most frequent potentially inappropriate medications categories were gastrointestinal (39.4%), analgesics (18.8%), delirium-related drugs (15.4%), benzodiazepines (15.2%), and cardiovascular (14.2%).Conclusions. About half of the population of the community-dwelling older adults had prescriptions of potentially inappropriate medications in a sustained manner and without significant variability over time. Mainly potentially inappropriate medications were gastrointestinal and cardiovascular drugs, analgesics, delirium-related drugs, and benzodiazepines. 2024 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84378930008 https://www.redalyc.org/journal/843/84378930008/ https://www.redalyc.org/journal/843/84378930008/html/ https://www.redalyc.org/journal/843/84378930008/84378930008.epub https://www.redalyc.org/journal/843/84378930008/movil 10.7705/biomedica.6992 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.2 Vol.44 |
| format | Artículo científico |
| id | redalyc_84378930008 |
| institution | Redalyc |
| language | en |
| publishDate | 2024 |
| publisher | Instituto Nacional de Salud |
| spellingShingle | Potentially inappropriate medication on communitydwelling older adults: Longitudinal analysis using the International Mobility in Aging Study Édison Pineda Medicina aged prevalence polypharmacy independent living longitudinal studies Potentially inappropriate medication on communitydwelling older adults: Longitudinal analysis using the International Mobility in Aging Study Édison Pineda Alejandra Fernández Carmen Lucía Curcio Juliana Fernandes de Souza Afshin Vafaei José Fernando Gómez Medicina aged prevalence polypharmacy independent living longitudinal studies Introduction. Medications are a fundamental part of the treatment of multiple pathologies. However, despite their benefits, some are considered potentially inappropriate medications for older people given their safety profile. Epidemiological data differences related to potentially inappropriate medications make it difficult to determine their effects on elderly people.Objective. To estimate the prevalence and types of potentially inappropriate medications using the 2019 Beers Criteria® in a cohort of adults older than 65 years.Materials and methods. We performed an observational, multicenter, retrospective, longitudinal study of a four-year follow-up of potentially inappropriate medications in community-dwelling older adults.Results. We followed 820 participants from five cities for four years (2012-2016) and evaluated them in three different moments (m1 = 2012, m2 = 2014, and m3= 2016). The average age was 69.07 years, and 50.9% were women. The potentially inappropriate medication prevalence in the participants was 40.24%. The potentially inappropriate medications’ mean among the studied subjects in the first moment was 1.65 (SD = 0.963), in the second was 1.73 (SD = 1.032), and in the third was 1.62 (SD = 0.915). There were no statistical differences between measurements (Friedman test, value = 0.204). The most frequent potentially inappropriate medications categories were gastrointestinal (39.4%), analgesics (18.8%), delirium-related drugs (15.4%), benzodiazepines (15.2%), and cardiovascular (14.2%).Conclusions. About half of the population of the community-dwelling older adults had prescriptions of potentially inappropriate medications in a sustained manner and without significant variability over time. Mainly potentially inappropriate medications were gastrointestinal and cardiovascular drugs, analgesics, delirium-related drugs, and benzodiazepines. 2024 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84378930008 https://www.redalyc.org/journal/843/84378930008/ https://www.redalyc.org/journal/843/84378930008/html/ https://www.redalyc.org/journal/843/84378930008/84378930008.epub https://www.redalyc.org/journal/843/84378930008/movil 10.7705/biomedica.6992 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.2 Vol.44 |
| title | Potentially inappropriate medication on communitydwelling older adults: Longitudinal analysis using the International Mobility in Aging Study |
| topic | Medicina aged prevalence polypharmacy independent living longitudinal studies |
| url | https://www.redalyc.org/articulo.oa?id=84378930008 https://www.redalyc.org/journal/843/84378930008/ https://www.redalyc.org/journal/843/84378930008/html/ https://www.redalyc.org/journal/843/84378930008/84378930008.epub https://www.redalyc.org/journal/843/84378930008/movil |