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| Format: | Artículo científico |
| Language: | en |
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Instituto Nacional de Salud
2024
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| Online Access: | https://www.redalyc.org/articulo.oa?id=84379006007 https://www.redalyc.org/journal/843/84379006007/ https://www.redalyc.org/journal/843/84379006007/html/ https://www.redalyc.org/journal/843/84379006007/84379006007.epub https://www.redalyc.org/journal/843/84379006007/movil |
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Table of Contents:
- Circulating zinc levels and cardiometabolic risk-related variables in adults Milton Fabián Suárez-Ortegón Alejandra Arbeláez José Guillermo Ortega-Ávila Mildrey Mosquera Medicina Zinc triglycerides micronutrients heart disease risk factors Introduction Altered serum zinc levels, lower and higher than values in healthy controls, have been observed in individuals affected by non-communicable chronic diseases. However, to date, studies describing potential determinants of zinc levels in general populations free of chronic diseases appear to be limited.Objective To evaluate whether nutrient intake, biochemical and clinical measures, lifestyle, and family history of cardio-metabolic diseases are independently associated with zinc levels in apparently healthy individuals.Materials and methods We evaluated 239 healthy subjects. Serum zinc was measured via flame atomic absorption spectrometry, and the remaining biochemical markers were assessed using enzymatic colorimetric methods. Standard techniques were employed to quantify waist circumference, height, and weight. Body fat was measured via bioimpedance, and blood pressure was measured using digital sphygmomanometers. We applied a survey to record the personal and family history of non-communicable chronic diseases, and nutrient intake was estimated using the 24-hour recall method.Results Women had lower serum zinc levels than men. In multivariate analyzes, total fat intake (β = -0.15; standard error = 0.03; p < 0.001), plasma log-triglycerides (β = -10.18; standard error = 3.9; p = 0.010), and female gender (β = -6.81; standard error = 3.3; p = 0.043) were significant predictors for serum zinc levels. Zinc intake was not significantly related to serum zinc in univariate and multivariate analyses.Conclusions Variables related to cardiometabolic risk, such as plasma triglyceride levels and total fat intake, were associated with serum zinc levels in individuals without a diagnosis of chronic or infectious/inflammatory diseases. Further studies are required to confirm our findings and to evaluate possible biological mechanisms for these relationships. 2024 artículo científico 0120-4157 https://www.redalyc.org/articulo.oa?id=84379006007 https://www.redalyc.org/journal/843/84379006007/ https://www.redalyc.org/journal/843/84379006007/html/ https://www.redalyc.org/journal/843/84379006007/84379006007.epub https://www.redalyc.org/journal/843/84379006007/movil 10.7705/biomedica.6882 en http://www.redalyc.org/revista.oa?id=843 Biomédica application/pdf Instituto Nacional de Salud Biomédica (Colombia) Num.1 Vol.44