Toxicity of volatile compounds of Senecio grisebachii BAKER (margarita) Flowers, in mice
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| Format: | Artículo científico |
| Langue: | en |
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Instituto Nacional de Tecnología Agropecuaria
2003
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| _version_ | 1876475406488436736 |
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| author | A. Romero |
| author_facet | A. Romero |
| contents | Toxicity of volatile compounds of Senecio grisebachii BAKER (margarita) Flowers, in mice A. Romero E. M. Ciotti P. Zeinsteger P. Teibler M. Montenegro E. Rios O. Acosta De Perez N. Jorge Agrociencias liver terpenes intestine Senecio grisebachii Intoxication caused by Senecio spp is characterized by an irreversibledamage of the liver cells due to the action of pyrrolizidine alkaloidspresent in these plants. They contain other groups of volatile components,such as terpenes, which may also be toxic.An aqueous extract obtained by water steam distillation of Seneciogrisebach ii fresh flowers was orally given to mice (0.5 mL/mouse/day)for 30 days. Animals were observed periodically. Weight loss, pale mucousmembrane color, low body temperature and decreased capillary refill timewere symptoms compatible with dehydration.Histopathological findings showed congestion and edema in smalland large intestines. Liver showed hydropic and fatty degeneration withcentrilobular necrosis. Results indicate that terpenes alter membranepermeability regulation processes on the epitheliums of the digestive system 2003 artículo científico 0325-8718 https://www.redalyc.org/articulo.oa?id=86432209 en http://www.redalyc.org/revista.oa?id=864 RIA. Revista de Investigaciones Agropecuarias application/pdf Instituto Nacional de Tecnología Agropecuaria RIA. Revista de Investigaciones Agropecuarias (Argentina) Num.2 Vol.32 |
| format | Artículo científico |
| id | redalyc_86432209 |
| institution | Redalyc |
| language | en |
| publishDate | 2003 |
| publisher | Instituto Nacional de Tecnología Agropecuaria |
| spellingShingle | Toxicity of volatile compounds of Senecio grisebachii BAKER (margarita) Flowers, in mice A. Romero Agrociencias liver terpenes intestine Senecio grisebachii Toxicity of volatile compounds of Senecio grisebachii BAKER (margarita) Flowers, in mice A. Romero E. M. Ciotti P. Zeinsteger P. Teibler M. Montenegro E. Rios O. Acosta De Perez N. Jorge Agrociencias liver terpenes intestine Senecio grisebachii Intoxication caused by Senecio spp is characterized by an irreversibledamage of the liver cells due to the action of pyrrolizidine alkaloidspresent in these plants. They contain other groups of volatile components,such as terpenes, which may also be toxic.An aqueous extract obtained by water steam distillation of Seneciogrisebach ii fresh flowers was orally given to mice (0.5 mL/mouse/day)for 30 days. Animals were observed periodically. Weight loss, pale mucousmembrane color, low body temperature and decreased capillary refill timewere symptoms compatible with dehydration.Histopathological findings showed congestion and edema in smalland large intestines. Liver showed hydropic and fatty degeneration withcentrilobular necrosis. Results indicate that terpenes alter membranepermeability regulation processes on the epitheliums of the digestive system 2003 artículo científico 0325-8718 https://www.redalyc.org/articulo.oa?id=86432209 en http://www.redalyc.org/revista.oa?id=864 RIA. Revista de Investigaciones Agropecuarias application/pdf Instituto Nacional de Tecnología Agropecuaria RIA. Revista de Investigaciones Agropecuarias (Argentina) Num.2 Vol.32 |
| title | Toxicity of volatile compounds of Senecio grisebachii BAKER (margarita) Flowers, in mice |
| topic | Agrociencias liver terpenes intestine Senecio grisebachii |
| url | https://www.redalyc.org/articulo.oa?id=86432209 |