Novel type 4 secretion system (T4SS)-related genes of Edwardsiella tarda

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Autor principal: Noel Verjan-García
Formato: Artículo científico
Lenguaje:en
Publicado: Universidad de Los Llanos 2015
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author Noel Verjan-García
author_facet Noel Verjan-García
contents Novel type 4 secretion system (T4SS)-related genes of Edwardsiella tarda Noel Verjan-García Carlos A. Iregui Ikuo Hirono Veterinaria Virulence T4SS genes Pathogenesis Edwardsiella tarda is a Gram-negative bacterium that causes edwardsiellosis, a disease of fish and mammals including humans and characterized by multiple abscesses. Different strains of E. tarda possess a number of virulence, antibiotic- resistance, and toxin secretion system-related genes that explain in some extent its capacity to survive within phagocytic cells and to infect a variety of hosts. Previously we introduced a virulent E. tarda strain (ETSJ54) isolated from Japanese flounder ( Paralichthys olivaceus ) with edwardsiellosis and reported a number of virulence-related genes. In this study we have re-analyzed the sequencing data of ETSJ54 and identified novel type IV secretion system-related genes, most of them were flanked by transposase and plasmid encoding genes. Interestingly, their nucleotide sequence had no identity to those of the genes published in the E. tarda EIB202 genome, a virulent strain isolated from turbot ( Scophthalmus maximus ) in China. The results suggest differences in gene content between geographically distinct E. tarda strains that may encourage additional E. tarda genome sequencing projects. 2015 artículo científico 0121-3709 https://www.redalyc.org/articulo.oa?id=89645829005 en http://www.redalyc.org/revista.oa?id=896 Orinoquia application/pdf Universidad de Los Llanos Orinoquia (Colombia) Num.2 Vol.19
format Artículo científico
id redalyc_89645829005
institution Redalyc
language en
publishDate 2015
publisher Universidad de Los Llanos
spellingShingle Novel type 4 secretion system (T4SS)-related genes of Edwardsiella tarda
Noel Verjan-García
Veterinaria
Virulence
T4SS genes
Pathogenesis
Novel type 4 secretion system (T4SS)-related genes of Edwardsiella tarda Noel Verjan-García Carlos A. Iregui Ikuo Hirono Veterinaria Virulence T4SS genes Pathogenesis Edwardsiella tarda is a Gram-negative bacterium that causes edwardsiellosis, a disease of fish and mammals including humans and characterized by multiple abscesses. Different strains of E. tarda possess a number of virulence, antibiotic- resistance, and toxin secretion system-related genes that explain in some extent its capacity to survive within phagocytic cells and to infect a variety of hosts. Previously we introduced a virulent E. tarda strain (ETSJ54) isolated from Japanese flounder ( Paralichthys olivaceus ) with edwardsiellosis and reported a number of virulence-related genes. In this study we have re-analyzed the sequencing data of ETSJ54 and identified novel type IV secretion system-related genes, most of them were flanked by transposase and plasmid encoding genes. Interestingly, their nucleotide sequence had no identity to those of the genes published in the E. tarda EIB202 genome, a virulent strain isolated from turbot ( Scophthalmus maximus ) in China. The results suggest differences in gene content between geographically distinct E. tarda strains that may encourage additional E. tarda genome sequencing projects. 2015 artículo científico 0121-3709 https://www.redalyc.org/articulo.oa?id=89645829005 en http://www.redalyc.org/revista.oa?id=896 Orinoquia application/pdf Universidad de Los Llanos Orinoquia (Colombia) Num.2 Vol.19
title Novel type 4 secretion system (T4SS)-related genes of Edwardsiella tarda
topic Veterinaria
Virulence
T4SS genes
Pathogenesis
url https://www.redalyc.org/articulo.oa?id=89645829005