Zona pellucida: An extracellular matrix with applications in the study of immunocontraception in domestic carnivores
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidad del Zulia
2004
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| _version_ | 1876450067821363200 |
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| author | Alfonso Sánchez Riquelme |
| author_facet | Alfonso Sánchez Riquelme |
| contents | Zona pellucida: An extracellular matrix with applications in the study of immunocontraception in domestic carnivores Alfonso Sánchez Riquelme Mónica De los Reyes Solovera Veterinaria feline canine vaccines Zona pellucida anticonception Zona pellucida (ZP) is an extracellular matrix surrounding themammalian oocyte. In most mammalian species this matrixconsists of three families of glycoproteins likely to sufferseveral postraductional modifications to acquire differentimmunological and biochemical properties. The ZP areinvolved in the initial recognition and binding events of spermto oocyte investments. Because of its major role in thefertilization process (interaction with sperm, induction ofacrosome reaction, control of polyspermy) the ZP has beenused as an antigen to induce immunological response in orderto produce female infertility, a relevant issue in domesticcarnivores. Depending on the predominant immunologicalresponse (humoral or cellular) the infertility can be reversible(Immunocontraception) or irreversible (immunosterilization),respectively. Currently the goal is to develop recombinant ZPantigen with immunodominant epitopes in order to producepredictable and safely response 2004 artículo científico 0798-2259 https://www.redalyc.org/articulo.oa?id=95914510 en http://www.redalyc.org/revista.oa?id=959 Revista Científica application/pdf Universidad del Zulia Revista Científica (República Bolivariana de Venezuela) Num.5 Vol.XIV |
| format | Artículo científico |
| id | redalyc_95914510 |
| institution | Redalyc |
| language | en |
| publishDate | 2004 |
| publisher | Universidad del Zulia |
| spellingShingle | Zona pellucida: An extracellular matrix with applications in the study of immunocontraception in domestic carnivores Alfonso Sánchez Riquelme Veterinaria feline canine vaccines Zona pellucida anticonception Zona pellucida: An extracellular matrix with applications in the study of immunocontraception in domestic carnivores Alfonso Sánchez Riquelme Mónica De los Reyes Solovera Veterinaria feline canine vaccines Zona pellucida anticonception Zona pellucida (ZP) is an extracellular matrix surrounding themammalian oocyte. In most mammalian species this matrixconsists of three families of glycoproteins likely to sufferseveral postraductional modifications to acquire differentimmunological and biochemical properties. The ZP areinvolved in the initial recognition and binding events of spermto oocyte investments. Because of its major role in thefertilization process (interaction with sperm, induction ofacrosome reaction, control of polyspermy) the ZP has beenused as an antigen to induce immunological response in orderto produce female infertility, a relevant issue in domesticcarnivores. Depending on the predominant immunologicalresponse (humoral or cellular) the infertility can be reversible(Immunocontraception) or irreversible (immunosterilization),respectively. Currently the goal is to develop recombinant ZPantigen with immunodominant epitopes in order to producepredictable and safely response 2004 artículo científico 0798-2259 https://www.redalyc.org/articulo.oa?id=95914510 en http://www.redalyc.org/revista.oa?id=959 Revista Científica application/pdf Universidad del Zulia Revista Científica (República Bolivariana de Venezuela) Num.5 Vol.XIV |
| title | Zona pellucida: An extracellular matrix with applications in the study of immunocontraception in domestic carnivores |
| topic | Veterinaria feline canine vaccines Zona pellucida anticonception |
| url | https://www.redalyc.org/articulo.oa?id=95914510 |