Theoretical basis for the study of the effect of base composition on DNA melting
Fuente:
Universidad Nacional Autónoma de México
Resumen: We extend the ideas used to describe the glass transition in strong glasses employing the stochastic matrix method, giving a theoretical framework for the study of the configurational changes and the melting temperature of DNA. Our theoretical model enables a systematic study of the melting...
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| Autori principali: | , |
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| Natura: | Artículo de Investigación |
| Lingua: | inglese |
| Pubblicazione: |
Sociedad Mexicana de Física, A.C.
2004
Universidad Nacional Autónoma de México; Facultad de Ciencias |
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| _version_ | 1877697768769716225 |
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| author | Dagdug, L. Young, L. |
| author_facet | Dagdug, L. Young, L. |
| author_sort | Dagdug, L. |
| collection | Repositorio Institucional UNAM |
| description | Resumen: We extend the ideas used to describe the glass transition in strong glasses employing the stochastic matrix method, giving a theoretical framework for the study of the configurational changes and the melting temperature of DNA. Our theoretical model enables a systematic study of the melting transition and the melting temperature dependence on the sequence differences in vertical stacking. Taking into account the fractional composition in a single strand, exact analytic results are given for the fraction of bonds intact and denatured at a particular temperature. This method is applicable to long DNA as well as RNA. |
| format | Artículo de Investigación |
| id | unam-40798 |
| institution | Universidad Nacional Autónoma de México |
| language | English |
| publishDate | 2004 |
| publisher | Sociedad Mexicana de Física, A.C. Universidad Nacional Autónoma de México; Facultad de Ciencias |
| record_format | dspace |
| spelling | Theoretical basis for the study of the effect of base composition on DNA melting Dagdug, L. Young, L. Físico Matemáticas y Ciencias de la Tierra DNA melting temperature stochastic matrix method Procedencia: Universidad Nacional Autónoma de México Repositorio Institucional de la UNAM: https://repositorio.unam.mx/ Resumen: We extend the ideas used to describe the glass transition in strong glasses employing the stochastic matrix method, giving a theoretical framework for the study of the configurational changes and the melting temperature of DNA. Our theoretical model enables a systematic study of the melting transition and the melting temperature dependence on the sequence differences in vertical stacking. Taking into account the fractional composition in a single strand, exact analytic results are given for the fraction of bonds intact and denatured at a particular temperature. This method is applicable to long DNA as well as RNA. Sociedad Mexicana de Física, A.C. Universidad Nacional Autónoma de México; Facultad de Ciencias 2004-01-01 Text Artículo de Investigación application/pdf Cita bibliográfica: Dagdug, L., et al. (2004). Theoretical basis for the study of the effect of base composition on DNA melting. Revista Mexicana de Física; Vol 50, No 6: 594-0. Recuperado de https://rmf.smf.mx/ojs/rmf/article/view/3320 ISSN: 2683-2224 (digital); 0035-001X (impresa) https://repositorio.unam.mx/contenidos/40798 eng Revista Mexicana de Física; Vol 50, No 6 (2004): 594-0 https://rmf.smf.mx/ojs/rmf/index Nivel de acceso: Público La titularidad de los derechos patrimoniales de esta obra pertenece a las instituciones editoras. Su uso se rige por una licencia Creative Commons BY-NC-ND 4.0 Internacional, https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.es, fecha de asignación de la licencia 2004-01-01, para un uso diferente consultar al responsable jurídico del repositorio por medio de rmf@ciencias.unam.mx |
| spellingShingle | Theoretical basis for the study of the effect of base composition on DNA melting Dagdug, L. Young, L. Físico Matemáticas y Ciencias de la Tierra DNA melting temperature stochastic matrix method |
| title | Theoretical basis for the study of the effect of base composition on DNA melting |
| title_full | Theoretical basis for the study of the effect of base composition on DNA melting |
| title_fullStr | Theoretical basis for the study of the effect of base composition on DNA melting |
| title_full_unstemmed | Theoretical basis for the study of the effect of base composition on DNA melting |
| title_short | Theoretical basis for the study of the effect of base composition on DNA melting |
| title_sort | theoretical basis for the study of the effect of base composition on dna melting |
| topic | Físico Matemáticas y Ciencias de la Tierra DNA melting temperature stochastic matrix method |
| topic_facet | Físico Matemáticas y Ciencias de la Tierra DNA melting temperature stochastic matrix method |
| url | https://repositorio.unam.mx/contenidos/40798 |