Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2026
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Reply to Letter: “Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring” by Saccà and Pelto Regarding “Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab”
by: Lea Gerischer, et al.
Published: (2026)
by: Lea Gerischer, et al.
Published: (2026)
Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy
by: Julie Choi, et al.
Published: (2025)
by: Julie Choi, et al.
Published: (2025)
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
by: Lea Gerischer, et al.
Published: (2025)
by: Lea Gerischer, et al.
Published: (2025)
Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy
by: Jiahui Mai, et al.
Published: (2024)
by: Jiahui Mai, et al.
Published: (2024)
Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy
by: Daniel Weintraub, et al.
Published: (2026)
by: Daniel Weintraub, et al.
Published: (2026)
Age‐Related Characteristics of SYT1 ‐Associated Neurodevelopmental Disorder
by: Sam G. Norwitz, et al.
Published: (2025)
by: Sam G. Norwitz, et al.
Published: (2025)
The Diagnostic Value of Visual Evoked Potentials in Chronic Disorders of Consciousness
by: Letizia Clementi, et al.
Published: (2025)
by: Letizia Clementi, et al.
Published: (2025)
Prominent Movement Disorders in RNU2 ‐2‐Related Spliceosomopathy
by: Magdalena Krygier, et al.
Published: (2026)
by: Magdalena Krygier, et al.
Published: (2026)
Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review
by: Zhuoran Wang, et al.
Published: (2025)
by: Zhuoran Wang, et al.
Published: (2025)
CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals
by: Juan P. Vazquez, et al.
Published: (2025)
by: Juan P. Vazquez, et al.
Published: (2025)
Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability
by: Jean Paul Medina Carrion, et al.
Published: (2025)
by: Jean Paul Medina Carrion, et al.
Published: (2025)
Bilateral versus Unilateral Training With Rhythmic Auditory Cueing in Stroke Rehabilitation: Effects on Upper Limb Function and Interhemispheric Inhibition
by: Fangfang Qian, et al.
Published: (2025)
by: Fangfang Qian, et al.
Published: (2025)
Vestibular Patient Journey: Insights From Vestibular Disorders Association ( VeDA ) Registry
by: Ali Rafati, et al.
Published: (2026)
by: Ali Rafati, et al.
Published: (2026)
Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period
by: Chloë A. Kerridge, et al.
Published: (2025)
by: Chloë A. Kerridge, et al.
Published: (2025)
Long COVID in People With Multiple Sclerosis and Related Disorders: A Multicenter Cross‐Sectional Study
by: Chen Hu, et al.
Published: (2025)
by: Chen Hu, et al.
Published: (2025)
Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder
by: Jonathan D. Santoro, et al.
Published: (2025)
by: Jonathan D. Santoro, et al.
Published: (2025)
Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial
by: Chuan Xu, et al.
Published: (2026)
by: Chuan Xu, et al.
Published: (2026)
Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering
by: Bade Gulec, et al.
Published: (2026)
by: Bade Gulec, et al.
Published: (2026)
Exploring if Longitudinal Changes on PET Imaging Can Serve as a Biomarker for Stiff Person Syndrome Spectrum Disorders
by: Munther M. Queisi, et al.
Published: (2025)
by: Munther M. Queisi, et al.
Published: (2025)
Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI ‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response
by: Maximilian Einsiedler, et al.
Published: (2025)
by: Maximilian Einsiedler, et al.
Published: (2025)
High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study
by: Xiang Li, et al.
Published: (2025)
by: Xiang Li, et al.
Published: (2025)
Baseline systolic blood pressure, hypertension history, and efficacy of remote ischemic conditioning
by: Ji‐Ru Cai, et al.
Published: (2024)
by: Ji‐Ru Cai, et al.
Published: (2024)
Decreased Serum 5‐ HT : Clinical Correlates and Regulatory Role in NMJ of MG
by: Xinru Shen, et al.
Published: (2025)
by: Xinru Shen, et al.
Published: (2025)
Management and Outcomes in Confirmed or Suspected Acute Symptomatic Seizure: Role of Structured Outpatient Care
by: Vineet Punia, et al.
Published: (2025)
by: Vineet Punia, et al.
Published: (2025)
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
by: Roman Schniepp, et al.
Published: (2026)
by: Roman Schniepp, et al.
Published: (2026)
Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis
by: Katalin Lugosi, et al.
Published: (2025)
by: Katalin Lugosi, et al.
Published: (2025)
Patient Selection in Deep Brain Stimulation: A Role for Transcranial Direct Current Stimulation to Enhance the Levodopa Challenge?
by: Lukas L. Goede, et al.
Published: (2025)
by: Lukas L. Goede, et al.
Published: (2025)
Infantile Krabbe disease (0–12 months), progression, and recommended endpoints for clinical trials
by: Melissa R. Greco, et al.
Published: (2024)
by: Melissa R. Greco, et al.
Published: (2024)
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT / GPX4 ‐Regulated Ferroptosis
by: Peng Tao, et al.
Published: (2025)
by: Peng Tao, et al.
Published: (2025)
Remaining Burden of Spinal Muscular Atrophy Among Treated Patients: A Survey of Patients and Caregivers
by: Julie A. Parsons, et al.
Published: (2025)
by: Julie A. Parsons, et al.
Published: (2025)
Comparison of intraepidermal nerve fiber density and confocal corneal microscopy for neuropathy
by: Evan L. Reynolds, et al.
Published: (2024)
by: Evan L. Reynolds, et al.
Published: (2024)
Expert panel curation of 31 genes in relation to limb girdle muscular dystrophy
by: Shruthi Mohan, et al.
Published: (2024)
by: Shruthi Mohan, et al.
Published: (2024)
Association of multiple trace metals in scalp hair with glioma risk: the mediating role of inflammation
by: Lingjun Yan, et al.
Published: (2024)
by: Lingjun Yan, et al.
Published: (2024)
ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria
by: Hee‐Jae Jung, et al.
Published: (2025)
by: Hee‐Jae Jung, et al.
Published: (2025)
Clinical Trial Readiness in Limb Girdle Muscular Dystrophy R1 (LGMDR1): A GRASP Consortium Study
by: Stephanie M. Hunn, et al.
Published: (2025)
by: Stephanie M. Hunn, et al.
Published: (2025)
RNA mis‐splicing in children with congenital myotonic dystrophy is associated with physical function
by: Julia M. Hartman, et al.
Published: (2024)
by: Julia M. Hartman, et al.
Published: (2024)
Investigating ITM2B‐associated ataxia in a Taiwanese cerebellar ataxia cohort
by: Shih‐Yu Fang, et al.
Published: (2024)
by: Shih‐Yu Fang, et al.
Published: (2024)
Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1
by: Lindsay N. Alfano, et al.
Published: (2025)
by: Lindsay N. Alfano, et al.
Published: (2025)
Association of CDKN2A /B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma
by: Jiawei Cai, et al.
Published: (2026)
by: Jiawei Cai, et al.
Published: (2026)
Progressive myoclonic ataxia as an initial symptom of typical type I sialidosis with NEU1 mutation
by: Jingjing Lin, et al.
Published: (2024)
by: Jingjing Lin, et al.
Published: (2024)
Similar Items
-
Reply to Letter: “Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring” by Saccà and Pelto Regarding “Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab”
by: Lea Gerischer, et al.
Published: (2026) -
Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy
by: Julie Choi, et al.
Published: (2025) -
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
by: Lea Gerischer, et al.
Published: (2025) -
Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy
by: Jiahui Mai, et al.
Published: (2024) -
Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy
by: Daniel Weintraub, et al.
Published: (2026)