Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Yungeng Wei, Hua Guo, Xiangsheng Yang, Xiao Xiao Tang |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2026
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis
by: Tao Yang, et al.
Published: (2026)
by: Tao Yang, et al.
Published: (2026)
Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis
by: Jiayu Guo, et al.
Published: (2025)
by: Jiayu Guo, et al.
Published: (2025)
NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring (Adv. Sci. 11/2026)
by: Xiwen Dong, et al.
Published: (2026)
by: Xiwen Dong, et al.
Published: (2026)
Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis
by: Yu Cao, et al.
Published: (2025)
by: Yu Cao, et al.
Published: (2025)
GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation
by: Da Mi Kim, et al.
Published: (2025)
by: Da Mi Kim, et al.
Published: (2025)
PLIN2 Promotes Lipid Accumulation in Ascites‐Associated Macrophages and Ovarian Cancer Progression by HIF1α/SPP1 Signaling
by: Hui Luo, et al.
Published: (2025)
by: Hui Luo, et al.
Published: (2025)
Succinic Acid‐Induced Macrophage Endocytosis Promotes Extracellular Vesicle‐Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis‐Associated Pulmonary Fibrosis
by: Wenyu Yang, et al.
Published: (2025)
by: Wenyu Yang, et al.
Published: (2025)
Macrophages Transdifferentiate Into Myofibroblasts During Ocular Surface Inflammation
by: Nishant R. Sinha, et al.
Published: (2025)
by: Nishant R. Sinha, et al.
Published: (2025)
IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma
by: Zhaoxuan Wang, et al.
Published: (2025)
by: Zhaoxuan Wang, et al.
Published: (2025)
Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling
by: Yibing Chen, et al.
Published: (2025)
by: Yibing Chen, et al.
Published: (2025)
Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation
by: Liqun Wang, et al.
Published: (2026)
by: Liqun Wang, et al.
Published: (2026)
Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non‐Small‐Cell Lung Carcinoma (Adv. Sci. 1/2024)
by: Philip Chiu‐Tsun Tang, et al.
Published: (2024)
by: Philip Chiu‐Tsun Tang, et al.
Published: (2024)
Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2 + PIRB + Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis
by: Shuqi Wei, et al.
Published: (2025)
by: Shuqi Wei, et al.
Published: (2025)
Pulmonary‐Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy
by: Xue‐Na Li, et al.
Published: (2025)
by: Xue‐Na Li, et al.
Published: (2025)
Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages
by: Zhendong Zhu, et al.
Published: (2026)
by: Zhendong Zhu, et al.
Published: (2026)
Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1 + Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid
by: Hongyu Wang, et al.
Published: (2025)
by: Hongyu Wang, et al.
Published: (2025)
Engineered MSCs Break Endothelial‐Myofibroblast Crosstalk in Pulmonary Fibrosis: Reconstructing the Vascular Niche
by: Yue‐Fei Fang, et al.
Published: (2025)
by: Yue‐Fei Fang, et al.
Published: (2025)
METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis
by: Tao Huang, et al.
Published: (2025)
by: Tao Huang, et al.
Published: (2025)
RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC + Tumor‐Associated Macrophages
by: Yinheng Luo, et al.
Published: (2025)
by: Yinheng Luo, et al.
Published: (2025)
Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis
by: Li Lu, et al.
Published: (2025)
by: Li Lu, et al.
Published: (2025)
Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling
by: Xiaolan Zheng, et al.
Published: (2026)
by: Xiaolan Zheng, et al.
Published: (2026)
Liver Kinase B1 in CD11c + Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling
by: Wenqing Zhang, et al.
Published: (2026)
by: Wenqing Zhang, et al.
Published: (2026)
Single‐Cell Spatial Transcriptomics Unveils Platelet‐Fueled Cycling Macrophages for Kidney Fibrosis
by: Jun Liu, et al.
Published: (2024)
by: Jun Liu, et al.
Published: (2024)
Targeting Nuclear Receptor Coactivator SRC‐1 Prevents Colorectal Cancer Immune Escape by Reducing Transcription and Protein Stability of PD‐L1
by: Yilin Hong, et al.
Published: (2024)
by: Yilin Hong, et al.
Published: (2024)
SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury
by: Feng Zhang, et al.
Published: (2026)
by: Feng Zhang, et al.
Published: (2026)
ShK‐modified UCMSCs Inhibit M1‐Like Macrophage Polarization and Alleviate Osteoarthritis Progression via PI3K/Akt Axis
by: Wenshu Wu, et al.
Published: (2024)
by: Wenshu Wu, et al.
Published: (2024)
The Spermine Oxidase/Spermine Axis Coordinates ATG5‐Mediated Autophagy to Orchestrate Renal Senescence and Fibrosis
by: Dan Luo, et al.
Published: (2024)
by: Dan Luo, et al.
Published: (2024)
Supramolecular Nanofibers Ameliorate Bleomycin‐Induced Pulmonary Fibrosis by Restoring Autophagy
by: Debin Zheng, et al.
Published: (2024)
by: Debin Zheng, et al.
Published: (2024)
Hypertensive Pressure Mechanosensing Alone Triggers Lipid Droplet Accumulation and Transdifferentiation of Vascular Smooth Muscle Cells to Foam Cells (Adv. Sci. 9/2024)
by: Pamela Swiatlowska, et al.
Published: (2024)
by: Pamela Swiatlowska, et al.
Published: (2024)
Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections
by: Zhaoheng Lin, et al.
Published: (2025)
by: Zhaoheng Lin, et al.
Published: (2025)
MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis
by: Peng Chen, et al.
Published: (2026)
by: Peng Chen, et al.
Published: (2026)
Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis
by: Menglan Wang, et al.
Published: (2026)
by: Menglan Wang, et al.
Published: (2026)
Sympathetic Activation Promotes Kidney Fibrosis in Mice via Macrophage‐Derived N2ICD‐Enriched Extracellular Vesicles
by: Huiwen Ren, et al.
Published: (2025)
by: Huiwen Ren, et al.
Published: (2025)
CD169+ Macrophages Mediate the Immune Response of Allergic Rhinitis Through the Keap1/Nrf2/HO‐1 Axis
by: Wenwen Qi, et al.
Published: (2024)
by: Wenwen Qi, et al.
Published: (2024)
A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis
by: Wei Wang, et al.
Published: (2025)
by: Wei Wang, et al.
Published: (2025)
Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis
by: Muhai Deng, et al.
Published: (2026)
by: Muhai Deng, et al.
Published: (2026)
Targeted Inhibition of CD74 + Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression
by: Rui Peng, et al.
Published: (2025)
by: Rui Peng, et al.
Published: (2025)
Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis
by: Rui Hua, et al.
Published: (2025)
by: Rui Hua, et al.
Published: (2025)
Aberrant Chitinase 3‐Like 1 Expression in Basal Cells Contributes to Systemic Sclerosis Fibrosis
by: Xiuyuan Wang, et al.
Published: (2024)
by: Xiuyuan Wang, et al.
Published: (2024)
CD147‐K148me2‐Driven Tumor Cell‐Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis
by: Ke Wang, et al.
Published: (2024)
by: Ke Wang, et al.
Published: (2024)
Similar Items
-
RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis
by: Tao Yang, et al.
Published: (2026) -
Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis
by: Jiayu Guo, et al.
Published: (2025) -
NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring (Adv. Sci. 11/2026)
by: Xiwen Dong, et al.
Published: (2026) -
Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis
by: Yu Cao, et al.
Published: (2025) -
GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation
by: Da Mi Kim, et al.
Published: (2025)