Synergistic Remodeling of Tumor Immune Microenvironment via a DNA Nanodevice Integrating STING Activation and Lysosome‐Targeted PD‐L1 Degradation
Fuente:
Wiley Open Access
Saved in:
| Main Authors: | Haoxiang Li, Min Hou, Shasha Sun, Jun Cao, Jian‐Hui Jiang, Jianjun He |
|---|---|
| Format: | Artículo Open Access |
| Published: |
Wiley
2026
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Inhibitory Microenvironment Remodeling Enhances STING Activation for Solid Tumor Immunotherapy
by: Wenming Fang, et al.
Published: (2025)
by: Wenming Fang, et al.
Published: (2025)
Lysosome‐Targeting Bacterial Outer Membrane Vesicles for Tumor Specific Degradation of PD‐L1
by: Panpan Ji, et al.
Published: (2024)
by: Panpan Ji, et al.
Published: (2024)
Mitochondria‐Targeted Nanoadjuvants Induced Multi‐Functional Immune‐Microenvironment Remodeling to Sensitize Tumor Radio‐Immunotherapy
by: Zaigang Zhou, et al.
Published: (2024)
by: Zaigang Zhou, et al.
Published: (2024)
Engineering Bimetallic Polyphenol for Mild Photothermal Osteosarcoma Therapy and Immune Microenvironment Remodeling by Activating Pyroptosis and cGAS‐STING Pathway
by: Kaiyuan Liu, et al.
Published: (2024)
by: Kaiyuan Liu, et al.
Published: (2024)
Engineering a Tumor‐Targeted MgH 2 @Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation
by: Xuyu Gu, et al.
Published: (2026)
by: Xuyu Gu, et al.
Published: (2026)
Modular Engineering of Enzyme‐Activatable DNA Nanodevices for Endoplasmic Reticulum‐Targeted Photodynamic Antitumor Therapy
by: Dejie Lu, et al.
Published: (2025)
by: Dejie Lu, et al.
Published: (2025)
Autophagy‐Targeting Fe–Cu Nanozyme for Tumor Immune Microenvironment Remodeling and Image‐Guided Cancer Immunotherapy
by: Li Yan, et al.
Published: (2025)
by: Li Yan, et al.
Published: (2025)
Nanoparticle‐Mediated Tumor Microenvironment Remodeling Favors the Communication with the Immune Cells for Tumor Killing
by: Elena Lucena‐Sánchez, et al.
Published: (2024)
by: Elena Lucena‐Sánchez, et al.
Published: (2024)
Platinum‐Metformin Conjugates Acting as Promising PD‐L1 Inhibitors through the AMP‐Activated Protein Kinase Mediated Lysosomal Degradation Pathway
by: Bin Liu, et al.
Published: (2024)
by: Bin Liu, et al.
Published: (2024)
Lactate‐Depleting Engineered Probiotics Remodel the Tumor Microenvironment and Enhance PD‐1 Blockade
by: Jing Zhang, et al.
Published: (2026)
by: Jing Zhang, et al.
Published: (2026)
Lysosome Targeted Nanoparticle Aggregation Reverses Immunosuppressive Tumor Microenvironment for Cancer Immunotherapy
by: Yumeng Xing, et al.
Published: (2024)
by: Yumeng Xing, et al.
Published: (2024)
A Highly Tumor‐Permeating DNA Nanoplatform for Efficient Remodeling of Immunosuppressive Tumor Microenvironments
by: Hong Wang, et al.
Published: (2024)
by: Hong Wang, et al.
Published: (2024)
CEACAM1 Is Associated With an Immune‐Activated Tumor Microenvironment and Therapeutic Stratification in Sarcoma
by: Ziqi Cao, et al.
Published: (2026)
by: Ziqi Cao, et al.
Published: (2026)
Golgi Apparatus‐Targeting Immunostimulant for Synergistic Activation of Antitumor Immunity via Pyroptosis Induction and PD‐L1 Degradation
by: Rong‐Rong Zheng, et al.
Published: (2026)
by: Rong‐Rong Zheng, et al.
Published: (2026)
A Bifunctional Lysosome‐Targeting Chimera Nanoplatform for Tumor‐Selective Protein Degradation and Enhanced Cancer Immunotherapy
by: Yumeng Xing, et al.
Published: (2025)
by: Yumeng Xing, et al.
Published: (2025)
DNA‐Loaded Nanoparticles Reprogram the Tumor Immune Microenvironment to Treat Brain Tumors
by: Joanna Yang, et al.
Published: (2026)
by: Joanna Yang, et al.
Published: (2026)
Fibroblast Activation Protein Alpha-Targeted Nanoparticles for Tumor Microenvironment Remodeling and Antitumor Therapy in Triple-Negative Breast Cancer
by: Lameirinhas, A, et al.
Published: (2026)
by: Lameirinhas, A, et al.
Published: (2026)
A Tumor‐Targeted Cascade Catalytic Nanoreactor for Microenvironment Remodeling and Photodynamic Immunotherapy
by: Xiang‐Yu Ma, et al.
Published: (2026)
by: Xiang‐Yu Ma, et al.
Published: (2026)
Cell Membrane‐Targeted J‐Aggregation Strategy for Synergistic Immune Checkpoint Degradation and Immunogenic Pyroptosis to Augment Tumor Immunotherapy
by: Xiaona Xu, et al.
Published: (2025)
by: Xiaona Xu, et al.
Published: (2025)
Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment
by: Zhenghao Wu, et al.
Published: (2025)
by: Zhenghao Wu, et al.
Published: (2025)
Assembled DNA Nanostructure to Precisely Induced cGAS‐STING Activation for Cancer Immunotherapy
by: Li He, et al.
Published: (2026)
by: Li He, et al.
Published: (2026)
A Bioresponsive Hydrogel Remodels the Hypoxic‐Immune Microenvironment via Synergistic Phototherapy for Chronic Wound Regeneration
by: Chenglong Xue, et al.
Published: (2025)
by: Chenglong Xue, et al.
Published: (2025)
NIR Absorbing Organic Chromophores Combination with NSAIDs for Remodeling of the Inflammatory Microenvironment to Amplify Tumor Ferroptosis‐Photothermal Synergistic Therapy
by: Zhian Chen, et al.
Published: (2024)
by: Zhian Chen, et al.
Published: (2024)
A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy
by: Jia‐Yi Lin, et al.
Published: (2025)
by: Jia‐Yi Lin, et al.
Published: (2025)
CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling
by: Kailai Li, et al.
Published: (2025)
by: Kailai Li, et al.
Published: (2025)
A 5‐Fluorouracil‐Constituted DNA Hydrogel Embedded with Quercetin Remodels Tumor Microenvironment for Robust Chemoimmunotherapy
by: Yiping Li, et al.
Published: (2026)
by: Yiping Li, et al.
Published: (2026)
Tumor Microenvironment Specific Regulation Ca‐Fe‐Nanospheres for Ferroptosis‐Promoted Domino Synergistic Therapy and Tumor Immune Response
by: Xu Chu, et al.
Published: (2024)
by: Xu Chu, et al.
Published: (2024)
Multipath Synergistic Immune Activation of Hydrogels Delivering STING Agonist and siXkr8 for Long‐Lasting Colorectal Cancer Therapy
by: Ning Yang, et al.
Published: (2025)
by: Ning Yang, et al.
Published: (2025)
HA Self‐Assembled Dual‐Drug‐Loaded Nanoparticles: Integrating Multitargeted Tumor Therapy and Immune Microenvironment Remodeling via Phototherapy and Apoptosis
by: Lixuan Zang, et al.
Published: (2025)
by: Lixuan Zang, et al.
Published: (2025)
De Novo Design of Structure‐Tunable Multivalent Targeting Chimeras for Tumor‐Targeted PD‐L1 Degradation and Potentiated Cancer Immunotherapy
by: Huiling Zhou, et al.
Published: (2025)
by: Huiling Zhou, et al.
Published: (2025)
De Novo Design of Structure‐Tunable Multivalent Targeting Chimeras for Tumor‐Targeted PD‐L1 Degradation and Potentiated Cancer Immunotherapy
by: Huiling Zhou, et al.
Published: (2025)
by: Huiling Zhou, et al.
Published: (2025)
Activated Dendritic Cell Membrane‐Engineered Nanoformulation of Metallo‐Immunomodulators as Lysosome‐Targeted Adjuvants for Synergistic Cancer Immunotherapy
by: Heying Chen, et al.
Published: (2025)
by: Heying Chen, et al.
Published: (2025)
An Ultrasound‐Responsive Pickering‐Like Emulsion for Dual‐Amplified Sonodynamic/Cuproptosis Synergistic Therapy via Tumor Microenvironment Remodeling
by: Xue Jiang, et al.
Published: (2026)
by: Xue Jiang, et al.
Published: (2026)
Single Atom Catalysts Remodel Tumor Microenvironment for Augmented Sonodynamic Immunotherapy
by: Bijiang Geng, et al.
Published: (2024)
by: Bijiang Geng, et al.
Published: (2024)
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
by: Wanrong Wang, et al.
Published: (2026)
by: Wanrong Wang, et al.
Published: (2026)
Localized Delivery of Anti‐CD40/PD‐1 Immunotherapy via a Polymeric Implant is Efficacious, Remodels the Tumor Immune Microenvironment and Improves Safety in a PDAC Mouse Model
by: Elahe Minaei, et al.
Published: (2025)
by: Elahe Minaei, et al.
Published: (2025)
Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual‐Targeting BMI1 for Senescence Induction and CSN5 for PD‐L1 Degradation
by: Hongmei Hu, et al.
Published: (2024)
by: Hongmei Hu, et al.
Published: (2024)
Extracellularly Activated Logic‐Gated DNA Nanodevice for Molecular Transport via Reprogrammed Transferrin Receptor Trafficking
by: Peng‐Fei Dai, et al.
Published: (2025)
by: Peng‐Fei Dai, et al.
Published: (2025)
A Self‐Reinforcing Photonanocatalytic Platform Remodels Tumor Microenvironment for Synergistic Apoptosis/Ferroptosis Therapy in Liver Cancer
by: Xiaoling Zhang, et al.
Published: (2026)
by: Xiaoling Zhang, et al.
Published: (2026)
5‐ FU Resistance Facilitates Immune Evasion in Esophageal Squamous Cell Carcinoma Through ADAM10 ‐Mediated PD ‐ L1 Shedding and Tumour Microenvironment Remodelling
by: Bangwu Cai, et al.
Published: (2025)
by: Bangwu Cai, et al.
Published: (2025)
Similar Items
-
Inhibitory Microenvironment Remodeling Enhances STING Activation for Solid Tumor Immunotherapy
by: Wenming Fang, et al.
Published: (2025) -
Lysosome‐Targeting Bacterial Outer Membrane Vesicles for Tumor Specific Degradation of PD‐L1
by: Panpan Ji, et al.
Published: (2024) -
Mitochondria‐Targeted Nanoadjuvants Induced Multi‐Functional Immune‐Microenvironment Remodeling to Sensitize Tumor Radio‐Immunotherapy
by: Zaigang Zhou, et al.
Published: (2024) -
Engineering Bimetallic Polyphenol for Mild Photothermal Osteosarcoma Therapy and Immune Microenvironment Remodeling by Activating Pyroptosis and cGAS‐STING Pathway
by: Kaiyuan Liu, et al.
Published: (2024) -
Engineering a Tumor‐Targeted MgH 2 @Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation
by: Xuyu Gu, et al.
Published: (2026)