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| Main Authors: | , , , , , |
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| Format: | Artículo Open Access |
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Wiley
2025
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| Online Access: | https://bjui-journals.onlinelibrary.wiley.com/doi/10.1002/bco2.486 |
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| _version_ | 1867021622246899713 |
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| author | Alfred Honoré Karsten Gravdal Patrick Juliebø‐Jones Lars Anders Rokne Reisæter Christian Beisland Christian Arvei Moen |
| author_facet | Alfred Honoré Karsten Gravdal Patrick Juliebø‐Jones Lars Anders Rokne Reisæter Christian Beisland Christian Arvei Moen Alfred Honoré Karsten Gravdal Patrick Juliebø‐Jones Lars Anders Rokne Reisæter Christian Beisland Christian Arvei Moen |
| collection | Wiley Open Access |
| contents | Concordance with final pathology when transitioning from standard transrectal to cognitive targeted transperineal prostate biopsy Alfred Honoré Karsten Gravdal Patrick Juliebø‐Jones Lars Anders Rokne Reisæter Christian Beisland Christian Arvei Moen BJUI Compass AbstractObjectiveTransrectal (TR) prostate biopsy is being increasingly abandoned in favour of a transperineal (TP) approach as well as a targeted biopsy only of the index lesion(s). It remains underreported how these changes could impact concordance at final pathology. We aimed to evaluate the impact of transitioning from standard transrectal (sTR) to cognitive targeted transperineal (cog‐tTP) biopsy on final pathology including concordance and upgrading.Material and methodsAnalysis of consecutive patients undergoing prostate biopsy and prostatectomy (RP) between January 2018 and May 2022 at a tertiary centre in Western Norway.ResultsThere were 210 and 239 patients in the sTR and cog‐tTP groups, respectively. The mean [IQR] number of biopsies decreased from 12 [4–12] to 3 [3–4] (p < 0.001). The overall rate of concordance between biopsy and final pathology was 64% in both groups (Table 3, Figure 1). 24% Twenty‐four per cent (cog‐tTP) versus 19% (sTR) had grade group (GG) upgrading, while 12% versus 17% were downgraded (p = 0.2). Regarding positive surgical margins (PSMs) that were >3 mm in extension, there were only 3.3% and 2.1% in the sTR and cog‐tTP groups, respectively (p = 0.4). For surgical outcomes associated with RP, no differences in terms of postoperative complications between the groups were found (cog‐tTP:10% vs. sTR:6%, p = 0.10).ConclusionTransitioning from sTR biopsy to targeted cog‐tTP biopsy does not compromise concordance at final pathology nor does it increase the risk of tumour upgrading. 10.1002/bco2.486 http://creativecommons.org/licenses/by/4.0/ |
| doi_str_mv | 10.1002/bco2.486 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_bco2_486 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| publishDate | 2025 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Concordance with final pathology when transitioning from standard transrectal to cognitive targeted transperineal prostate biopsy Alfred Honoré Karsten Gravdal Patrick Juliebø‐Jones Lars Anders Rokne Reisæter Christian Beisland Christian Arvei Moen BJUI Compass Concordance with final pathology when transitioning from standard transrectal to cognitive targeted transperineal prostate biopsy Alfred Honoré Karsten Gravdal Patrick Juliebø‐Jones Lars Anders Rokne Reisæter Christian Beisland Christian Arvei Moen BJUI Compass AbstractObjectiveTransrectal (TR) prostate biopsy is being increasingly abandoned in favour of a transperineal (TP) approach as well as a targeted biopsy only of the index lesion(s). It remains underreported how these changes could impact concordance at final pathology. We aimed to evaluate the impact of transitioning from standard transrectal (sTR) to cognitive targeted transperineal (cog‐tTP) biopsy on final pathology including concordance and upgrading.Material and methodsAnalysis of consecutive patients undergoing prostate biopsy and prostatectomy (RP) between January 2018 and May 2022 at a tertiary centre in Western Norway.ResultsThere were 210 and 239 patients in the sTR and cog‐tTP groups, respectively. The mean [IQR] number of biopsies decreased from 12 [4–12] to 3 [3–4] (p < 0.001). The overall rate of concordance between biopsy and final pathology was 64% in both groups (Table 3, Figure 1). 24% Twenty‐four per cent (cog‐tTP) versus 19% (sTR) had grade group (GG) upgrading, while 12% versus 17% were downgraded (p = 0.2). Regarding positive surgical margins (PSMs) that were >3 mm in extension, there were only 3.3% and 2.1% in the sTR and cog‐tTP groups, respectively (p = 0.4). For surgical outcomes associated with RP, no differences in terms of postoperative complications between the groups were found (cog‐tTP:10% vs. sTR:6%, p = 0.10).ConclusionTransitioning from sTR biopsy to targeted cog‐tTP biopsy does not compromise concordance at final pathology nor does it increase the risk of tumour upgrading. 10.1002/bco2.486 http://creativecommons.org/licenses/by/4.0/ |
| title | Concordance with final pathology when transitioning from standard transrectal to cognitive targeted transperineal prostate biopsy |
| topic | BJUI Compass |
| url | https://bjui-journals.onlinelibrary.wiley.com/doi/10.1002/bco2.486 |