Outcomes of Aquablation in BPH with bladder stones: Analysis of the ICARUS database

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Main Authors: Joshua D. Cabral, Margaret Gannon, Gregory Raster, David J. Nusbaum, David Bouhadana, Adel Arezki, Aalya Hamouda, Anouk Leathead, Ilan Ohana, Rosie Foucault, Iman Sadri, Jeffrey A. Sioufi, Nick Lee, Tarek Benzouak, Liam Murad, Nicholas J. Corsi, John Klein, Inderjit Singh, James Kearns, Cecilia Chang, Juan Justo Quintas, Kevin C. Zorn, Tiago Rodrigues, Shawn H. Marhamati, Brian T. Helfand, Alexander P. Glaser
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Published: Wiley 2026
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author Joshua D. Cabral
Margaret Gannon
Gregory Raster
David J. Nusbaum
David Bouhadana
Adel Arezki
Aalya Hamouda
Anouk Leathead
Ilan Ohana
Rosie Foucault
Iman Sadri
Jeffrey A. Sioufi
Nick Lee
Tarek Benzouak
Liam Murad
Nicholas J. Corsi
John Klein
Inderjit Singh
James Kearns
Cecilia Chang
Juan Justo Quintas
Kevin C. Zorn
Tiago Rodrigues
Shawn H. Marhamati
Brian T. Helfand
Alexander P. Glaser
author_facet Joshua D. Cabral
Margaret Gannon
Gregory Raster
David J. Nusbaum
David Bouhadana
Adel Arezki
Aalya Hamouda
Anouk Leathead
Ilan Ohana
Rosie Foucault
Iman Sadri
Jeffrey A. Sioufi
Nick Lee
Tarek Benzouak
Liam Murad
Nicholas J. Corsi
John Klein
Inderjit Singh
James Kearns
Cecilia Chang
Juan Justo Quintas
Kevin C. Zorn
Tiago Rodrigues
Shawn H. Marhamati
Brian T. Helfand
Alexander P. Glaser
Joshua D. Cabral
Margaret Gannon
Gregory Raster
David J. Nusbaum
David Bouhadana
Adel Arezki
Aalya Hamouda
Anouk Leathead
Ilan Ohana
Rosie Foucault
Iman Sadri
Jeffrey A. Sioufi
Nick Lee
Tarek Benzouak
Liam Murad
Nicholas J. Corsi
John Klein
Inderjit Singh
James Kearns
Cecilia Chang
Juan Justo Quintas
Kevin C. Zorn
Tiago Rodrigues
Shawn H. Marhamati
Brian T. Helfand
Alexander P. Glaser
collection Wiley Open Access
contents Outcomes of Aquablation in BPH with bladder stones: Analysis of the ICARUS database Joshua D. Cabral Margaret Gannon Gregory Raster David J. Nusbaum David Bouhadana Adel Arezki Aalya Hamouda Anouk Leathead Ilan Ohana Rosie Foucault Iman Sadri Jeffrey A. Sioufi Nick Lee Tarek Benzouak Liam Murad Nicholas J. Corsi John Klein Inderjit Singh James Kearns Cecilia Chang Juan Justo Quintas Kevin C. Zorn Tiago Rodrigues Shawn H. Marhamati Brian T. Helfand Alexander P. Glaser BJUI Compass Abstract Objective The purpose of this study is investigate the clinical outcomes of men with benign prostatic hyperplasia (BPH) and bladder stones treated concomitantly with Aquablation and bladder stone removal in an international, multi‐institutional cohort. Patients and Methods We performed a retrospective analysis of men who underwent Aquablation between 2018 and 2024. Patients were divided into two cohorts: men with bladder stones and those without. Outcomes assessed included baseline demographics and variables (medication use, prostate volume, prior BPH surgery), operative characteristics (OR time, transfusion requirement, complications), and functional outcomes were measured by the International Prostate Symptom Score (IPSS), peak urinary flow rate ( Q max ) and PVR at regular intervals over 24 months. Results A total of 1885 men were analysed, including 60 men with bladder stones and 1825 without. Patients with bladder stones had higher rates of prior BPH surgery (15% vs. 5.5%, p  = 0.015) and pre‐operative urinary retention (28.3% vs. 14.8%, p  = 0.004) as well as larger prostate volumes (98.6 ml vs. 77 ml, p  < 0.0001). Total operative time was longer in the bladder stone group (76.5 mins vs. 55.0 mins, p  < 0.001), but there were no significant differences in Aquablation time or bleeding complications including transfusions. There was also no difference in improvements in IPSS, Q max and PVR post‐operatively. Conclusion This study demonstrates that Aquablation is safe and effective in the management of BPH regardless of concomitant bladder stone treatment. 10.1002/bco2.70156 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1002/bco2.70156
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id wiley_oa_10_1002_bco2_70156
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license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2026
publisher Wiley
record_format wiley_oa
spellingShingle Outcomes of Aquablation in BPH with bladder stones: Analysis of the ICARUS database
Joshua D. Cabral
Margaret Gannon
Gregory Raster
David J. Nusbaum
David Bouhadana
Adel Arezki
Aalya Hamouda
Anouk Leathead
Ilan Ohana
Rosie Foucault
Iman Sadri
Jeffrey A. Sioufi
Nick Lee
Tarek Benzouak
Liam Murad
Nicholas J. Corsi
John Klein
Inderjit Singh
James Kearns
Cecilia Chang
Juan Justo Quintas
Kevin C. Zorn
Tiago Rodrigues
Shawn H. Marhamati
Brian T. Helfand
Alexander P. Glaser
BJUI Compass
Outcomes of Aquablation in BPH with bladder stones: Analysis of the ICARUS database Joshua D. Cabral Margaret Gannon Gregory Raster David J. Nusbaum David Bouhadana Adel Arezki Aalya Hamouda Anouk Leathead Ilan Ohana Rosie Foucault Iman Sadri Jeffrey A. Sioufi Nick Lee Tarek Benzouak Liam Murad Nicholas J. Corsi John Klein Inderjit Singh James Kearns Cecilia Chang Juan Justo Quintas Kevin C. Zorn Tiago Rodrigues Shawn H. Marhamati Brian T. Helfand Alexander P. Glaser BJUI Compass Abstract Objective The purpose of this study is investigate the clinical outcomes of men with benign prostatic hyperplasia (BPH) and bladder stones treated concomitantly with Aquablation and bladder stone removal in an international, multi‐institutional cohort. Patients and Methods We performed a retrospective analysis of men who underwent Aquablation between 2018 and 2024. Patients were divided into two cohorts: men with bladder stones and those without. Outcomes assessed included baseline demographics and variables (medication use, prostate volume, prior BPH surgery), operative characteristics (OR time, transfusion requirement, complications), and functional outcomes were measured by the International Prostate Symptom Score (IPSS), peak urinary flow rate ( Q max ) and PVR at regular intervals over 24 months. Results A total of 1885 men were analysed, including 60 men with bladder stones and 1825 without. Patients with bladder stones had higher rates of prior BPH surgery (15% vs. 5.5%, p  = 0.015) and pre‐operative urinary retention (28.3% vs. 14.8%, p  = 0.004) as well as larger prostate volumes (98.6 ml vs. 77 ml, p  < 0.0001). Total operative time was longer in the bladder stone group (76.5 mins vs. 55.0 mins, p  < 0.001), but there were no significant differences in Aquablation time or bleeding complications including transfusions. There was also no difference in improvements in IPSS, Q max and PVR post‐operatively. Conclusion This study demonstrates that Aquablation is safe and effective in the management of BPH regardless of concomitant bladder stone treatment. 10.1002/bco2.70156 http://creativecommons.org/licenses/by/4.0/
title Outcomes of Aquablation in BPH with bladder stones: Analysis of the ICARUS database
topic BJUI Compass
url https://bjui-journals.onlinelibrary.wiley.com/doi/10.1002/bco2.70156