Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2‐year experience in a dedicated complex‐UTI clinic

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Main Authors: Pragnitha Chitteti, Ekpeno Inyang, Ahmed Ghonaimy, Jayne Morris‐Laverick, Stephanie Bezemer, Igor Kubelka, Victoria McCune, Mehwash Nadeem
Format: Artículo Open Access
Published: Wiley 2026
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author Pragnitha Chitteti
Ekpeno Inyang
Ahmed Ghonaimy
Jayne Morris‐Laverick
Stephanie Bezemer
Igor Kubelka
Victoria McCune
Mehwash Nadeem
author_facet Pragnitha Chitteti
Ekpeno Inyang
Ahmed Ghonaimy
Jayne Morris‐Laverick
Stephanie Bezemer
Igor Kubelka
Victoria McCune
Mehwash Nadeem
Pragnitha Chitteti
Ekpeno Inyang
Ahmed Ghonaimy
Jayne Morris‐Laverick
Stephanie Bezemer
Igor Kubelka
Victoria McCune
Mehwash Nadeem
collection Wiley Open Access
contents Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2‐year experience in a dedicated complex‐UTI clinic Pragnitha Chitteti Ekpeno Inyang Ahmed Ghonaimy Jayne Morris‐Laverick Stephanie Bezemer Igor Kubelka Victoria McCune Mehwash Nadeem BJUI Compass Abstract Objectives This work aimed to assess treatment outcomes in patients with recurrent urinary tract infections (rUTIs) managed in a dedicated multidisciplinary complex‐UTI clinic. In addition, this work aimed to evaluate the impact of tailored interventions on patient‐reported outcomes, including quality of life (QoL) and symptomatic improvement. Materials and Methods A 2‐year, single‐centre, prospective observational cohort study was conducted in a dedicated tertiary care UTI clinic. A multidisciplinary team comprising urologists, microbiologists and specialist nurses developed individualized management plans based on thorough assessments, including patient history, physical examination and necessary investigations. Data variables included patient demographics, urine culture results with antibiotic sensitivities, investigations performed and the treatment options administered. The minimum follow‐up period was 6 months after the implementation of treatment in the clinic. Pretreatment and posttreatment QoL were assessed, along with posttreatment Patient Global Impression of Improvement (PGI‐I) scores. Results A total of 211 patients (mean age: 58.3 years, 89.6% female) were included. First‐ and second‐line treatments were effective for 71% of patients, while 29% required tertiary interventions. Post‐treatment, 81% of patients reported good‐to‐excellent improvement on the PGI‐I scale, and 70% achieved good‐to‐excellent QoL. Overall treatment success, defined as reduced UTI frequency or symptom resolution, was reported in 87.7% of patients. Factors such as immunosuppression and history of hospital admission for urosepsis were associated with poor treatment outcomes with statistical significance. Conclusion Dedicated multidisciplinary UTI clinics significantly improve treatment outcomes and QoL for patients with rUTIs. The findings support broader adoption of multidisciplinary approaches, emphasizing early intervention and tailored care to optimize clinical efficiency and enhance the patient experience. 10.1002/bco2.70177 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1002/bco2.70177
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license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2026
publisher Wiley
record_format wiley_oa
spellingShingle Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2‐year experience in a dedicated complex‐UTI clinic
Pragnitha Chitteti
Ekpeno Inyang
Ahmed Ghonaimy
Jayne Morris‐Laverick
Stephanie Bezemer
Igor Kubelka
Victoria McCune
Mehwash Nadeem
BJUI Compass
Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2‐year experience in a dedicated complex‐UTI clinic Pragnitha Chitteti Ekpeno Inyang Ahmed Ghonaimy Jayne Morris‐Laverick Stephanie Bezemer Igor Kubelka Victoria McCune Mehwash Nadeem BJUI Compass Abstract Objectives This work aimed to assess treatment outcomes in patients with recurrent urinary tract infections (rUTIs) managed in a dedicated multidisciplinary complex‐UTI clinic. In addition, this work aimed to evaluate the impact of tailored interventions on patient‐reported outcomes, including quality of life (QoL) and symptomatic improvement. Materials and Methods A 2‐year, single‐centre, prospective observational cohort study was conducted in a dedicated tertiary care UTI clinic. A multidisciplinary team comprising urologists, microbiologists and specialist nurses developed individualized management plans based on thorough assessments, including patient history, physical examination and necessary investigations. Data variables included patient demographics, urine culture results with antibiotic sensitivities, investigations performed and the treatment options administered. The minimum follow‐up period was 6 months after the implementation of treatment in the clinic. Pretreatment and posttreatment QoL were assessed, along with posttreatment Patient Global Impression of Improvement (PGI‐I) scores. Results A total of 211 patients (mean age: 58.3 years, 89.6% female) were included. First‐ and second‐line treatments were effective for 71% of patients, while 29% required tertiary interventions. Post‐treatment, 81% of patients reported good‐to‐excellent improvement on the PGI‐I scale, and 70% achieved good‐to‐excellent QoL. Overall treatment success, defined as reduced UTI frequency or symptom resolution, was reported in 87.7% of patients. Factors such as immunosuppression and history of hospital admission for urosepsis were associated with poor treatment outcomes with statistical significance. Conclusion Dedicated multidisciplinary UTI clinics significantly improve treatment outcomes and QoL for patients with rUTIs. The findings support broader adoption of multidisciplinary approaches, emphasizing early intervention and tailored care to optimize clinical efficiency and enhance the patient experience. 10.1002/bco2.70177 http://creativecommons.org/licenses/by/4.0/
title Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2‐year experience in a dedicated complex‐UTI clinic
topic BJUI Compass
url https://bjui-journals.onlinelibrary.wiley.com/doi/10.1002/bco2.70177