Multi‐Scale Hybrid Modeling to Predict Cell Culture Process With Metabolic Phase Transitions
Fuente:
Wiley Open Access
Guardado en:
| Autores principales: | Keqi Wang, Sarah W. Harcum, Wei Xie |
|---|---|
| Formato: | Artículo Open Access |
| Publicado: |
Wiley
2026
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction
por: Keqi Wang, et al.
Publicado: (2026)
por: Keqi Wang, et al.
Publicado: (2026)
Perfusion Process Intensification for Lentivirus Production Using a Novel Scale‐Down Model
por: Maximilian Klimpel, et al.
Publicado: (2024)
por: Maximilian Klimpel, et al.
Publicado: (2024)
Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes
por: Austin K. Feeney, et al.
Publicado: (2026)
por: Austin K. Feeney, et al.
Publicado: (2026)
A Required Sensitivity Analysis for Predictive Reliability of Genome–Scale Metabolic Networks: Probing Biomass, Nutrient Conditions, and Specialised Metabolism With Penicillium rubens as a Case Study
por: Delphine Nègre, et al.
Publicado: (2026)
por: Delphine Nègre, et al.
Publicado: (2026)
In Situ Microscopy for Real‐Time Visualization of Microcarrier Cell Cultures for Live Virus Vaccine Process Development
por: Justin P. Lomont, et al.
Publicado: (2026)
por: Justin P. Lomont, et al.
Publicado: (2026)
Augmentation Models of Stem Cell Culture Data for the Application of Machine Learning
por: Owen Skriloff, et al.
Publicado: (2025)
por: Owen Skriloff, et al.
Publicado: (2025)
Nicotinamide Reverses the Warburg Effect in CHO Cell Culture
por: James Morrissey, et al.
Publicado: (2026)
por: James Morrissey, et al.
Publicado: (2026)
A Mathematical Model for Determining Probabilistic Design Space in Mesenchymal Stem Cell Passage Culture
por: Keita Hirono, et al.
Publicado: (2025)
por: Keita Hirono, et al.
Publicado: (2025)
Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells
por: Kate E. Meeson, et al.
Publicado: (2025)
por: Kate E. Meeson, et al.
Publicado: (2025)
Defining Golden Batches in Biomanufacturing Processes From Internal Metabolic Activity to Detect Process Changes That May Affect Product Quality
por: Xin Bush, et al.
Publicado: (2024)
por: Xin Bush, et al.
Publicado: (2024)
Metabolic Engineering of Streptomyces leeuwenhoekii C34 T to Increase Chaxamycin Production Based on the i VR1007 Genome‐Scale Model
por: Anett Rubio, et al.
Publicado: (2025)
por: Anett Rubio, et al.
Publicado: (2025)
On the Prediction of pDNA Productivity Across Diverse Bioprocesses Using Ensemble Hybrid Models
por: Nikolaos Stratis, et al.
Publicado: (2026)
por: Nikolaos Stratis, et al.
Publicado: (2026)
Integrating Green Process Engineering With Whole‐Cell Catalysis to Intensify Sustainable Glucaric Acid Production
por: Xia Hua, et al.
Publicado: (2026)
por: Xia Hua, et al.
Publicado: (2026)
Unsupervised Machine Learning‐Based Process Analytical Tools for Near Real‐Time Cell Morphology Analysis During CAR‐T Cell Manufacturing
por: Nidhi G. Thite, et al.
Publicado: (2025)
por: Nidhi G. Thite, et al.
Publicado: (2025)
Single Cell Protein Production From Ethanol: Model‐Based Bioreactor Operation at Industrial Scale
por: Eduardo Almeida Benalcázar, et al.
Publicado: (2025)
por: Eduardo Almeida Benalcázar, et al.
Publicado: (2025)
Tissue‐Specific Differential Flux Analysis Reveals Metabolic Insights Into Pancreatic β‐Cell Dysfunction in Type 2 Diabetes
por: Satyajit Beura, et al.
Publicado: (2026)
por: Satyajit Beura, et al.
Publicado: (2026)
Customizable Stacks for Enhanced Cell Culture in 3D Tissue Engineering Using Alginate Membranes
por: Patipat Kamdenlek, et al.
Publicado: (2025)
por: Patipat Kamdenlek, et al.
Publicado: (2025)
Research on Intelligent Monitoring and Concentration Prediction for Penicillin Fermentation Process
por: Yin Zhang, et al.
Publicado: (2024)
por: Yin Zhang, et al.
Publicado: (2024)
3D Culture in Functionalized FN‐Silk Networks Facilitate Proliferation, Differentiation and Phenotypic Stability of Mature Human Primary Cells and Stem Cells
por: Astrid Källén, et al.
Publicado: (2025)
por: Astrid Källén, et al.
Publicado: (2025)
Process Intensification for Recombinant Protein Production in E. coli via Identification of Active Nodes in Cellular Metabolism and Dynamic Flux Balance Analysis
por: Hardik Dodia, et al.
Publicado: (2025)
por: Hardik Dodia, et al.
Publicado: (2025)
Impact of Hormone on Growth and GA 3 Regulation of Anthocyanin Biosynthesis in Suspension‐Culture Cells of Cyclocarya paliurus
por: Chuanqing Pan, et al.
Publicado: (2024)
por: Chuanqing Pan, et al.
Publicado: (2024)
Genetically Programmed Control of Overflow Metabolism
por: Lærke M. Jensen, et al.
Publicado: (2026)
por: Lærke M. Jensen, et al.
Publicado: (2026)
Constraint‐Based Metabolic Modeling of Synechococcus elongatus PCC 11801 and PCC 11802 for Photosynthetic Biomanufacturing
por: Lokesh Venkatesh Babu, et al.
Publicado: (2025)
por: Lokesh Venkatesh Babu, et al.
Publicado: (2025)
De Novo Biosynthesis of 1,5‐Pentanediol by Metabolically Engineered Escherichia coli
por: Chen Ma, et al.
Publicado: (2026)
por: Chen Ma, et al.
Publicado: (2026)
Combinatorial Metabolic Engineering for Enhanced Gibberellic Acid Biosynthesis in Fusarium fujikuroi
por: Xia Ke, et al.
Publicado: (2025)
por: Xia Ke, et al.
Publicado: (2025)
Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation
por: Thomas Kruse, et al.
Publicado: (2026)
por: Thomas Kruse, et al.
Publicado: (2026)
Reinforcement Learning for Robust Dynamic Metabolic Control
por: Sebastián Espinel‐Ríos, et al.
Publicado: (2025)
por: Sebastián Espinel‐Ríos, et al.
Publicado: (2025)
Accelerated Adeno Associated Virus Upstream Process Development From High‐Throughput Systems to Clinical Scale
por: Angela Andaluz, et al.
Publicado: (2025)
por: Angela Andaluz, et al.
Publicado: (2025)
Bead to Bead Transfer, an Efficient Strategy to Scale‐up the Mesenchymal Stromal Cells‐Derived Secretome Bioproduction
por: Bastien Thauvin, et al.
Publicado: (2025)
por: Bastien Thauvin, et al.
Publicado: (2025)
Correction to Accelerated Adeno Associated Virus Upstream Process Development From High‐Throughput Systems to Clinical Scale
Publicado: (2025)
Publicado: (2025)
Application of Multiple Base‐Editing Mediated by Polycistronic tRNA‐gRNA‐Processing System in Pig Cells
por: Wudi Zhao, et al.
Publicado: (2025)
por: Wudi Zhao, et al.
Publicado: (2025)
CRISPR‐Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin
por: Jackson K. B. Cahn, et al.
Publicado: (2025)
por: Jackson K. B. Cahn, et al.
Publicado: (2025)
Astrocytes Protect Brain Metastatic Breast Cancer Cells From Chemotherapy Through CX43 Dependent STAT1 Signaling in Co‐Culture Spheroids
por: Venu Yakati, et al.
Publicado: (2026)
por: Venu Yakati, et al.
Publicado: (2026)
Metabolic Engineering and Adaptive Evolution of Escherichia coli for Enhanced Conversion of D‑Xylose to D‐Glucaric Acid Mediated by Methanol
por: Wei‐Xiang Chen, et al.
Publicado: (2025)
por: Wei‐Xiang Chen, et al.
Publicado: (2025)
Multiplexed Metabolic and Protein Engineering for D‐Limonene Overproduction in Saccharomyces cerevisiae
por: Ruowei Hua, et al.
Publicado: (2025)
por: Ruowei Hua, et al.
Publicado: (2025)
Integrating Ensemble NSGA‐II for Multi‐Objective Process Optimization: Refolding of Proinsulin as a Case Study
por: Rashmi Sharma, et al.
Publicado: (2025)
por: Rashmi Sharma, et al.
Publicado: (2025)
Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes
por: Eric VanArsdale, et al.
Publicado: (2026)
por: Eric VanArsdale, et al.
Publicado: (2026)
Controlling Human Stem Cell‐Derived Islet Composition Using Magnetic Sorting
por: Allison B. Kelley, et al.
Publicado: (2025)
por: Allison B. Kelley, et al.
Publicado: (2025)
RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets
por: Merve Yarıcı, et al.
Publicado: (2025)
por: Merve Yarıcı, et al.
Publicado: (2025)
Drug Metabolism by Engineered Toluene o ‐Xylene Monooxygenases of Pseudomonas sp. OX1
por: Noella Younan, et al.
Publicado: (2025)
por: Noella Younan, et al.
Publicado: (2025)
Ejemplares similares
-
A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction
por: Keqi Wang, et al.
Publicado: (2026) -
Perfusion Process Intensification for Lentivirus Production Using a Novel Scale‐Down Model
por: Maximilian Klimpel, et al.
Publicado: (2024) -
Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes
por: Austin K. Feeney, et al.
Publicado: (2026) -
A Required Sensitivity Analysis for Predictive Reliability of Genome–Scale Metabolic Networks: Probing Biomass, Nutrient Conditions, and Specialised Metabolism With Penicillium rubens as a Case Study
por: Delphine Nègre, et al.
Publicado: (2026) -
In Situ Microscopy for Real‐Time Visualization of Microcarrier Cell Cultures for Live Virus Vaccine Process Development
por: Justin P. Lomont, et al.
Publicado: (2026)