Barrigenol‐Like Triterpenoid Saponins From the Husks of Xanthoceras sorbifolia Bunge and Their Cytotoxicity
Fuente:
Wiley Open Access
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | Artículo Open Access |
| Publicado: |
Wiley
2025
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1867020945223319552 |
|---|---|
| author | Muke Tao Xinghao Dong Zhe Wang Dali Meng Yi Zhang Li Guo |
| author_facet | Muke Tao Xinghao Dong Zhe Wang Dali Meng Yi Zhang Li Guo Muke Tao Xinghao Dong Zhe Wang Dali Meng Yi Zhang Li Guo |
| collection | Wiley Open Access |
| contents | Barrigenol‐Like Triterpenoid Saponins From the Husks of Xanthoceras sorbifolia Bunge and Their Cytotoxicity Muke Tao Xinghao Dong Zhe Wang Dali Meng Yi Zhang Li Guo Chemistry & Biodiversity ABSTRACTThe phytochemical study on Xanthoceras sorbifolium Bunge husks, a folk medicinal plant in China, led to the isolation of ten saponins including four new compounds from this plant. Their structures were elucidated based on physical and chemical properties and spectral data analysis. The cytotoxic effects of compounds 1–5 were evaluated by four different human cancer cell lines: HCT‐116 cell line, MCF‐7 cell line, ASG cell line, and Hep3B cell line. Most of the tested compounds showed a certain degree of growth inhibition effect on all four cell lines. Notably, compound 3 demonstrated the highest cytotoxicity to all four cell lines, and compound 4 has highly selective anti‐tumor activity on MCF‐7 cells. 10.1002/cbdv.202500708 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1002/cbdv.202500708 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_cbdv_202500708 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2025 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Barrigenol‐Like Triterpenoid Saponins From the Husks of Xanthoceras sorbifolia Bunge and Their Cytotoxicity Muke Tao Xinghao Dong Zhe Wang Dali Meng Yi Zhang Li Guo Chemistry & Biodiversity Barrigenol‐Like Triterpenoid Saponins From the Husks of Xanthoceras sorbifolia Bunge and Their Cytotoxicity Muke Tao Xinghao Dong Zhe Wang Dali Meng Yi Zhang Li Guo Chemistry & Biodiversity ABSTRACTThe phytochemical study on Xanthoceras sorbifolium Bunge husks, a folk medicinal plant in China, led to the isolation of ten saponins including four new compounds from this plant. Their structures were elucidated based on physical and chemical properties and spectral data analysis. The cytotoxic effects of compounds 1–5 were evaluated by four different human cancer cell lines: HCT‐116 cell line, MCF‐7 cell line, ASG cell line, and Hep3B cell line. Most of the tested compounds showed a certain degree of growth inhibition effect on all four cell lines. Notably, compound 3 demonstrated the highest cytotoxicity to all four cell lines, and compound 4 has highly selective anti‐tumor activity on MCF‐7 cells. 10.1002/cbdv.202500708 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Barrigenol‐Like Triterpenoid Saponins From the Husks of Xanthoceras sorbifolia Bunge and Their Cytotoxicity |
| topic | Chemistry & Biodiversity |
| url | https://onlinelibrary.wiley.com/doi/10.1002/cbdv.202500708 |