Imagen de Portada

Design, Synthesis, and Biological Evaluation of Benzimidazole‐Pyrazole Hybrids as Aromatase Inhibitors for Breast Cancer Therapy

Fuente: Wiley Open Access

Guardado en:

Detalles Bibliográficos
Autores principales:	Supriya Sharma, Jay Prakash Soni, Milind J. Umekar, Uma Dhiraj Kabra
Formato:	Artículo Open Access
Publicado:	Wiley 2026
Materias:	Chemistry & Biodiversity
Acceso en línea:	Acceder al recurso
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Design, Synthesis, Biological Evaluation, and Computational Studies of Pyrazine‐1,3,4‐Oxadiazole Analogs as Potential Antitubercular Agents
por: Asha Ganesh Suryawanshi, et al.
Publicado: (2025)

Structure‐Guided Identification of Novel Aromatase Inhibitors Targeting Breast Carcinoma
por: Priyanka Yadav, et al.
Publicado: (2024)

Novel Pyrazole‐Chalcone Hybrids: Synthesis and Computational Insights Against Breast Cancer
por: Pratap S. Dabhade, et al.
Publicado: (2024)

Molecular Docking, Synthesis and Biological Evaluation of New Benzimidazole‐Pyridine Derivatives as Potential Aromatase Inhibitor for the Treatment of Cancer
por: Prafulla Sabale, et al.
Publicado: (2024)

Design and Synthesis of Pyrazole Carboxamide Derivatives as Selective Cholinesterase and Carbonic Anhydrase Inhibitors: Molecular Docking and Biological Evaluation
por: Mustafa Durgun, et al.
Publicado: (2024)

Design, Synthesis, and Antibacterial Evaluation of Hybrid Product of Benzimidazole and Isoxazole
por: Xingyu Bian, et al.
Publicado: (2025)

In Silico Screening of Flavonoids From Cycas as Potential Aromatase Inhibitors for Breast Cancer Therapy and Estimation of Total Flavonoid Content and LC–MS Analysis of Cycas revoluta Extract
por: Charu Bhutani, et al.
Publicado: (2025)

Synthesis and Molecular Docking of Curcumin‐Derived Pyrazole‐Thiazole Hybrids as Potent α‐Glucosidase Inhibitors
por: Jehan Y. Al‐Humaidi, et al.
Publicado: (2024)

Design, Synthesis, Anti‐Proliferative, and Apoptotic Assessment of Spirocyclopropyl Oxindole–Isatin Hybrids on Triple‐Negative Breast Cancer
por: Preeti, et al.
Publicado: (2024)

Design, Synthesis, and Biological Evaluation of Pyrazol‐5‐yl‐quinoline‐2‐carboxamide Derivatives as Potential Fungicidal Agents
por: Wei Wang, et al.
Publicado: (2025)

Innovative Pyrazole Hybrids: A New Era in Drug Discovery and Synthesis
por: Anjaneyulu Bendi, et al.
Publicado: (2024)

Design, Synthesis and Alpha‐glucosidase Inhibitory Effect of Pyrazole‐1,2,3‐Triazole Hybrids
por: Suprapaneni Sirisha, et al.
Publicado: (2025)

Design, Synthesis, and Biological Evaluation of New Improved Ferrostatin‐1 Derived Ferroptosis Inhibitors
por: Nai‐Yu Zhang, et al.
Publicado: (2024)

Synthesis, Crystal Structure, Characterization, In Vitro and In Silico Evaluation of Vanillin‐Pyrazole Heterocyclic Hybrids as Potent Antioxidants
por: Mohamed Adardour, et al.
Publicado: (2026)

Design and Synthesis of Propargyloxy Functionalized Pyrazole‐Based Aurones: Exploring Their Potent Anticancer Properties Against AGS and MCF‐7 Cell Lines
por: Ekta Lathwal, et al.
Publicado: (2024)

Design, Synthesis, and Biological Evaluation of New Substituted 5‐Aryl‐Oxadiazole‐based Derivatives as Acetylcholinesterase and Butyrylcholinesterase Inhibitors
por: Elahe Hadadianpour, et al.
Publicado: (2025)

Synthesis and Tyrosinase Inhibitory Activity of Novel Benzimidazole/Thiazolidin‐4‐one Hybrid Derivatives
por: Leen Mohammad Amin Farhan Khraisat, et al.
Publicado: (2024)

Biomass Derived Carbon Quantum Dots for the Green Synthesis of Aryl Semicarbazones and Their In Silico Evaluation
por: Sunita Teli, et al.
Publicado: (2026)

Design, Synthesis, Molecular Docking, and Biological Evaluation of Tanshinone IIA Derivatives as Antibreast Cancer Agents
por: Shuai Zhang, et al.
Publicado: (2026)

Aza‐BODIPY‐Derived Fluorescent Probe for Cancer Cell Imaging and Combined PDT/PTT Applications
por: Tavish Sharma, et al.
Publicado: (2026)

Synthesis, In vitro and In silico Studies of Novel Bis‐triazolopyridopyrimidines from Curcumin Analogues as Potential Aromatase Agents
por: Sobhi M. Gomha, et al.
Publicado: (2024)

New Quinazolinone‐Thiouracil Derivatives: Design, Synthesis, Anticancer Evaluation, and In Silico Analysis
por: Dolly Parmar, et al.
Publicado: (2024)

Design, Synthesis, and Biological Evaluation of Aminophenol–Quinazoline‐Based Derivatives as Antiproliferative Agents Against Colorectal Cancer
por: Sachin A. Dhawale, et al.
Publicado: (2026)

Exploring the Antimicrobial Potential of Novel 1,2,4−Triazole Conjugates with Pyrazole: Synthesis, Biological Activity and In Silico Docking
por: Ganesh Babu N. V. N. Kolukula, et al.
Publicado: (2024)

Functionalized Pyrazole: Synthesis, DFT Calculation, Molecular Docking Studies, and Insecticidal Evaluation of Some New Pyrazole Derivatives Against the Cotton Leafworm, Spodoptera littoralis (Boisd.)
por: Rania Ali El Hadi Mohamed, et al.
Publicado: (2025)

A 5‐Year Survey on Multiple Targeted Benzimidazole Hybrids
por: Ayşen Işik, et al.
Publicado: (2025)

Design, Synthesis, and Biological Evaluation of Coumarin–Thiobarbituric Acid Hybrids Targeting Breast Cancer
por: Paramjeet Kaur, et al.
Publicado: (2026)

Novel 2‐Alkoxy‐3‐Cyanopyridine Derivatives as Cholinesterase Inhibitors: Synthesis, Biological Evaluation, and In Silico Investigations
por: Ibtissem Kadi, et al.
Publicado: (2025)

Phytoconstituents of Gmelina Arborea as Potential Breast Cancer Inhibitors: LC‐MS/MS, Docking, MD Simulations, and In Vitro Evaluation
por: Dharipally Harini, et al.
Publicado: (2026)

Synthesis and Biological Evaluation of 1‐(4‐(Methylsulfonyl)Phenyl)‐5‐Phenyl‐1H‐Pyrazole‐4‐Carboxamides as Epidermal Growth Factor Receptor‐Targeting Anticancer Agents
por: Madhava Rao Bandaru, et al.
Publicado: (2025)

Design, Synthesis, and Bioactivity Evaluation of a Palmitoyltransferase Inhibitor Based on the PAP Structure
por: Yibo Zhang, et al.
Publicado: (2026)

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
por: Isadora M. G. Andrade, et al.
Publicado: (2025)

Design, Synthesis, Biological Evaluation and in Silico Studies of Curcumin Pyrrole Conjugates
por: Nishi Gandha Gogoi, et al.
Publicado: (2024)

New Sulfonate Ester‐Linked Fluorinated Hydrazone Derivatives as Multitarget Carbonic Anhydrase and Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, Molecular Docking and ADME Analysis
por: Berna Akış, et al.
Publicado: (2024)

Design, Synthesis, Biological Evaluation, and In Silico Study of N ‐(Pyrazin‐2‐yl)Alkyl/Aryl Amide Derivatives as Quorum Sensing Inhibitors Against Pseudomonas aeruginosa
por: Anand Yadav, et al.
Publicado: (2025)

A Structure‐Based Design Strategy with Pyrazole‐Pyridine Derivatives Targeting TNFα as Anti‐Inflammatory Agents: E‐Pharmacophore, Dynamic Simulation, Synthesis and In Vitro Evaluation
por: Debojyoti Halder, et al.
Publicado: (2024)

Synthesis and Biological Evaluations of the 1,3,5‐Triazine Derivatives as Cholinesterase Inhibitors, Antioxidant, and Biometal Chelators for Alzheimer's Disease
por: Fardin Mahdipanah, et al.
Publicado: (2026)

In silico Design, Synthesis and Biological Evaluation of Novel Thieno[3,2‐d]pyrimidine Derivatives for Cancer Therapy – A Preliminary Study on the Inhibitory Potential towards ATR Kinase Domain and PIKK Family
por: Samvel N. Sirakanyan, et al.
Publicado: (2024)

Synthesis, Biological Evaluation, and Computational Studies of Schiff's Base Derivatives of 4‐(4‐Amino‐5‐Mercapto‐4H‐1,2,4‐Triazol‐3‐Yl)Benzenesulfonamide as Cathepsin B Inhibitors
por: Monika, et al.
Publicado: (2024)

Design, Synthesis, and Anti‐Mycobacterial Evaluation of Triclosan‐Isoniazid Hybrids
por: Nikita Gupta, et al.
Publicado: (2024)