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| Hauptverfasser: | , , , , , , , , , , , , , , , |
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| Format: | Artículo Open Access |
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Wiley
2025
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| Online-Zugang: | https://onlinelibrary.wiley.com/doi/10.1002/ccd.31713 |
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Inhaltsangabe:
- Intravascular Lithotripsy for Calcific Coronary Bifurcations: Procedural Success and 1‐Year Clinical Outcomes Federico Oliveri Giulia D'Acunto Martijn. J.H. van Oort Akshay Phagu Ibtihal Al Amri Brian O. Bingen Valeria Paradies Gianluca Mincione Bimmer E. Claessen Aukelien C. Dimitriu‐Leen Joelle Kefer Hany Girgis Tessel Vossenberg Frank Van der Kley J. Wouter Jukema Josè M. Montero‐Cabezas Catheterization and Cardiovascular Interventions ABSTRACT Background Intravascular lithotripsy (IVL) has emerged as a promising treatment for heavily calcified coronary lesions. However, evidence regarding its effectiveness in calcific bifurcation lesions remains limited. Objective We aimed to evaluate the technical success and 1‐year clinical outcomes of IVL in calcified coronary bifurcation lesions. Methods Patients undergoing PCI with the use of IVL from the ongoing prospective BENELUX‐IVL registry were included. Participants were stratified into bifurcation and non‐bifurcation groups. The primary technical endpoint was technical success, defined as successful crossing of the IVL catheter across the target lesion with a residual stenosis of < 30%. The primary safety endpoint was in‐hospital major adverse cardiac events (MACE). Results Among 509 patients, 114 (22.4%) had coronary bifurcation lesions. Compared to the non‐bifurcation group, the bifurcation group had higher SYNTAX scores (25 [18–33] vs. 18 [10–29]; p < 0.01), longer procedural times (100 [75–129] min vs. 78 [59–107] min; p < 0.01), and greater contrast volume use (208 ± 8 mL vs. 176 ± 4 mL; p < 0.01). Abrupt side branch occlusion (1.8%) and bail‐out two‐stent techniques (3.6%) were infrequent. IVL achieved comparable technical success (91.2% vs. 90.0%, p = 0.71) and 1‐year MACE rates (9.6% vs. 5.8%, p = 0.20) in bifurcation versus non‐bifurcation lesions. Conclusion IVL demonstrates excellent safety and efficacy in calcified coronary bifurcation PCI, achieving high technical success with low device‐dependent adverse event rates. 10.1002/ccd.31713 http://creativecommons.org/licenses/by-nc/4.0/