Key Insights on the Classification and Theranostic Applications of Magnetic Resonance Imaging Contrast Agents
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Wiley Open Access
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| Format: | Artículo Open Access |
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Wiley
2024
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| _version_ | 1867016835827761152 |
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| author | Jasleen Kaur Manasvini Sridharr |
| author_facet | Jasleen Kaur Manasvini Sridharr Jasleen Kaur Manasvini Sridharr |
| collection | Wiley Open Access |
| contents | Key Insights on the Classification and Theranostic Applications of Magnetic Resonance Imaging Contrast Agents Jasleen Kaur Manasvini Sridharr ChemMedChem AbstractMagnetic resonance imaging (MRI) is a non‐invasive molecular imaging tool being extensively employed in clinical and biomedical research for the detection of a broad spectrum of diseases. This technique offers remarkable spatial resolution, good tissue penetration and a high soft tissue contrast. Contrast agents (CAs) have been regularly used in MRI tests to enhance the resolution of MR images and to visualize the diseased sites in the body. In the past years, considerable efforts have been devoted towards developing new theranostic MRI agents that can be tailored to integrate the targeting and therapeutic functions in a single agent. In this review, we have underlined the role of the MRI CAs in the developing field of ‘theranostics’ and their recent applications in the combined imaging and therapy of different types of tumors. In addition, this review also outlines the different categories of MRI CAs and their comprehensive classification based on different criteria such as chemical composition, relaxation mechanism and biodistribution with clinically relevant examples. 10.1002/cmdc.202300521 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1002/cmdc.202300521 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_cmdc_202300521 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Key Insights on the Classification and Theranostic Applications of Magnetic Resonance Imaging Contrast Agents Jasleen Kaur Manasvini Sridharr ChemMedChem Key Insights on the Classification and Theranostic Applications of Magnetic Resonance Imaging Contrast Agents Jasleen Kaur Manasvini Sridharr ChemMedChem AbstractMagnetic resonance imaging (MRI) is a non‐invasive molecular imaging tool being extensively employed in clinical and biomedical research for the detection of a broad spectrum of diseases. This technique offers remarkable spatial resolution, good tissue penetration and a high soft tissue contrast. Contrast agents (CAs) have been regularly used in MRI tests to enhance the resolution of MR images and to visualize the diseased sites in the body. In the past years, considerable efforts have been devoted towards developing new theranostic MRI agents that can be tailored to integrate the targeting and therapeutic functions in a single agent. In this review, we have underlined the role of the MRI CAs in the developing field of ‘theranostics’ and their recent applications in the combined imaging and therapy of different types of tumors. In addition, this review also outlines the different categories of MRI CAs and their comprehensive classification based on different criteria such as chemical composition, relaxation mechanism and biodistribution with clinically relevant examples. 10.1002/cmdc.202300521 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Key Insights on the Classification and Theranostic Applications of Magnetic Resonance Imaging Contrast Agents |
| topic | ChemMedChem |
| url | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202300521 |