Virtual Reality Body Exposure and Attentional Bias Modification in the Treatment of Adolescents With Anorexia Nervosa

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Main Authors: Mariarca Ascione, Marta Carulla‐Roig, Franck‐Alexandre Meschberger‐Annweiler, Eduardo Serrano‐Troncoso, Anna Blasco‐Martínez, Fernando Guerrero‐Álvarez, Helena Miquel‐Nabau, María Teresa Mendoza‐Medialdea, Bruno Porras‐Garcia, Marta Ferrer‐Garcia, Manuel Moreno‐Sánchez, José Gutierrez‐Maldonado
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Published: Wiley 2026
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author Mariarca Ascione
Marta Carulla‐Roig
Franck‐Alexandre Meschberger‐Annweiler
Eduardo Serrano‐Troncoso
Anna Blasco‐Martínez
Fernando Guerrero‐Álvarez
Helena Miquel‐Nabau
María Teresa Mendoza‐Medialdea
Bruno Porras‐Garcia
Marta Ferrer‐Garcia
Manuel Moreno‐Sánchez
José Gutierrez‐Maldonado
author_facet Mariarca Ascione
Marta Carulla‐Roig
Franck‐Alexandre Meschberger‐Annweiler
Eduardo Serrano‐Troncoso
Anna Blasco‐Martínez
Fernando Guerrero‐Álvarez
Helena Miquel‐Nabau
María Teresa Mendoza‐Medialdea
Bruno Porras‐Garcia
Marta Ferrer‐Garcia
Manuel Moreno‐Sánchez
José Gutierrez‐Maldonado
Mariarca Ascione
Marta Carulla‐Roig
Franck‐Alexandre Meschberger‐Annweiler
Eduardo Serrano‐Troncoso
Anna Blasco‐Martínez
Fernando Guerrero‐Álvarez
Helena Miquel‐Nabau
María Teresa Mendoza‐Medialdea
Bruno Porras‐Garcia
Marta Ferrer‐Garcia
Manuel Moreno‐Sánchez
José Gutierrez‐Maldonado
collection Wiley Open Access
contents Virtual Reality Body Exposure and Attentional Bias Modification in the Treatment of Adolescents With Anorexia Nervosa Mariarca Ascione Marta Carulla‐Roig Franck‐Alexandre Meschberger‐Annweiler Eduardo Serrano‐Troncoso Anna Blasco‐Martínez Fernando Guerrero‐Álvarez Helena Miquel‐Nabau María Teresa Mendoza‐Medialdea Bruno Porras‐Garcia Marta Ferrer‐Garcia Manuel Moreno‐Sánchez José Gutierrez‐Maldonado Clinical Psychology & Psychotherapy ABSTRACT Anorexia nervosa (AN) is a severe psychiatric disorder characterized by intense fear of gaining weight and persistent body image disturbance. Virtual reality–based mirror exposure therapy (VR‐MET) may reduce body‐related fear through embodied exposure, while attentional bias modification training (ABMT) may enhance exposure learning by promoting balanced attentional allocation. This controlled clinical study tested the hypothesis that adjunctive VR‐MET would improve clinical outcomes beyond treatment as usual (TAU) alone, and that preceding VR‐MET with ABMT would produce additional benefits in adolescent females with AN. Seventy‐five female adolescents with AN were allocated to TAU, TAU+VR‐MET or TAU+ABMT+VR‐MET. Assessments were conducted pre‐ and post‐intervention. Outcomes included eye‐tracking indices of attentional bias (number of fixations, complete fixation time), state anxiety and fear of gaining weight, BMI and eating disorder–related measures. Compared with TAU alone, both VR‐based conditions showed greater reductions in state anxiety and fear of gaining weight. State body dissatisfaction decreased significantly only in the TAU+VR‐MET group. No significant changes were observed for BMI or most trait‐level eating disorder measures. ABMT did not enhance clinical outcomes beyond VR‐MET. Within the short‐term assessment window, adjunctive VR‐MET was associated with reductions in state‐dependent emotional responses in adolescents with AN. Effects on trait‐level symptoms were limited, and ABMT did not confer additional benefit in this unselected sample. Fully randomized studies with larger samples, extended exposure protocols, and follow‐up assessments are needed to determine durability and broader clinical impact. 10.1002/cpp.70273 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1002/cpp.70273
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id wiley_oa_10_1002_cpp_70273
institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2026
publisher Wiley
record_format wiley_oa
spellingShingle Virtual Reality Body Exposure and Attentional Bias Modification in the Treatment of Adolescents With Anorexia Nervosa
Mariarca Ascione
Marta Carulla‐Roig
Franck‐Alexandre Meschberger‐Annweiler
Eduardo Serrano‐Troncoso
Anna Blasco‐Martínez
Fernando Guerrero‐Álvarez
Helena Miquel‐Nabau
María Teresa Mendoza‐Medialdea
Bruno Porras‐Garcia
Marta Ferrer‐Garcia
Manuel Moreno‐Sánchez
José Gutierrez‐Maldonado
Clinical Psychology & Psychotherapy
Virtual Reality Body Exposure and Attentional Bias Modification in the Treatment of Adolescents With Anorexia Nervosa Mariarca Ascione Marta Carulla‐Roig Franck‐Alexandre Meschberger‐Annweiler Eduardo Serrano‐Troncoso Anna Blasco‐Martínez Fernando Guerrero‐Álvarez Helena Miquel‐Nabau María Teresa Mendoza‐Medialdea Bruno Porras‐Garcia Marta Ferrer‐Garcia Manuel Moreno‐Sánchez José Gutierrez‐Maldonado Clinical Psychology & Psychotherapy ABSTRACT Anorexia nervosa (AN) is a severe psychiatric disorder characterized by intense fear of gaining weight and persistent body image disturbance. Virtual reality–based mirror exposure therapy (VR‐MET) may reduce body‐related fear through embodied exposure, while attentional bias modification training (ABMT) may enhance exposure learning by promoting balanced attentional allocation. This controlled clinical study tested the hypothesis that adjunctive VR‐MET would improve clinical outcomes beyond treatment as usual (TAU) alone, and that preceding VR‐MET with ABMT would produce additional benefits in adolescent females with AN. Seventy‐five female adolescents with AN were allocated to TAU, TAU+VR‐MET or TAU+ABMT+VR‐MET. Assessments were conducted pre‐ and post‐intervention. Outcomes included eye‐tracking indices of attentional bias (number of fixations, complete fixation time), state anxiety and fear of gaining weight, BMI and eating disorder–related measures. Compared with TAU alone, both VR‐based conditions showed greater reductions in state anxiety and fear of gaining weight. State body dissatisfaction decreased significantly only in the TAU+VR‐MET group. No significant changes were observed for BMI or most trait‐level eating disorder measures. ABMT did not enhance clinical outcomes beyond VR‐MET. Within the short‐term assessment window, adjunctive VR‐MET was associated with reductions in state‐dependent emotional responses in adolescents with AN. Effects on trait‐level symptoms were limited, and ABMT did not confer additional benefit in this unselected sample. Fully randomized studies with larger samples, extended exposure protocols, and follow‐up assessments are needed to determine durability and broader clinical impact. 10.1002/cpp.70273 http://creativecommons.org/licenses/by/4.0/
title Virtual Reality Body Exposure and Attentional Bias Modification in the Treatment of Adolescents With Anorexia Nervosa
topic Clinical Psychology & Psychotherapy
url https://onlinelibrary.wiley.com/doi/10.1002/cpp.70273