Copertina

Using Machine Learning to Individualize Treatment Effect Estimation: Challenges and Opportunities

Fuente: Wiley Open Access

Salvato in:

Dettagli Bibliografici
Autori principali:	Alicia Curth, Richard W. Peck, Eoin McKinney, James Weatherall, Mihaela van der Schaar
Natura:	Artículo Open Access
Pubblicazione:	Wiley 2024
Soggetti:	Clinical Pharmacology & Therapeutics
Accesso online:	Acceder al recurso
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi

Beyond Population‐Level Targets for Drug Concentrations: Precision Dosing Needs Individual‐Level Targets that Include Superior Biomarkers of Drug Responses
di: Thomas M. Polasek, et al.
Pubblicazione: (2024)

From Challenge to Opportunity: How Shwachman–Diamond Syndrome Became a Promising Target for Therapy Development
di: Eszter S. Hars, et al.
Pubblicazione: (2024)

Interchanging Biosimilars Using Proteomics
di: Piet H. van der Graaf, et al.
Pubblicazione: (2025)

Artificial Intelligence/Machine Learning: The New Frontier of Clinical Pharmacology and Precision Medicine
di: Qi Liu, et al.
Pubblicazione: (2024)

Harmonizing HTA Evidence Needs and Expectations: Challenges and Opportunities to Improve Evidence Generation, Ensure Access and Affordability
di: Sarah K. Emond, et al.
Pubblicazione: (2025)

Machine Learning for Prediction of Drug Concentrations: Application and Challenges
di: Shuqi Huang, et al.
Pubblicazione: (2025)

Using Machine Learning to Determine a Suitable Patient Population for Anakinra for the Treatment of COVID‐19 Under the Emergency Use Authorization
di: Qi Liu, et al.
Pubblicazione: (2024)

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes
di: Namam Ali, et al.
Pubblicazione: (2025)

Effects of GLPG3970 on Sulfasalazine and Methotrexate Pharmacokinetics in Healthy Adults: Two Open‐Label, Phase I, Drug–Drug Interaction Studies
di: Mariska van der Plas, et al.
Pubblicazione: (2024)

Progress in Clinical Pharmacology in China: An Ongoing Evolution
di: Liang Zhao, et al.
Pubblicazione: (2025)

Weaning off ThoroughQTStudies
di: Mai Mehanna, et al.
Pubblicazione: (2024)

History and Evolution of Innovations in Clinical Pharmacology
di: Lawrence J. Lesko, et al.
Pubblicazione: (2025)

Best Practices for Pharmacokinetic Studies of New Chemical Entities
di: Ya‐Feng Wen, et al.
Pubblicazione: (2024)

Reflections on Model‐Informed Drug Development
di: Lawrence J. Lesko, et al.
Pubblicazione: (2024)

Model‐Informed Precision Dosing Using Machine Learning for Levothyroxine in General Practice: Development, Validation and Clinical Simulation Trial
di: Jules M. Janssen Daalen, et al.
Pubblicazione: (2024)

Challenges and Possible Strategies to Address Them in Rare Disease Drug Development: A Statistical Perspective
di: Jie Chen, et al.
Pubblicazione: (2025)

Progress in Clinical Pharmacology in China: A Randomized Controlled Study to Advance Genotype‐Guided Precision Medicine
di: Liang Zhao, et al.
Pubblicazione: (2024)

Predicting Survival in Patients with Advanced NSCLC Treated with Atezolizumab Using Pre‐ and on‐Treatment Prognostic Biomarkers
di: Sébastien Benzekry, et al.
Pubblicazione: (2024)

Effect of Dapagliflozin on Measured vs. Panel‐Estimated Glomerular Filtration Rate
di: Esben Iversen, et al.
Pubblicazione: (2024)

The Drug Titration Paradox Updated and Reinterpreted: With Perfect Titration, Dose and Effect Will Be Uncorrelated
di: Elie Sarraf, et al.
Pubblicazione: (2025)

Algorithmic Identification of Treatment‐Emergent Adverse Events From Clinical Notes Using Large Language Models: A Pilot Study in Inflammatory Bowel Disease
di: Anna L. Silverman, et al.
Pubblicazione: (2024)

Challenging the Detection of Comedication Interactions Related to Immune‐Related Adverse Events Using Spontaneous Reporting Systems
di: Yuki Nakano
Pubblicazione: (2025)

Getting the Dosage Right: A Vital Role for Clinical Pharmacology in the Era of Precision Medicine
di: Iris K. Minichmayr, et al.
Pubblicazione: (2024)

Machine Learning‐Based Prediction of Escitalopram and Sertraline Side Effects With Pharmacokinetic Data in Children and Adolescents
di: Ethan A. Poweleit, et al.
Pubblicazione: (2024)

Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment
di: Nikki de Rouw, et al.
Pubblicazione: (2025)

Establishing a Validation Framework of Treatment Discontinuation in Claims Data Using Natural Language Processing and Electronic Health Records
di: Chun‐Ting Yang, et al.
Pubblicazione: (2025)

Pharmacotherapy to Improve Cognitive Functioning After Acquired Brain Injury: A Meta‐Analysis and Meta‐Regression
di: Ruud van der Veen, et al.
Pubblicazione: (2024)

Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers
di: Marella Cornelia Elizabeth van Ruissen, et al.
Pubblicazione: (2025)

Exploring the Association Between Intra‐Patient Variability in Trough Concentration of Pazopanib and Clinical Outcomes in Renal Cell Carcinoma and Soft Tissue Sarcoma Patients
di: Amy Rieborn, et al.
Pubblicazione: (2025)

Prevalence Estimates of Cytochrome P450 Phenoconversion in Youth Receiving Pharmacotherapy for Mental Health Conditions
di: Samuel Gerlach, et al.
Pubblicazione: (2024)

A Randomized Trial Comparing Standard of Care to Bayesian Warfarin Dose Individualization
di: Ling Xue, et al.
Pubblicazione: (2024)

Innovations in Clinical Pharmacology: Shaping the Future of Evidence Generation in Research, Development, and Utilization of Medicines
di: Karthik Venkatakrishnan, et al.
Pubblicazione: (2025)

Urinary Kidney Injury Biomarker Profiles in Healthy Individuals and After Nephrotoxic and Ischemic Injury
di: Sushrut S. Waikar, et al.
Pubblicazione: (2025)

Evaluating the Effect of Estimating Renal Function With the CKD‐EPI 2021 Equation on the ABCD‐GENE Score for Clopidogrel Response Prediction
di: Maryam Jamal AlSaeed, et al.
Pubblicazione: (2024)

Correction to “Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single‐Patient Data Meta‐Analysis in More Than 15,000 Individuals”
Pubblicazione: (2024)

A Comment about AI Methods that May Help Advance Pharmacovigilance
di: McKenna K. Anderson, et al.
Pubblicazione: (2026)

Moving the Needle for Oncology Dose Optimization: A Call for Action
di: Karthik Venkatakrishnan, et al.
Pubblicazione: (2024)

Machine Learning Prediction of Unbound Ceftriaxone Concentrations in Children: Capturing Developmental Changes in Protein Binding for Precision Dosing
di: Bo‐Hao Tang, et al.
Pubblicazione: (2026)

Dose Selection for DuoBody®‐CD40x4‐1BB (GEN1042/BNT312) Using a mPBPK/RO Model Leveraging Preclinical and Clinical Data
di: Gaurav Bajaj, et al.
Pubblicazione: (2025)

Model‐Based Patient Selection and Dosing Strategies for HRAS and PIK3CA Dysregulated HNSCC : A QSP Model for Alpelisib and Tipifarnib Combination
di: Jaehee Shim, et al.
Pubblicazione: (2026)