Chinese Expert Consensus on the Clinical Diagnosis and Management of Statin Intolerance
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Wiley
2024
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| author | Jian‐Jun Li Ke‐Fei Dou Zhi‐Guang Zhou Dong Zhao Ping Ye Hong Chen Zhen‐Yue Chen Dao‐Quan Peng Yuan‐Lin Guo Na‐Qiong Wu Jie Qian |
| author_facet | Jian‐Jun Li Ke‐Fei Dou Zhi‐Guang Zhou Dong Zhao Ping Ye Hong Chen Zhen‐Yue Chen Dao‐Quan Peng Yuan‐Lin Guo Na‐Qiong Wu Jie Qian Jian‐Jun Li Ke‐Fei Dou Zhi‐Guang Zhou Dong Zhao Ping Ye Hong Chen Zhen‐Yue Chen Dao‐Quan Peng Yuan‐Lin Guo Na‐Qiong Wu Jie Qian |
| collection | Wiley Open Access |
| contents | Chinese Expert Consensus on the Clinical Diagnosis and Management of Statin Intolerance Jian‐Jun Li Ke‐Fei Dou Zhi‐Guang Zhou Dong Zhao Ping Ye Hong Chen Zhen‐Yue Chen Dao‐Quan Peng Yuan‐Lin Guo Na‐Qiong Wu Jie Qian Clinical Pharmacology & Therapeutics The clinical benefits of statins have well‐established and recognized worldwide. Although statins are well‐tolerated generally, however, the report of statin‐related adverse event and statin intolerance are common in China, which results in insufficient use of statins and poor adherence. The main reason may be attributed to confusions or misconceptions in the clinical diagnosis and management in China, including the lack of unified definitions and diagnostic standards, broad grasp of diagnosis, and unscientific management strategies. Based on that, this consensus carefully summarized the statin‐related gene polymorphism and statin usage issue among Chinese population, and comprehensively reviewed global research data on statin intolerance, referenced guidelines, and consensus literature on statin intolerance in foreign and different regions, proposes an appropriate and easy to implement statin intolerance definition as well as corresponding diagnostic criteria and management strategies for Chinese clinicians, in order to improve the clinical application of statin drugs and enhance the prevention and treatment level of atherosclerotic cardiovascular disease in China. 10.1002/cpt.3213 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1002/cpt.3213 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_cpt_3213 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Chinese Expert Consensus on the Clinical Diagnosis and Management of Statin Intolerance Jian‐Jun Li Ke‐Fei Dou Zhi‐Guang Zhou Dong Zhao Ping Ye Hong Chen Zhen‐Yue Chen Dao‐Quan Peng Yuan‐Lin Guo Na‐Qiong Wu Jie Qian Clinical Pharmacology & Therapeutics Chinese Expert Consensus on the Clinical Diagnosis and Management of Statin Intolerance Jian‐Jun Li Ke‐Fei Dou Zhi‐Guang Zhou Dong Zhao Ping Ye Hong Chen Zhen‐Yue Chen Dao‐Quan Peng Yuan‐Lin Guo Na‐Qiong Wu Jie Qian Clinical Pharmacology & Therapeutics The clinical benefits of statins have well‐established and recognized worldwide. Although statins are well‐tolerated generally, however, the report of statin‐related adverse event and statin intolerance are common in China, which results in insufficient use of statins and poor adherence. The main reason may be attributed to confusions or misconceptions in the clinical diagnosis and management in China, including the lack of unified definitions and diagnostic standards, broad grasp of diagnosis, and unscientific management strategies. Based on that, this consensus carefully summarized the statin‐related gene polymorphism and statin usage issue among Chinese population, and comprehensively reviewed global research data on statin intolerance, referenced guidelines, and consensus literature on statin intolerance in foreign and different regions, proposes an appropriate and easy to implement statin intolerance definition as well as corresponding diagnostic criteria and management strategies for Chinese clinicians, in order to improve the clinical application of statin drugs and enhance the prevention and treatment level of atherosclerotic cardiovascular disease in China. 10.1002/cpt.3213 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Chinese Expert Consensus on the Clinical Diagnosis and Management of Statin Intolerance |
| topic | Clinical Pharmacology & Therapeutics |
| url | https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt.3213 |