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Auteurs principaux: Junhao Huang, Marcus Klahn, Stephan Bartling, Anna Zimina, Nils Rockstroh, Norbert Steinfeldt, Tim Peppel, Jan‐Dierk Grunwaldt, Jennifer Strunk
Format: Artículo Open Access
Publié: Wiley 2025
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Accès en ligne:https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202500953
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author Junhao Huang
Marcus Klahn
Stephan Bartling
Anna Zimina
Nils Rockstroh
Norbert Steinfeldt
Tim Peppel
Jan‐Dierk Grunwaldt
Jennifer Strunk
author_facet Junhao Huang
Marcus Klahn
Stephan Bartling
Anna Zimina
Nils Rockstroh
Norbert Steinfeldt
Tim Peppel
Jan‐Dierk Grunwaldt
Jennifer Strunk
Junhao Huang
Marcus Klahn
Stephan Bartling
Anna Zimina
Nils Rockstroh
Norbert Steinfeldt
Tim Peppel
Jan‐Dierk Grunwaldt
Jennifer Strunk
collection Wiley Open Access
contents Atomically Dispersed Palladium Promoted Suzuki–Miyaura Cross Coupling Junhao Huang Marcus Klahn Stephan Bartling Anna Zimina Nils Rockstroh Norbert Steinfeldt Tim Peppel Jan‐Dierk Grunwaldt Jennifer Strunk ChemSusChem The palladium‐catalyzed Suzuki – Miyaura cross coupling reaction to forge carbon‐carbon bonds fundamentally changes the practice of organic synthesis. Herein an isolated palladium catalyst supported on polymeric carbon nitride (Pd/PCN) for efficient cross coupling of bromobenzene and phenylboronic acid at room temperature is reported. It is demonstrated that the Pd/PCN catalyst with a 2 wt% Pd loading achieves the highest mole‐specific activity. In addition, the size of supported Pd can strongly affect the reaction performance: the isolated Pd species exhibit higher activity compared to the Pd nanoparticles. The continuous flow tests demonstrate that the catalytic properties of the Pd/PCN catalyst strongly depend on the reaction atmosphere: Pd‐catalyzed self‐coupling of phenylboronic acid as a side reaction is more pronounced under an O 2 flow than in an Ar flow. Detailed mechanistic investigations through in situ infrared spectroscopy reveal the role of the base K 2 CO 3 in activating the phenylboronic acid. 10.1002/cssc.202500953 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1002/cssc.202500953
format Artículo Open Access
id wiley_oa_10_1002_cssc_202500953
institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2025
publisher Wiley
record_format wiley_oa
spellingShingle Atomically Dispersed Palladium Promoted Suzuki–Miyaura Cross Coupling
Junhao Huang
Marcus Klahn
Stephan Bartling
Anna Zimina
Nils Rockstroh
Norbert Steinfeldt
Tim Peppel
Jan‐Dierk Grunwaldt
Jennifer Strunk
ChemSusChem
Atomically Dispersed Palladium Promoted Suzuki–Miyaura Cross Coupling Junhao Huang Marcus Klahn Stephan Bartling Anna Zimina Nils Rockstroh Norbert Steinfeldt Tim Peppel Jan‐Dierk Grunwaldt Jennifer Strunk ChemSusChem The palladium‐catalyzed Suzuki – Miyaura cross coupling reaction to forge carbon‐carbon bonds fundamentally changes the practice of organic synthesis. Herein an isolated palladium catalyst supported on polymeric carbon nitride (Pd/PCN) for efficient cross coupling of bromobenzene and phenylboronic acid at room temperature is reported. It is demonstrated that the Pd/PCN catalyst with a 2 wt% Pd loading achieves the highest mole‐specific activity. In addition, the size of supported Pd can strongly affect the reaction performance: the isolated Pd species exhibit higher activity compared to the Pd nanoparticles. The continuous flow tests demonstrate that the catalytic properties of the Pd/PCN catalyst strongly depend on the reaction atmosphere: Pd‐catalyzed self‐coupling of phenylboronic acid as a side reaction is more pronounced under an O 2 flow than in an Ar flow. Detailed mechanistic investigations through in situ infrared spectroscopy reveal the role of the base K 2 CO 3 in activating the phenylboronic acid. 10.1002/cssc.202500953 http://creativecommons.org/licenses/by/4.0/
title Atomically Dispersed Palladium Promoted Suzuki–Miyaura Cross Coupling
topic ChemSusChem
url https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202500953