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| Main Authors: | , , , , , , , , |
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| Format: | Artículo Open Access |
| Published: |
Wiley
2025
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| Subjects: | |
| Online Access: | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202500953 |
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Table of Contents:
- Atomically Dispersed Palladium Promoted Suzuki–Miyaura Cross Coupling Junhao Huang Marcus Klahn Stephan Bartling Anna Zimina Nils Rockstroh Norbert Steinfeldt Tim Peppel Jan‐Dierk Grunwaldt Jennifer Strunk ChemSusChem The palladium‐catalyzed Suzuki – Miyaura cross coupling reaction to forge carbon‐carbon bonds fundamentally changes the practice of organic synthesis. Herein an isolated palladium catalyst supported on polymeric carbon nitride (Pd/PCN) for efficient cross coupling of bromobenzene and phenylboronic acid at room temperature is reported. It is demonstrated that the Pd/PCN catalyst with a 2 wt% Pd loading achieves the highest mole‐specific activity. In addition, the size of supported Pd can strongly affect the reaction performance: the isolated Pd species exhibit higher activity compared to the Pd nanoparticles. The continuous flow tests demonstrate that the catalytic properties of the Pd/PCN catalyst strongly depend on the reaction atmosphere: Pd‐catalyzed self‐coupling of phenylboronic acid as a side reaction is more pronounced under an O 2 flow than in an Ar flow. Detailed mechanistic investigations through in situ infrared spectroscopy reveal the role of the base K 2 CO 3 in activating the phenylboronic acid. 10.1002/cssc.202500953 http://creativecommons.org/licenses/by/4.0/