Quality not quantity: Deficient juvenile play experiences lead to altered medial prefrontal cortex neurons and sociocognitive skill deficits
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Wiley
2024
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| author | Jackson R. Ham Madeline Szabo Jessica Annor‐Bediako Rachel A. Stark Andrew N. Iwaniuk Sergio M. Pellis |
| author_facet | Jackson R. Ham Madeline Szabo Jessica Annor‐Bediako Rachel A. Stark Andrew N. Iwaniuk Sergio M. Pellis Jackson R. Ham Madeline Szabo Jessica Annor‐Bediako Rachel A. Stark Andrew N. Iwaniuk Sergio M. Pellis |
| collection | Wiley Open Access |
| contents | Quality not quantity: Deficient juvenile play experiences lead to altered medial prefrontal cortex neurons and sociocognitive skill deficits Jackson R. Ham Madeline Szabo Jessica Annor‐Bediako Rachel A. Stark Andrew N. Iwaniuk Sergio M. Pellis Developmental Psychobiology AbstractReduced play experience over the juvenile period leads to adults with impoverished social skills and to anatomical and physiological aberrations of the neurons found in the medial prefrontal cortex (mPFC). Even rearing rats from high‐playing strains with low‐playing strains show these developmental consequences. In the present study, we evaluated whether low‐playing rats benefit from being reared with higher playing peers. To test this, we reared male Fischer 344 rats (F344), typically thought to be a low‐playing strain, with a Long–Evans (LE) peer, a relatively high‐playing strain. As juveniles, F344 rats reared with LE rats experienced less play and lower quality play compared to those reared with another F344. As adults, the F344 rats reared with LE partners exhibited poorer social skills and the pyramidal neurons of their mPFC had larger dendritic arbors than F344 rats reared with same‐strain peers. These findings show that being reared with a more playful partner does not improve developmental outcomes of F344 rats, rather the discordance in the play styles of F344 and LE rats leads to poorer outcomes. 10.1002/dev.22456 http://creativecommons.org/licenses/by-nc/4.0/ |
| doi_str_mv | 10.1002/dev.22456 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_dev_22456 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by-nc/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Quality not quantity: Deficient juvenile play experiences lead to altered medial prefrontal cortex neurons and sociocognitive skill deficits Jackson R. Ham Madeline Szabo Jessica Annor‐Bediako Rachel A. Stark Andrew N. Iwaniuk Sergio M. Pellis Developmental Psychobiology Quality not quantity: Deficient juvenile play experiences lead to altered medial prefrontal cortex neurons and sociocognitive skill deficits Jackson R. Ham Madeline Szabo Jessica Annor‐Bediako Rachel A. Stark Andrew N. Iwaniuk Sergio M. Pellis Developmental Psychobiology AbstractReduced play experience over the juvenile period leads to adults with impoverished social skills and to anatomical and physiological aberrations of the neurons found in the medial prefrontal cortex (mPFC). Even rearing rats from high‐playing strains with low‐playing strains show these developmental consequences. In the present study, we evaluated whether low‐playing rats benefit from being reared with higher playing peers. To test this, we reared male Fischer 344 rats (F344), typically thought to be a low‐playing strain, with a Long–Evans (LE) peer, a relatively high‐playing strain. As juveniles, F344 rats reared with LE rats experienced less play and lower quality play compared to those reared with another F344. As adults, the F344 rats reared with LE partners exhibited poorer social skills and the pyramidal neurons of their mPFC had larger dendritic arbors than F344 rats reared with same‐strain peers. These findings show that being reared with a more playful partner does not improve developmental outcomes of F344 rats, rather the discordance in the play styles of F344 and LE rats leads to poorer outcomes. 10.1002/dev.22456 http://creativecommons.org/licenses/by-nc/4.0/ |
| title | Quality not quantity: Deficient juvenile play experiences lead to altered medial prefrontal cortex neurons and sociocognitive skill deficits |
| topic | Developmental Psychobiology |
| url | https://onlinelibrary.wiley.com/doi/10.1002/dev.22456 |