Rapid seizure resolution with cannabidiol in medically refractory epilepsy with myoclonic‐atonic seizures
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Wiley Open Access
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| Format: | Artículo Open Access |
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Wiley
2024
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| _version_ | 1867011435235639296 |
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| author | Peter F. Sarnacki Elia Pestana‐Knight |
| author_facet | Peter F. Sarnacki Elia Pestana‐Knight Peter F. Sarnacki Elia Pestana‐Knight |
| collection | Wiley Open Access |
| contents | Rapid seizure resolution with cannabidiol in medically refractory epilepsy with myoclonic‐atonic seizures Peter F. Sarnacki Elia Pestana‐Knight Epileptic Disorders AbstractEpilepsy with myoclonic‐atonic seizures (EMAS) is an early childhood epilepsy syndrome with an explosive onset of multiple seizure types in a previously healthy child. EMAS often evolves to a drug‐resistant epileptic encephalopathy before a variable degree of remission around 3 years from onset. Highly purified cannabidiol (CBD, available in United States as Epidiolex®) has demonstrated efficacy and tolerability as an adjunct in medically refractory EMAS. We present two cases of medically refractory EMAS achieving rapid seizure freedom (7–30 days) with CBD, illustrating CBD as a potential effective monotherapy in EMAS. 10.1002/epd2.20321 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| doi_str_mv | 10.1002/epd2.20321 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_epd2_20321 |
| institution | Wiley Open Access |
| license_str_mv | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Rapid seizure resolution with cannabidiol in medically refractory epilepsy with myoclonic‐atonic seizures Peter F. Sarnacki Elia Pestana‐Knight Epileptic Disorders Rapid seizure resolution with cannabidiol in medically refractory epilepsy with myoclonic‐atonic seizures Peter F. Sarnacki Elia Pestana‐Knight Epileptic Disorders AbstractEpilepsy with myoclonic‐atonic seizures (EMAS) is an early childhood epilepsy syndrome with an explosive onset of multiple seizure types in a previously healthy child. EMAS often evolves to a drug‐resistant epileptic encephalopathy before a variable degree of remission around 3 years from onset. Highly purified cannabidiol (CBD, available in United States as Epidiolex®) has demonstrated efficacy and tolerability as an adjunct in medically refractory EMAS. We present two cases of medically refractory EMAS achieving rapid seizure freedom (7–30 days) with CBD, illustrating CBD as a potential effective monotherapy in EMAS. 10.1002/epd2.20321 http://onlinelibrary.wiley.com/termsAndConditions#vor |
| title | Rapid seizure resolution with cannabidiol in medically refractory epilepsy with myoclonic‐atonic seizures |
| topic | Epileptic Disorders |
| url | https://onlinelibrary.wiley.com/doi/10.1002/epd2.20321 |