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| Autori principali: | , , , , , , , |
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| Natura: | Artículo Open Access |
| Pubblicazione: |
Wiley
2025
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| Soggetti: | |
| Accesso online: | https://onlinelibrary.wiley.com/doi/10.1002/hed.70113 |
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Sommario:
- Myopericytoma of the Head and Neck: A Case Series and Literature Review Peter S. Giannaris Matthew Mendelsohn Mostafa Kokabee Shengjie Cui Dominick Guerrero Mark Chaskes Judd Fastenberg Charles C. L. Tong Head & Neck ABSTRACT Background Myopericytoma (MPC) is a rare perivascular tumor with myoid differentiation that poses diagnostic and therapeutic challenges in the head and neck. Methods We present four cases of oral and sinonasal MPC and conducted a literature review to analyze clinical characteristics, diagnostic approaches, and management. Results Sixty‐five published cases were identified, yielding a cohort of 69 patients. The oral cavity was the most common site (44.9%) followed by parotid (15.9%), sinonasal (10.1%), neck (10.1%), and other head regions (18.8%). Complete excision was achieved in 95.7% of cases with a 7.2% recurrence rate. Histopathology confirmed MPC in all cases with characteristic perivascular spindle cell proliferation, 95.6% showing positive smooth muscle actin immunostaining. Conclusion MPC must be considered in the differential diagnosis of vascular head and neck lesions. Complete surgical excision with negative margins remains the treatment of choice, with immunohistochemistry essential for accurate diagnosis. 10.1002/hed.70113 http://onlinelibrary.wiley.com/termsAndConditions#vor