The effect of cannabinoids on wound healing: A review

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Main Authors: Aniruddha C. Parikh, Christopher S. Jeffery, Zainab Sandhu, Benjamin P. Brownlee, Lurdes Queimado, Mark M. Mims
Format: Artículo Open Access
Published: Wiley 2024
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author Aniruddha C. Parikh
Christopher S. Jeffery
Zainab Sandhu
Benjamin P. Brownlee
Lurdes Queimado
Mark M. Mims
author_facet Aniruddha C. Parikh
Christopher S. Jeffery
Zainab Sandhu
Benjamin P. Brownlee
Lurdes Queimado
Mark M. Mims
Aniruddha C. Parikh
Christopher S. Jeffery
Zainab Sandhu
Benjamin P. Brownlee
Lurdes Queimado
Mark M. Mims
collection Wiley Open Access
contents The effect of cannabinoids on wound healing: A review Aniruddha C. Parikh Christopher S. Jeffery Zainab Sandhu Benjamin P. Brownlee Lurdes Queimado Mark M. Mims Health Science Reports AbstractBackground and AimsCannabis and its various derivatives are commonly used for both recreational and medicinal purposes. Cannabinoids have been shown to have anti‐inflammatory properties. Inflammation is an important component of wound healing and the effect of cannabinoids on wound healing has become a recent topic of investigation. The objective of this article is to perform a comprehensive review of the literature to summarize the effects of cannabinoids on wound healing of the skin and to guide future avenues of research.MethodsA comprehensive literature review was performed to evaluate the effects of cannabinoids on cutaneous wound healing.ResultsCannabinoids appear to improve skin wound healing through a variety of mechanisms. This is supported through a variety of in vitro and animal studies. Animal studies suggest application of cannabinoids may improve the healing of postsurgical and chronic wounds. There are few human studies which evaluate the effects of cannabinoids on wound healing and many of these are case series and observational studies. They do suggest cannabinoids may have some benefit. However, definitive conclusions cannot be drawn from them.ConclusionWhile further human studies are needed, topical application of cannabinoids may be a potential therapeutic option for postsurgical and chronic wounds. 10.1002/hsr2.1908 http://creativecommons.org/licenses/by/4.0/
doi_str_mv 10.1002/hsr2.1908
format Artículo Open Access
id wiley_oa_10_1002_hsr2_1908
institution Wiley Open Access
license_str_mv http://creativecommons.org/licenses/by/4.0/
publishDate 2024
publisher Wiley
record_format wiley_oa
spellingShingle The effect of cannabinoids on wound healing: A review
Aniruddha C. Parikh
Christopher S. Jeffery
Zainab Sandhu
Benjamin P. Brownlee
Lurdes Queimado
Mark M. Mims
Health Science Reports
The effect of cannabinoids on wound healing: A review Aniruddha C. Parikh Christopher S. Jeffery Zainab Sandhu Benjamin P. Brownlee Lurdes Queimado Mark M. Mims Health Science Reports AbstractBackground and AimsCannabis and its various derivatives are commonly used for both recreational and medicinal purposes. Cannabinoids have been shown to have anti‐inflammatory properties. Inflammation is an important component of wound healing and the effect of cannabinoids on wound healing has become a recent topic of investigation. The objective of this article is to perform a comprehensive review of the literature to summarize the effects of cannabinoids on wound healing of the skin and to guide future avenues of research.MethodsA comprehensive literature review was performed to evaluate the effects of cannabinoids on cutaneous wound healing.ResultsCannabinoids appear to improve skin wound healing through a variety of mechanisms. This is supported through a variety of in vitro and animal studies. Animal studies suggest application of cannabinoids may improve the healing of postsurgical and chronic wounds. There are few human studies which evaluate the effects of cannabinoids on wound healing and many of these are case series and observational studies. They do suggest cannabinoids may have some benefit. However, definitive conclusions cannot be drawn from them.ConclusionWhile further human studies are needed, topical application of cannabinoids may be a potential therapeutic option for postsurgical and chronic wounds. 10.1002/hsr2.1908 http://creativecommons.org/licenses/by/4.0/
title The effect of cannabinoids on wound healing: A review
topic Health Science Reports
url https://onlinelibrary.wiley.com/doi/10.1002/hsr2.1908