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Main Authors: Ruiming Zhu, Xinliang Liu, Yin Dai, Wei Qian, Yueyang Teng
Format: Artículo Open Access
Published: Wiley 2026
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Online Access:https://onlinelibrary.wiley.com/doi/10.1002/ima.70310
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author Ruiming Zhu
Xinliang Liu
Yin Dai
Wei Qian
Yueyang Teng
author_facet Ruiming Zhu
Xinliang Liu
Yin Dai
Wei Qian
Yueyang Teng
Ruiming Zhu
Xinliang Liu
Yin Dai
Wei Qian
Yueyang Teng
collection Wiley Open Access
contents Pearson Correlation Coefficient‐Guided Dynamic Supervision and Dual‐Attention Network for MR ‐to‐ CT Image Synthesis Ruiming Zhu Xinliang Liu Yin Dai Wei Qian Yueyang Teng International Journal of Imaging Systems and Technology ABSTRACT Accurate synthesis of computed tomography (CT) images from magnetic resonance (MR) scans is essential for reducing radiation exposure and enabling fully MR‐based workflows in clinical applications such as radiotherapy planning. To address this task, we propose a novel framework—Pearson correlation coefficient‐guided dual‐attention network (PDANet)—that integrates dynamic supervision and attention‐driven representation learning for MR‐to‐CT image synthesis. PDANet tackles two key limitations in existing methods: fixed loss weighting and insufficient feature modeling. First, a Pearson correlation coefficient‐guided dynamic supervision strategy is introduced to adaptively balance pixel‐wise and perceptual losses throughout training, which allows the model to emphasize perceptual consistency in early stages and gradually shift toward pixel‐level refinement as structural similarity improves. Second, a dual‐attention mechanism is incorporated into the generator to enhance long‐range dependency modeling and spatially aware feature representation, improving the synthesis of anatomical structures across varying scales. Experimental results on two publicly available datasets—pelvis and brain—demonstrate that PDANet consistently outperforms state‐of‐the‐art methods in terms of structural fidelity and visual quality, highlighting the robustness and generalizability of the approach across diverse anatomical regions. 10.1002/ima.70310 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/ima.70310
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institution Wiley Open Access
license_str_mv http://onlinelibrary.wiley.com/termsAndConditions#vor
publishDate 2026
publisher Wiley
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spellingShingle Pearson Correlation Coefficient‐Guided Dynamic Supervision and Dual‐Attention Network for MR ‐to‐ CT Image Synthesis
Ruiming Zhu
Xinliang Liu
Yin Dai
Wei Qian
Yueyang Teng
International Journal of Imaging Systems and Technology
Pearson Correlation Coefficient‐Guided Dynamic Supervision and Dual‐Attention Network for MR ‐to‐ CT Image Synthesis Ruiming Zhu Xinliang Liu Yin Dai Wei Qian Yueyang Teng International Journal of Imaging Systems and Technology ABSTRACT Accurate synthesis of computed tomography (CT) images from magnetic resonance (MR) scans is essential for reducing radiation exposure and enabling fully MR‐based workflows in clinical applications such as radiotherapy planning. To address this task, we propose a novel framework—Pearson correlation coefficient‐guided dual‐attention network (PDANet)—that integrates dynamic supervision and attention‐driven representation learning for MR‐to‐CT image synthesis. PDANet tackles two key limitations in existing methods: fixed loss weighting and insufficient feature modeling. First, a Pearson correlation coefficient‐guided dynamic supervision strategy is introduced to adaptively balance pixel‐wise and perceptual losses throughout training, which allows the model to emphasize perceptual consistency in early stages and gradually shift toward pixel‐level refinement as structural similarity improves. Second, a dual‐attention mechanism is incorporated into the generator to enhance long‐range dependency modeling and spatially aware feature representation, improving the synthesis of anatomical structures across varying scales. Experimental results on two publicly available datasets—pelvis and brain—demonstrate that PDANet consistently outperforms state‐of‐the‐art methods in terms of structural fidelity and visual quality, highlighting the robustness and generalizability of the approach across diverse anatomical regions. 10.1002/ima.70310 http://onlinelibrary.wiley.com/termsAndConditions#vor
title Pearson Correlation Coefficient‐Guided Dynamic Supervision and Dual‐Attention Network for MR ‐to‐ CT Image Synthesis
topic International Journal of Imaging Systems and Technology
url https://onlinelibrary.wiley.com/doi/10.1002/ima.70310