In vitro genotoxicological evaluation of protein‐rich powder derived from Xanthobacter sp. SoF1
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2024
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| author | Katharina Klinzing Ida Aabrandt Søndergaard Teresa Chirom James Whitwell Laura Bisini Cristina Marabottini Fabrice Nesslany Petri Tervasmäki Juha‐Pekka Pitkänen |
| author_facet | Katharina Klinzing Ida Aabrandt Søndergaard Teresa Chirom James Whitwell Laura Bisini Cristina Marabottini Fabrice Nesslany Petri Tervasmäki Juha‐Pekka Pitkänen Katharina Klinzing Ida Aabrandt Søndergaard Teresa Chirom James Whitwell Laura Bisini Cristina Marabottini Fabrice Nesslany Petri Tervasmäki Juha‐Pekka Pitkänen |
| collection | Wiley Open Access |
| contents | In vitro genotoxicological evaluation of protein‐rich powder derived from Xanthobacter sp. SoF1 Katharina Klinzing Ida Aabrandt Søndergaard Teresa Chirom James Whitwell Laura Bisini Cristina Marabottini Fabrice Nesslany Petri Tervasmäki Juha‐Pekka Pitkänen Journal of Applied Toxicology AbstractOne way of limiting the environmental impact of food production and improving food security is to replace part of the animal‐ or plant‐based protein in the human diet with protein sourced from microorganisms. The recently discovered bacterium Xanthobacter sp. SoF1 (VTT‐E‐193585) grows autotrophically using carbon dioxide gas as the only carbon source, yielding protein‐rich biomass that can be processed further into a powder and incorporated into various food products. Since the safety of this microbial protein powder for human consumption had not been previously assessed, its genotoxic potential was evaluated employing three internationally recognized and standardized studies: a bacterial reverse mutation test, an in vitro chromosomal aberration assay in human lymphocytes, and an in vitro micronucleus test in human lymphocytes. No biologically relevant evidence of genotoxicity or mutagenicity was found. 10.1002/jat.4621 http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| doi_str_mv | 10.1002/jat.4621 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_jat_4621 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | In vitro genotoxicological evaluation of protein‐rich powder derived from Xanthobacter sp. SoF1 Katharina Klinzing Ida Aabrandt Søndergaard Teresa Chirom James Whitwell Laura Bisini Cristina Marabottini Fabrice Nesslany Petri Tervasmäki Juha‐Pekka Pitkänen Journal of Applied Toxicology In vitro genotoxicological evaluation of protein‐rich powder derived from Xanthobacter sp. SoF1 Katharina Klinzing Ida Aabrandt Søndergaard Teresa Chirom James Whitwell Laura Bisini Cristina Marabottini Fabrice Nesslany Petri Tervasmäki Juha‐Pekka Pitkänen Journal of Applied Toxicology AbstractOne way of limiting the environmental impact of food production and improving food security is to replace part of the animal‐ or plant‐based protein in the human diet with protein sourced from microorganisms. The recently discovered bacterium Xanthobacter sp. SoF1 (VTT‐E‐193585) grows autotrophically using carbon dioxide gas as the only carbon source, yielding protein‐rich biomass that can be processed further into a powder and incorporated into various food products. Since the safety of this microbial protein powder for human consumption had not been previously assessed, its genotoxic potential was evaluated employing three internationally recognized and standardized studies: a bacterial reverse mutation test, an in vitro chromosomal aberration assay in human lymphocytes, and an in vitro micronucleus test in human lymphocytes. No biologically relevant evidence of genotoxicity or mutagenicity was found. 10.1002/jat.4621 http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| title | In vitro genotoxicological evaluation of protein‐rich powder derived from Xanthobacter sp. SoF1 |
| topic | Journal of Applied Toxicology |
| url | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.4621 |