Buchumschlag

Xylazine‐Adulterated Fentanyl‐Induced Brain Toxicity: Mechanism Elucidation via Network Toxicology and Molecular Docking Approaches

Fuente: Wiley Open Access

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Ning Wang, Yangchang Ou, Yihan Wang, Zhenqi Huang, Yubo Hu, Shuquan Zhao
Format:	Artículo Open Access
Veröffentlicht:	Wiley 2025
Schlagworte:	Journal of Applied Toxicology
Online-Zugang:	Acceder al recurso
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge

Revealing the Impact of Mono(2‐ethylhexyl) Phthalate (MEHP) on Prostate Cancer Based on Network Toxicology and Molecular Docking Approaches
von: Chenyu Liang, et al.
Veröffentlicht: (2025)

Neuroimmune Cross‐Talk and Multilevel Cascades in Fentanyl Toxicity: Interplay of Hypoxic Stress, Glial Activation, and Synaptic Dysregulation in Systems‐Level Neurodegeneration
von: Hamzeh J. Al‐Ameer, et al.
Veröffentlicht: (2026)

Exploring the Diagnostic Potential of Core Targets of 6PPD and Its Metabolite 6PPD‐Q in Cardiovascular Diseases: An Integrated Analysis Based on Network Toxicology, Molecular Docking, and In Vitro Validation
von: Bing Guo, et al.
Veröffentlicht: (2025)

Metabolomics‐Based Insights Into the Toxicological Effects and Mechanisms of Microplastics: A Comprehensive Review
von: Ziyue Wang, et al.
Veröffentlicht: (2026)

Comprehensive Review on the Toxicology of Neodymium Oxide and Pharmaceutical Applications
von: Ning Yang, et al.
Veröffentlicht: (2025)

Black Carbon, Oxidative Potential, and Zebrafish Toxicity: A Toxicological Study of PM 2.5 in Tennessee
von: Voke Tonia Aminone, et al.
Veröffentlicht: (2025)

Integrated Network Pharmacology and Experimental Study on Shikonin‐Induced Male Reproductive Toxicity
von: Ruirui Qian, et al.
Veröffentlicht: (2025)

Toxicological Impacts of Arecoline and Tobacco in Oral Submucous Fibrosis: Mechanisms and Therapeutic Insights
von: Devaraj Ezhilarasan, et al.
Veröffentlicht: (2025)

Lead and Cadmium Induced Toxicity Under Prolonged Low‐Dose Exposure: Food Chain Driven Source, Molecular Mechanisms, Signaling Cascade, and Health Implications
von: Saikat Mazumder, et al.
Veröffentlicht: (2026)

Mycotoxin Alternariol Induces Ca 2+ Dysregulation and Cell Death in Astrocytes: Mechanistic Toxicological Insights
von: Ying‐Tso Chen, et al.
Veröffentlicht: (2026)

Insects as Experimental Models to Study the Toxicological Effects of Nanoparticles: Concerns at the Behavioral, Physiological, Cellular, and Molecular Levels
von: Kumbalingam Monica, et al.
Veröffentlicht: (2025)

Association and Toxic Mechanism Between Foodborne OTA Exposure and Embryonic Development
von: Teng Yao, et al.
Veröffentlicht: (2026)

Development and Application of Organoids for Toxicology Studies
von: Peilin Han, et al.
Veröffentlicht: (2026)

Preclinical Evaluation of Protective Effects of Terpenoids Against Nanomaterial‐Induced Toxicity: A Meta‐Analysis
von: Yuexiao Sun, et al.
Veröffentlicht: (2024)

A Multimodal Approach to Identify Metallothionein Metal Inducers in Nile Tilapia: Insights From Molecular Docking and Hepatocyte Exposure
von: Jessica Zablocki da Luz, et al.
Veröffentlicht: (2025)

Exposure Risks of Trans‐Perfluoro (4‐Methyl‐2‐Pentene) Byproduct in C 6 F 12 O Fire Suppressants: Toxicological Mechanisms and Implications
von: Biao Zhou, et al.
Veröffentlicht: (2025)

Samarium Oxide Exposure Induces Toxicity and Cardiotoxicity in Zebrafish Embryos Through Apoptosis Pathway
von: Yan Liu, et al.
Veröffentlicht: (2025)

Review of Organophosphorus Herbicide: Distribution of Residues, Toxicity Effects, Mechanisms, and Developing Trends Studies
von: Weiwei Feng, et al.
Veröffentlicht: (2026)

Environmental Concentrations of Polystyrene Nanoplastics Induce Low‐Dose Tamoxifen Toxicity Through Oxidative Stress in Caenorhabditis elegans
von: Chenchen Wang, et al.
Veröffentlicht: (2025)

Toxicological Perspectives on RNA m1A Methylation: Biological Processes and Pathological Consequences
von: Jiaqi Fu, et al.
Veröffentlicht: (2025)

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management
von: Serkan Yilmaz, et al.
Veröffentlicht: (2026)

Evaluating Solvent Safety in Chromosome Aberration Assays for Genetic Toxicology
von: Satyam N. Patel, et al.
Veröffentlicht: (2025)

Toxicological and Immunological Evaluation of MXene Quantum Dots for Nanomedicine Applications
von: Ghada Al‐Assi, et al.
Veröffentlicht: (2026)

6‐Chloronicotinic Acid Induces Toxicity in Mouse Neural Stem Cells via the C3ar1 Signaling
von: Min He, et al.
Veröffentlicht: (2024)

Parental Exposure to Nanoplastics and Graphene Oxide Induces Transgenerational Toxicity in Caenorhabditis elegans
von: Gabriela Corrêa Soares, et al.
Veröffentlicht: (2026)

Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps
von: Caroline V. L. Moreira, et al.
Veröffentlicht: (2025)

Toxicological Assessment and Physiological Responses to Dichloro‐Octylisothiazolinone and Octylisothiazolinone in Zebrafish Larvae
von: Maria Giovanna Rizzo, et al.
Veröffentlicht: (2026)

Toxicology and safety study of L‐tryptophan and its impurities for use in swine
von: Ji‐Eun Park, et al.
Veröffentlicht: (2024)

Systems Toxicology of Bisphenol A: Mechanistic Overlap in Metabolic and Reproductive Disruption
von: Sweta Bhardwaj, et al.
Veröffentlicht: (2026)

Deciphering the Pathogenic Cascade of Acrolein‐Induced Lung Injury: From Molecular Insult to Organ Failure
von: Zhihua Zhu, et al.
Veröffentlicht: (2026)

Revealing the Risks: A Review on the Toxicity and Mechanisms of Biodegradable Microplastics in Terrestrial Mammals
von: Lingjie Wu, et al.
Veröffentlicht: (2026)

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids
von: Victor Ventura de Souza, et al.
Veröffentlicht: (2026)

Human Umbilical Vein Endothelial Cells (HUVECs) in Pharmacology and Toxicology: A Review
von: Yi Cao
Veröffentlicht: (2025)

Pilot Study of Acute and Subchronic Oral Toxicological Biosafety Evaluation of Resorcinol‐Formaldehyde Aerogel Nanomaterial in Kunming Mice
von: Guangzhen Zheng, et al.
Veröffentlicht: (2024)

Transgenerational Reproductive and Developmental Toxicity Induced by N‐Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster
von: Oscar Eduardo Tabares‐Mosquera, et al.
Veröffentlicht: (2025)

Impact of Oxidative Stress on Reproductive Toxicity Induced by Alpha‐Terpineol in Male Sprague–Dawley Rats
von: Pakkiresha Goravara, et al.
Veröffentlicht: (2025)

Involvement of the PI3K/Nrf2 Pathway in Arsenic‐Induced Endocrine and Thyroid Toxicity in Rats
von: Xiaowei Ma, et al.
Veröffentlicht: (2025)

A Novel Regulatory Network of Noncoding RNAs in the Cadmium‐Induced Malignant Transformation of Human Bronchial Epithelial Cells
von: Yueqing Shao, et al.
Veröffentlicht: (2025)

Biomphalaria alexandrina and Artemia salina as Bioindicators of Glyphosate‐Isopropyl Ammonium Herbicide Pollution: Biological, Physiological, and Molecular Docking Studies
von: Amina Mohamed Ibrahim, et al.
Veröffentlicht: (2025)

Assessing the Biosafety of Chitosan‐Based Nanohybrid Fertilizers: A Multitropic Toxicological Study for Sustainable Agriculture
von: Cheran Easwaran, et al.
Veröffentlicht: (2025)