Cover Image

Carvedilol Confers Neuroprotective Activity Through Modulating Ferroptosis Key Players and PINK1/PARKIN Mediated Mitophagy in an Experimental Parkinson's Rat Model

Fuente: Wiley Open Access

Saved in:

Bibliographic Details
Main Authors:	Nermeen Z. Abuelezz, Mariam K. Ahmed, Amira Emad Abd El Aziz, Nesrine S. El Sayed
Format:	Artículo Open Access
Published:	Wiley 2025
Subjects:	Journal of Biochemical and Molecular Toxicology
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Protection of Dipsacoside B Against Cerebral Ischemia/Reperfusion Injury via Activating PINK1/Parkin‐Mediated Mitophagy
by: Guozheng Sun, et al.
Published: (2025)

SALL4/ABCB6 Axis Suppresses Ferroptosis in Colon Cancer by Mediating Mitophagy
by: Leilei Yang, et al.
Published: (2025)

Adverse Effects of Furan on Fetal Development, Growth Plate Integrity, and Placental Functioning in Wistar Rats
by: Entsar R. Abd‐Allah, et al.
Published: (2025)

Daidzein Attenuates Cadmium‐Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague–Dawley Rats
by: Shuangquan Wen, et al.
Published: (2025)

Unraveling the Potential of Empagliflozin to Counteract 1,2‐Dimethylhydrazine‐Induced Colorectal Cancer in Rats: Involvement of Redox Imbalance, Inflammatory Cascades, and Unprogrammed Cell Proliferation
by: Hager Abd Al‐Hamid, et al.
Published: (2026)

Linagliptin Mitigates DMH‐Induced Colorectal Cancer in Rats: Crosstalk Between NFAT and IL‐6/JAK2/STAT3/NF‐κB Signaling Hubs
by: Mohamed O. Mahmoud, et al.
Published: (2025)

Synthesis and Biological Evaluation of Thiazolyl–Pyrimidine Hybrids as Potential Antiproliferative Agents With Molecular Docking Insights
by: Sobhi M. Gomha, et al.
Published: (2025)

Mechanism of Nano‐Microplastics Exposure‐Induced Myocardial Fibrosis: DKK3‐Mediated Mitophagy Dysfunction and Pyroptosis
by: Liang Xiong, et al.
Published: (2025)

Protective Effect of SESN2 on Glutamate Neurotoxicity via Keap1‐Nrf2 Pathway‐Mediated Mitophagy
by: Xiu‐Mei Zhang, et al.
Published: (2025)

Protective Effect of Saroglitazar Against Acute Lung Injury Induced by LPS in Rats
by: Marina R. Francis, et al.
Published: (2026)

Oxidative/Nitrosative Stress, Apoptosis, and Redox Signaling: Key Players in Neurodegenerative Diseases
by: Nuray Üremiş, et al.
Published: (2025)

RETRACTION: Vitamin D3 Exerts a Neuroprotective Effect in Metabolic Syndrome Rats: Role of BDNF/TRKB/Akt/GS3Kβ Pathway
Published: (2026)

Lycopene Ameliorates Polycystic Ovary Syndrome in Rats by Inhibiting Ovarian Ferroptosis Through Activation of the AMPK/Nrf2 Pathway
by: Kexin Wang, et al.
Published: (2025)

Antiproliferative Activity and Molecular Docking of Some Pyrazole‐Based Quinazolinone, Benzimidazole, and Tetrazinethione Derivatives
by: Sayed K. Ramadan, et al.
Published: (2025)

Anti‐Inflammatory Effect of Dopamine D2 Receptor Agonist Cabergoline Against L‐Arginine‐Induced Acute Pancreatitis in Rats
by: Randa A. Zaghloul, et al.
Published: (2025)

A Novel Nanocombination of Lactoferrin With Green Synthesized Zinc Oxide Nanoparticles for Alleviating Bleomycin‐Induced Oxidative Stress and Cardiotoxicity in Male Rats
by: Mahmoud Ashry, et al.
Published: (2025)

Evaluation of the Synergistic Hepatoprotective Action of Metformin and Taurine in a Rat Model of Liver Cirrhosis
by: Sherouk S. Badawy, et al.
Published: (2025)

Dexmedetomidine Blocks NCOA4‐Dependent Ferritinophagy to Confer Ferroptosis Resistance in Lung Ischemia Reperfusion Injury via Targeting NRF2
by: Li Qu, et al.
Published: (2025)

Carvedilol Upregulates Inflammatory Factors to Enhance Paclitaxel Sensitivity in Paclitaxel‐Resistant Gastric Cancer AGS Cells: Influences on β‐Arrestin‐2/cGAS‐STING Axis
by: Haleh Salati Momeni, et al.
Published: (2026)

Unraveling the Therapeutic Landscape of miRNAs in Kaposi Sarcoma
by: Heba Ibrahim Abd El‐Moaty, et al.
Published: (2026)

Hypoxia‐Inducible Factor‐1α Regulates BNIP3‐Dependent Mitophagy and Mediates Metabolic Reprogramming Through Histone Lysine Lactylation Modification to Affect Glioma Proliferation and Invasion
by: Feng Dong, et al.
Published: (2025)

The Mitigated Effect of the Combination of Metformin and Stearic Acid to Ameliorate Bleomycin‐Induced Pulmonary Fibrosis in Rats via Inhibiting Gal‐3/Smad3/α‐SMA and TNF‐α/NF‐κβ Signaling Pathways
by: Maha M. Salem, et al.
Published: (2025)

Short‐Chain Fatty Acids Modulate Iron Metabolism and Induce Oxidative Stress and Ferroptosis in Breast Cancer Cells
by: Bilal Rah, et al.
Published: (2026)

An Overview of Neuroprotective Effects of Erythropoietin Against Neurological Disorders: Beyond Erythropoiesis
by: Bharat Bhushan, et al.
Published: (2025)

Novel Triazolopyridine Derivatives: Synthesis, Antimicrobial, Anticancer Evaluation and Molecular Docking Studies
by: Amina A. Abd El‐Gwaad, et al.
Published: (2026)

Mercuric Chloride‐Mediated Neurotoxicity in Chicken Embryos: Disruption of the Blood–Brain Barrier Integrity and Iron Overload‐Induced Ferroptosis
by: Hong‐Yu Fu, et al.
Published: (2026)

N 7 ‐Methylguanine Modification of SHMT2 Mediated by GEMIN5 Inhibits Cell Ferroptosis of Colorectal Cancer Cells
by: Zhiquan Wang, et al.
Published: (2025)

Vinpocetine Alleviates Valproic Acid‐Induced Hepatotoxicity and Neurotoxicity Through Activation of cAMP and PI3K/AKT/CREB Pathway in Rats
by: Heba M. Hafez, et al.
Published: (2025)

Selenium Ameliorates Modafinil‐Induced Male Reproductive Toxicity via Modulation of PI3K/Akt/NF‐ҡB Pathway: Experimental Study and Molecular Docking Verification
by: Shaimaa A. Shehata, et al.
Published: (2025)

Involvement of IL‐6/JAK/STAT3/SOCS3, SIRT1, and Cytoglobin Signaling in Diacerein Protective Effect against Intestinal Injury Induced by Methotrexate
by: Gaber F. Ali, et al.
Published: (2025)

Remimazolam Inhibits Neuronal Apoptosis, Inflammation, and Ferroptosis in Cerebral Infarction via Promoting TRIM67‐Mediated Degradation of ACSL4
by: Gaopeng Xiao, et al.
Published: (2026)

Downregulation of CLEC2 Facilitates the Proliferation and Migration of Multiple Myeloma Cells via Regulating HIF‐1α‐Mediated Ferroptosis
by: Fangbing Zhu, et al.
Published: (2025)

RETRACTION: The Pyrethroid Insecticide Permethrin Confers Hepatotoxicity Through DNA Damage and Mitochondria‐Associated Apoptosis Induction in Rat: Palliative Benefits of Fumaria Officinalis
Published: (2025)

Dimethyl Fumarate Ameliorates Collagen‐Induced Arthritis in Lewis Rats by Modulation of Th17/Treg Balance
by: Ali Sheikhian, et al.
Published: (2025)

WTAP Interferes With Ferroptosis by Regulating the m6A Modification of SF3B1 to Mediate the Malignant Progression of Endometrial Cancer
by: Xia Wang, et al.
Published: (2026)

Crocin Ameliorates Testicular Damage in Type 1 Diabetic Rats: Role of Akt‐Mediated Nrf‐2 Activation
by: Gözdenur Güneş, et al.
Published: (2026)

Protective Effects of Quercetin Against Vincristine‐Induced Nephrotoxicity via Modulation of Oxidative Stress, Inflammation, and Apoptosis in Rats
by: Özge Kandemir, et al.
Published: (2025)

SIRT1 Mediated by Baicalein and GFI1 Promotes Osteogenic Differentiation and Ameliorates Osteoporosis by Inhibiting Ferroptosis in Bone Marrow Mesenchymal Stem Cells
by: Liwei Bai, et al.
Published: (2025)

HHLA3 Silencing Suppresses KRAS‐Mutant Non‐Small‐Cell Lung Cancer Cell Progression Through Triggering MYEOV‐Mediated Ferroptosis
by: Zhimiao Tang, et al.
Published: (2025)

ALOX15‐Mediated 15‐HETE Uptake Drives Lung Cancer Cells Ferroptosis and Enhances CD8+ T Cell Immunity in Lung Cancer
by: Jianglong Wang, et al.
Published: (2026)