A multi‐institutional survey of apheresis services among institutions in the United States
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Wiley Open Access
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| Format: | Artículo Open Access |
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Wiley
2024
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| author | Nalan Yurtsever Jeremy W. Jacobs Garrett S. Booth Joseph Schwartz Yara A. Park Jennifer S. Woo Deisen Lauro Sarina Torres Dawn C. Ward Laura D. Stephens Elizabeth S. Allen Christopher A. Tormey Brian D. Adkins |
| author_facet | Nalan Yurtsever Jeremy W. Jacobs Garrett S. Booth Joseph Schwartz Yara A. Park Jennifer S. Woo Deisen Lauro Sarina Torres Dawn C. Ward Laura D. Stephens Elizabeth S. Allen Christopher A. Tormey Brian D. Adkins Nalan Yurtsever Jeremy W. Jacobs Garrett S. Booth Joseph Schwartz Yara A. Park Jennifer S. Woo Deisen Lauro Sarina Torres Dawn C. Ward Laura D. Stephens Elizabeth S. Allen Christopher A. Tormey Brian D. Adkins |
| collection | Wiley Open Access |
| contents | A multi‐institutional survey of apheresis services among institutions in the United States Nalan Yurtsever Jeremy W. Jacobs Garrett S. Booth Joseph Schwartz Yara A. Park Jennifer S. Woo Deisen Lauro Sarina Torres Dawn C. Ward Laura D. Stephens Elizabeth S. Allen Christopher A. Tormey Brian D. Adkins Journal of Clinical Apheresis AbstractIntroductionApheresis practices in the United States (US) have not been comprehensively characterized to date. This study aimed to address this gap by evaluating apheresis therapy through a national survey.MethodsA multi‐institutional survey was conducted between April and July 2023. The survey, comprising 54 questions, focused on institutional demographics, procedures, equipment, staffing, training, and impacts of the Coronavirus Disease 2019 (COVID‐19) pandemic. Responses from 22 institutions, primarily academic medical centers, were analyzed.ResultsTherapeutic plasma exchange (TPE) was the most common procedure, followed by hematopoietic progenitor cell collection (HPC‐A) and red blood cell exchange (RCE). CAR‐T cell collections were widespread, with some institutions supporting over 30 protocols concurrently. Most sites used the Spectra Optia Apheresis System, were managed by a transfusion medicine service, and employed internal apheresis providers. Insufficient staffing levels, exacerbated by the COVID‐19 pandemic, were common and most often addressed using overtime.DiscussionThe survey highlighted the ubiquity of TPE, expanding cellular collections and staffing challenges. The role of apheresis in supporting cellular therapy, particularly in newly developing cell and gene therapies and clinical trials, was evident. Staffing issues during the pandemic emphasized the need for innovative recruitment strategies.ConclusionThis nationwide survey provides the most comprehensive analysis to date of apheresis practices in large US academic centers. 10.1002/jca.22138 http://creativecommons.org/licenses/by/4.0/ |
| doi_str_mv | 10.1002/jca.22138 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_jca_22138 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | A multi‐institutional survey of apheresis services among institutions in the United States Nalan Yurtsever Jeremy W. Jacobs Garrett S. Booth Joseph Schwartz Yara A. Park Jennifer S. Woo Deisen Lauro Sarina Torres Dawn C. Ward Laura D. Stephens Elizabeth S. Allen Christopher A. Tormey Brian D. Adkins Journal of Clinical Apheresis A multi‐institutional survey of apheresis services among institutions in the United States Nalan Yurtsever Jeremy W. Jacobs Garrett S. Booth Joseph Schwartz Yara A. Park Jennifer S. Woo Deisen Lauro Sarina Torres Dawn C. Ward Laura D. Stephens Elizabeth S. Allen Christopher A. Tormey Brian D. Adkins Journal of Clinical Apheresis AbstractIntroductionApheresis practices in the United States (US) have not been comprehensively characterized to date. This study aimed to address this gap by evaluating apheresis therapy through a national survey.MethodsA multi‐institutional survey was conducted between April and July 2023. The survey, comprising 54 questions, focused on institutional demographics, procedures, equipment, staffing, training, and impacts of the Coronavirus Disease 2019 (COVID‐19) pandemic. Responses from 22 institutions, primarily academic medical centers, were analyzed.ResultsTherapeutic plasma exchange (TPE) was the most common procedure, followed by hematopoietic progenitor cell collection (HPC‐A) and red blood cell exchange (RCE). CAR‐T cell collections were widespread, with some institutions supporting over 30 protocols concurrently. Most sites used the Spectra Optia Apheresis System, were managed by a transfusion medicine service, and employed internal apheresis providers. Insufficient staffing levels, exacerbated by the COVID‐19 pandemic, were common and most often addressed using overtime.DiscussionThe survey highlighted the ubiquity of TPE, expanding cellular collections and staffing challenges. The role of apheresis in supporting cellular therapy, particularly in newly developing cell and gene therapies and clinical trials, was evident. Staffing issues during the pandemic emphasized the need for innovative recruitment strategies.ConclusionThis nationwide survey provides the most comprehensive analysis to date of apheresis practices in large US academic centers. 10.1002/jca.22138 http://creativecommons.org/licenses/by/4.0/ |
| title | A multi‐institutional survey of apheresis services among institutions in the United States |
| topic | Journal of Clinical Apheresis |
| url | https://onlinelibrary.wiley.com/doi/10.1002/jca.22138 |