Small but mighty: Case report and practical guidance for peripheral blood stem cell collection in small infants
Fuente:
Wiley Open Access
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Format: | Artículo Open Access |
| Veröffentlicht: |
Wiley
2024
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1867005346446311424 |
|---|---|
| author | Hannah Walker Erin O'Reilly Zoe Millard Brendan Cusack Anna Duncan Luisa Clucas Jacqueline Fleming David Hughes Anthea Greenway David Metz |
| author_facet | Hannah Walker Erin O'Reilly Zoe Millard Brendan Cusack Anna Duncan Luisa Clucas Jacqueline Fleming David Hughes Anthea Greenway David Metz Hannah Walker Erin O'Reilly Zoe Millard Brendan Cusack Anna Duncan Luisa Clucas Jacqueline Fleming David Hughes Anthea Greenway David Metz |
| collection | Wiley Open Access |
| contents | Small but mighty: Case report and practical guidance for peripheral blood stem cell collection in small infants Hannah Walker Erin O'Reilly Zoe Millard Brendan Cusack Anna Duncan Luisa Clucas Jacqueline Fleming David Hughes Anthea Greenway David Metz Journal of Clinical Apheresis AbstractModern apheresis devices, with increased procedural precision, automation, and monitoring, have been shown to allow for safe delivery of apheresis therapies in young children. Medical advances are increasing demand for apheresis procedures like mononuclear cell collection in infants <10 kg, including stem‐cell supported chemotherapy, cell collection for chimeric antigen receptor T cell development, and now ex vivo gene therapies for rare genetic diseases. Nevertheless, safe delivery in small infants involves a range of unique considerations and challenges, beyond just size, and experience will vary between centers. In this case report we describe our experience performing mononuclear cell collection in our smallest patient to date and outline a practice guideline developed following a literature review and discussion with both international experts and device representatives. This case may help to inform other clinicians aiming to provide apheresis care to very small infants in their own centers. 10.1002/jca.22141 http://creativecommons.org/licenses/by-nc/4.0/ |
| doi_str_mv | 10.1002/jca.22141 |
| format | Artículo Open Access |
| id | wiley_oa_10_1002_jca_22141 |
| institution | Wiley Open Access |
| license_str_mv | http://creativecommons.org/licenses/by-nc/4.0/ |
| publishDate | 2024 |
| publisher | Wiley |
| record_format | wiley_oa |
| spellingShingle | Small but mighty: Case report and practical guidance for peripheral blood stem cell collection in small infants Hannah Walker Erin O'Reilly Zoe Millard Brendan Cusack Anna Duncan Luisa Clucas Jacqueline Fleming David Hughes Anthea Greenway David Metz Journal of Clinical Apheresis Small but mighty: Case report and practical guidance for peripheral blood stem cell collection in small infants Hannah Walker Erin O'Reilly Zoe Millard Brendan Cusack Anna Duncan Luisa Clucas Jacqueline Fleming David Hughes Anthea Greenway David Metz Journal of Clinical Apheresis AbstractModern apheresis devices, with increased procedural precision, automation, and monitoring, have been shown to allow for safe delivery of apheresis therapies in young children. Medical advances are increasing demand for apheresis procedures like mononuclear cell collection in infants <10 kg, including stem‐cell supported chemotherapy, cell collection for chimeric antigen receptor T cell development, and now ex vivo gene therapies for rare genetic diseases. Nevertheless, safe delivery in small infants involves a range of unique considerations and challenges, beyond just size, and experience will vary between centers. In this case report we describe our experience performing mononuclear cell collection in our smallest patient to date and outline a practice guideline developed following a literature review and discussion with both international experts and device representatives. This case may help to inform other clinicians aiming to provide apheresis care to very small infants in their own centers. 10.1002/jca.22141 http://creativecommons.org/licenses/by-nc/4.0/ |
| title | Small but mighty: Case report and practical guidance for peripheral blood stem cell collection in small infants |
| topic | Journal of Clinical Apheresis |
| url | https://onlinelibrary.wiley.com/doi/10.1002/jca.22141 |