A rare case of acute cerebellitis due to enterovirus treated with therapeutic plasma exchange: Case report and review of the literature

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Autores principales: Nihal Akçay, Neval Topal, Seda Yılmaz Semerci
Formato: Artículo Open Access
Publicado: Wiley 2024
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author Nihal Akçay
Neval Topal
Seda Yılmaz Semerci
author_facet Nihal Akçay
Neval Topal
Seda Yılmaz Semerci
Nihal Akçay
Neval Topal
Seda Yılmaz Semerci
collection Wiley Open Access
contents A rare case of acute cerebellitis due to enterovirus treated with therapeutic plasma exchange: Case report and review of the literature Nihal Akçay Neval Topal Seda Yılmaz Semerci Journal of Clinical Apheresis AbstractBackgroundAcute cerebellitis is a rare complication of pediatric infections. There are many reports that viral infections lead to neurological manifestations, including acute cerebellitis.MethodsA retrospective chart review was conducted for pediatric patients diagnosed with enterovirus cerebellitis between 2000 and 2024. The methods involved reviewing clinical and radiological records and assessing the treatment methods.ResultsCase ReportWe present the case of a 4‐year‐old immunocompetent child who initially presented with acute encephalopathy followed by truncal ataxia, and eventually received a diagnosis of postinfectious cerebellitis. Enterovirus real‐time polymerase chain reaction were positive in the nasopharyngeal swab. Therapeutic plasma exchange (TPE) was started due to neurological deterioration despite IVIG treatment. She improved significantly with TPE, and methylprednisolone treatment and was discharged in good health status. The patient is being followed up as neurologically normal.ConclusionAcute cerebellitis associated with enterovirus is a rare pediatric disorder. Early diagnosis and treatment with TPE in this severe case is thought to be preventive for the potentially fatal complications. 10.1002/jca.22142 http://onlinelibrary.wiley.com/termsAndConditions#vor
doi_str_mv 10.1002/jca.22142
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spellingShingle A rare case of acute cerebellitis due to enterovirus treated with therapeutic plasma exchange: Case report and review of the literature
Nihal Akçay
Neval Topal
Seda Yılmaz Semerci
Journal of Clinical Apheresis
A rare case of acute cerebellitis due to enterovirus treated with therapeutic plasma exchange: Case report and review of the literature Nihal Akçay Neval Topal Seda Yılmaz Semerci Journal of Clinical Apheresis AbstractBackgroundAcute cerebellitis is a rare complication of pediatric infections. There are many reports that viral infections lead to neurological manifestations, including acute cerebellitis.MethodsA retrospective chart review was conducted for pediatric patients diagnosed with enterovirus cerebellitis between 2000 and 2024. The methods involved reviewing clinical and radiological records and assessing the treatment methods.ResultsCase ReportWe present the case of a 4‐year‐old immunocompetent child who initially presented with acute encephalopathy followed by truncal ataxia, and eventually received a diagnosis of postinfectious cerebellitis. Enterovirus real‐time polymerase chain reaction were positive in the nasopharyngeal swab. Therapeutic plasma exchange (TPE) was started due to neurological deterioration despite IVIG treatment. She improved significantly with TPE, and methylprednisolone treatment and was discharged in good health status. The patient is being followed up as neurologically normal.ConclusionAcute cerebellitis associated with enterovirus is a rare pediatric disorder. Early diagnosis and treatment with TPE in this severe case is thought to be preventive for the potentially fatal complications. 10.1002/jca.22142 http://onlinelibrary.wiley.com/termsAndConditions#vor
title A rare case of acute cerebellitis due to enterovirus treated with therapeutic plasma exchange: Case report and review of the literature
topic Journal of Clinical Apheresis
url https://onlinelibrary.wiley.com/doi/10.1002/jca.22142